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Contribution of male age to outcomes in assisted reproductive technologies—addressing methodological challenges
Objective—To evaluate the relation between male age and pregnancy outcome in donor oocyte assisted reproductive technology cycles Design—Retrospective cohort Setting—Private IVF center. Patients—1392 donor cycles from 1083 female recipients and their male partners Interventions—Oocyte donor cycles Main outcome measure(s)—Live birth Results—Increasing male age was associated with semen parameters including volume and motility; however, male age was not observed to have a statistically significant association with likelihood of live birth in donor cycles after adjustment for female recipient age. Conclusions—When treatment cycle number and female recipient age were taken into account, male age had no significant association with pregnancy outcomes in ART donor cycles in this study population