976 research outputs found
Is more memory in evolutionary selection (de)stabilizing?
We investigate the effects of memory on the stability of evolutionary selection dynamics based on a multi-nomial logit model in an asset pricing model with heterogeneous beliefs. Whether memory is stabilizing or destabilizing depends in general on three key factors: (1) whether or not the weights on past observations are normalized; (2) the ecology of forecasting rules, in particular the average strength of trend extrapolation and the spread in biased forecasts, and (3) whether or not costs for information gathering of economic fundamentals have to be incurred.
Anticipating Information Needs Based on Check-in Activity
In this work we address the development of a smart personal assistant that is
capable of anticipating a user's information needs based on a novel type of
context: the person's activity inferred from her check-in records on a
location-based social network. Our main contribution is a method that
translates a check-in activity into an information need, which is in turn
addressed with an appropriate information card. This task is challenging
because of the large number of possible activities and related information
needs, which need to be addressed in a mobile dashboard that is limited in
size. Our approach considers each possible activity that might follow after the
last (and already finished) activity, and selects the top information cards
such that they maximize the likelihood of satisfying the user's information
needs for all possible future scenarios. The proposed models also incorporate
knowledge about the temporal dynamics of information needs. Using a combination
of historical check-in data and manual assessments collected via crowdsourcing,
we show experimentally the effectiveness of our approach.Comment: Proceedings of the 10th ACM International Conference on Web Search
and Data Mining (WSDM '17), 201
On the Rate of Convergence for a Characteristic of Multidimensional Birth-Death Process
We consider a multidimensional inhomogeneous birth-death process (BDP) and
obtain bounds on the rate of convergence for the corresponding one-dimensional
processes
Methodology of modern management of profit of sales of "intelligence - products" of high school
Исследуется проблема управления прибылью в процессе создания и реализации рынка образовательных услуг в Росси
Development of PancRISK, a urine biomarker-based risk score for stratified screening of pancreatic cancer patients
© The Author(s) 2019. Published by Springer Nature on behalf of Cancer Research UK.BACKGROUND: An accurate and simple risk prediction model that would facilitate earlier detection of pancreatic adenocarcinoma (PDAC) is not available at present. In this study, we compare different algorithms of risk prediction in order to select the best one for constructing a biomarker-based risk score, PancRISK. METHODS: Three hundred and seventy-nine patients with available measurements of three urine biomarkers, (LYVE1, REG1B and TFF1) using retrospectively collected samples, as well as creatinine and age, were randomly split into training and validation sets, following stratification into cases (PDAC) and controls (healthy patients). Several machine learning algorithms were used, and their performance characteristics were compared. The latter included AUC (area under ROC curve) and sensitivity at clinically relevant specificity. RESULTS: None of the algorithms significantly outperformed all others. A logistic regression model, the easiest to interpret, was incorporated into a PancRISK score and subsequently evaluated on the whole data set. The PancRISK performance could be even further improved when CA19-9, commonly used PDAC biomarker, is added to the model. CONCLUSION: PancRISK score enables easy interpretation of the biomarker panel data and is currently being tested to confirm that it can be used for stratification of patients at risk of developing pancreatic cancer completely non-invasively, using urine samples.Peer reviewe
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