NEW METHODS TO SOLVE HIGH ORDER POTENTIAL USED IN CALCULATING NON-LINEAR WAVE LOADS

ABSTRACT In the present study, non-linear wave loads such as the wave-drift force, wave-drift damping and wave-drift added mass, acting on the body is considered based on the potential theory. To investigate non-linear wave loads, consistent perturbation expansion by means of two small parameters, i.e. the incident wave slope and the low frequency body motion, is performed on a moving frame (body-fixed) coordinate system. To avoid complicated free surface integrals as much as possible, new approach for the higher order potential in the interaction problem of low frequency motion and waves is suggested in the present work. Instead of integrals, derivative operators are defined to obtain special solutions efficientl

On the Introduction of an English Puppet Play into Foreign Language Activities and Its Effects

When observing pupils actually engaged in foreign language activities, I noticed that they exhibited two different patterns. Those accustomed to English actively speak English and take part in activities, but those lacking confidence take a passive stance toward the classes. This caused me to wonder what strategies might be employed to aid those pupils who feel some resistance to foreign language. I belong to my university’s puppet play group and utilize the puppets to foster communication with the pupils. At times, very shy pupil who struggle to converse open up and converse when faced with a puppet. Based on that experience, I formulated the hypothesis that utilizing puppets in an English puppet play would reduce pupil’s resistance to foreign language, foster in them an affinity for it, and yield benefits for the acquisition of the foreign language. I thereby proceeded to undertake this research to test that hypothesis

SoundBeam: Target sound extraction conditioned on sound-class labels and enrollment clues for increased performance and continuous learning

In many situations, we would like to hear desired sound events (SEs) while being able to ignore interference. Target sound extraction (TSE) aims at tackling this problem by estimating the sound of target SE classes in a mixture while suppressing all other sounds. We can achieve this with a neural network that extracts the target SEs by conditioning it on clues representing the target SE classes. Two types of clues have been proposed, i.e., target SE class labels and enrollment sound samples similar to the target sound. Systems based on SE class labels can directly optimize embedding vectors representing the SE classes, resulting in high extraction performance. However, extending these systems to the extraction of new SE classes not encountered during training is not easy. Enrollment-based approaches extract SEs by finding sounds in the mixtures that share similar characteristics to the enrollment. These approaches do not explicitly rely on SE class definitions and can thus handle new SE classes. In this paper, we introduce a TSE framework, SoundBeam, that combines the advantages of both approaches. We also perform an extensive evaluation of the different TSE schemes using synthesized and real mixtures, which shows the potential of SoundBeam.Comment: Submitted to IEEE/ACM Trans. Audio, Speech, and Language Processin

Ab initio investigation on oxygen defect clusters in UO2+x

By first-principles LSDA+U calculations, we revealed that the current physical picture of defective uranium dioxide suggested solely by neutron diffraction analysis is unsatisfactory. An understanding based on quantum theory has been established as a thermodynamical competition among point defects and cuboctahedral cluster, which naturally interprets the puzzled origin of the asymmetric O' and O'' interstitials. It also gives a clear and consistent agreement with most available experimental data. Unfortunately, the observed high occupation of O'' site cannot be accounted for in this picture and is still a challenge for theoretical simulations.Comment: 4 pages, 3 figures, title change

Real-time Perceptive Motion Control using Control Barrier Functions with Analytical Smoothing for Six-Wheeled-Telescopic-Legged Robot Tachyon 3

To achieve safe legged locomotion, it is important to generate motion in real-time considering various constraints in robots and environments. In this study, we propose a lightweight real-time perspective motion control system for the newly developed six-wheeled-telescopic-legged robot, Tachyon 3. In the proposed method, analytically smoothed constraints including Smooth Separating Axis Theorem (Smooth SAT) as a novel higher order differentiable collision detection for 3D shapes is applied to the Control Barrier Function (CBF). The proposed system integrating the CBF achieves online motion generation in a short control cycle of 1 ms that satisfies joint limitations, environmental collision avoidance and safe convex foothold constraints. The efficiency of Smooth SAT is shown from the collision detection time of 1 us or less and the CBF constraint computation time for Tachyon3 of several us. Furthermore, the effectiveness of the proposed system is verified through the stair-climbing motion, integrating online recognition in a simulation and a real machine.Comment: 8 pages, 8 figures, This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessibl

Novel concept microarray enabling PCR and multistep reactions through pipette-free aperture-to-aperture parallel transfer

<p>Abstract</p> <p>Background</p> <p>The microarray has contributed to developing the omic analysis. However, as it depends basically on the surface reaction, it is hard to perform bulk reactions and sequential multistep reactions. On the other hand, the popular microplate technology, which has a great merit of being able to perform parallel multistep reactions, has come to its limit in increasing the number of wells (currently, up to 9600) and reducing the volume to deal with due to the difficulty in operations.</p> <p>Results</p> <p>Here, we report a novel microarray technology which enables us to explore advanced applications, termed <it>microarray-with-manageable volumes </it>(MMV). The technical essence is in the pipette-free direct parallel transfer from well to well performed by centrifugation, evading the evaporation and adsorption-losses during handling. By developing the MMV plate, accompanying devices and techniques, generation of multiple conditions (256 kinds) and performance of parallel multistep reactions, including PCR and <it>in vitro tr</it>anslation reactions, have been made possible. These were demonstrated by applying the MMV technology to searching lysozyme-crystallizing conditions and selecting peptides aimed for Aβ-binding or cathepsin E-inhibition.</p> <p>Conclusions</p> <p>With the introduction of a novel concept microarray (MMV) technology, parallel and multistep reactions in sub-μL scale have become possible.</p

Case report: Rehabilitation course in thrombocytopenia, anasarca, fever, reticulin fibrosis/renal failure, and organomegaly syndrome complicated by cerebral infarction in the left parabolic coronary region

Although thrombocytopenia, anasarca, fever, reticulin fibrosis/renal failure, and organomegaly (TAFRO) syndrome was first reported in 2010, its pathogenesis and prognosis are still unknown. Moreover, reports on rehabilitation in patients with TAFRO are limited. In severe cases, dyspnea and muscle weakness could impede improvements in activities of daily living (ADL). However, reports on exercise intensity showed no worsening of TAFRO within the load of 11–13 on the Borg scale. Herein, we describe the rehabilitation and progress in a 61-year-old woman with TAFRO syndrome complicated by cerebral infarction from early onset to discharge. After cerebral infarction onset in the perforating artery, she was admitted to the intensive care unit due to decreased blood pressure and underwent continuous hemodiafiltration. Two weeks following transfer to a general ward, the patient started gait training using a brace due to low blood pressure, respiration, and tachycardia. After initiating gait training, increasing the amount of training was difficult due to a high Borg scale of 15–19, elevated respiratory rate, and worsening tachycardia. Furthermore, there was little improvement in muscle strength on the healthy side after continuous training, owing to long-term steroid administration. On day 100 after transfer, the patient was discharged home with a T-cane gait at a monitored level. The patient had severe hemiplegia due to complications with severe TAFRO syndrome delaying early bed release and gait training; tachycardia; and respiratory distress. Additionally, delayed recovery from muscle weakness on the non-paralyzed side made it difficult for the patient to walk and perform ADLs. Despite these issues, low-frequency rehabilitation was useful. However, low-frequency rehabilitation with gait training, using a Borg scale 15–19 orthosis, did not adversely affect the course of TAFRO syndrome