Antioxidant and Antipyretic Activities of Adansonia Digitata (African Baobab) Fruit, Leaf And Bark Extracts

The   study   was   conducted   to   evaluate the   antioxidant   and antipyretic activity of Adansonia digitata (African Baobab) fruit, leaf and bark extracts.  Antioxidant activity of plant part extracts were determined by free radical   Diphenylpicrylhydrazyl (DPPH) assay   while   the   antipyretic activity was assessed using experimental animals. Antioxidant activity of leaf extract showed a value of 13.40±0.77, bark extract 29.23±1.69 while fruit extract gave a value of 39.21±2.26. For the Antipyretic activity results, the average temperature of Albino Wister rats was   21.65±0.96 oC   before   fever   inducement   and 30.64±1.37 oC   after inducement. Following the administration of the leaf extract (400 mg/kg and 800 mg/kg), bark   extract (400 mg/kg   and   800 mg/kg) and   fruit   extract (400 mg/kg and 800 mg/kg), the body temperature of the albino rats fell to25.96±1.16 oC vs.   25.28±1.13 oC, 26.06±1.17 oC vs. 25.02±1.12 oC, and 25.78±1.15 oC vs. 24.30±1.09 oC respectively. The   results   showed   that   the   fruit   extract   has   a   higher antioxidant and antipyretic activity than bark and leaf extracts

Antibacterial Activity and Aphrodisiac Potential of the Ethanolic Extracts of Fadogia agretis (Sch winffax Hiern) Stem in Male Albino Rats

The research is aimed to evaluate the antibacterial activity and aphrodisiac potential of the ethanolic extracts of Fadogia agrestis (rubiaceae) stem in male albino rats. The antibacterial activity of the extracts were tested on four hospital isolates of staphylococcus aureus, Escherichia coli, Pseudomonas specie and Proteus spp at a concentration of 500µg using disc diffusion method. For aphrodisiac test, healthy, white male albino rats (Rattis novergicus) weighing 270 300g aged 5.0 5.5 months and female albino rats weighing 150 180g aged 3.5 5.4 months were used for the study. The male albino rats were orally dosed with 50mg/kg, 100mg/kg and 200mg/kg body weight respectively of the extract at 24hours intervals. Their sexual behaviour was evaluated for 15 minutes each. The plants extract was found to inhibit staphylococcus aureus and Pseudomonas specie. Aphrodisiac effect of the extract resulted in significant increase in mount behaviour. The antibacterial effects suggest their possible use for the treatment of infection that showed in vitro susceptibility. Also, the increase in the mounting behavior may be responsible for the aphrodisiac effect