48 research outputs found
Long-term exposure to fine particulate matter and development of chronic obstructive pulmonary disease in the elderly
The impact of trans-boundary transport of carbonaceous aerosols on the regional air quality in the United States
University of HoustonHarvard UniversityEwha Womans UniversityPromoting Environmental Pesearch in Pan-Japan Sea Area : Young Researchers\u27 Network, Schedule: March 8-10,2006,Kanazawa Excel Hotel Tokyu, Japan, Organized by: Kanazawa University 21st-Century COE Program, Environmental Monitoring and Prediction of Long- & Short- Term Dynamics of Pan-Japan Sea Area ; IICRC(Ishikawa International Cooperation Research Centre), Sponsors : Japan Sea Research ; UNU-IAS(United Nations University Institute of Advanced Studies)+Ishikawa Prefecture Government ; City of Kanazaw
Evaluating a shared decision-making intervention regarding dialysis modality: development and validation of self-assessment items for patients with chronic kidney disease
Background Shared decision-making is a two-way symmetrical communication process in which clinicians and patients work together to achieve the best outcome. This study aimed to develop self-assessment items as a decision aid for choosing a dialysis modality in patients with chronic kidney disease (CKD) and to assess the construct validity of the newly developed items. Methods Five focus group interviews were performed to extract specific self-assessment items regarding patient values in choosing a dialysis modality. After survey items were refined, a survey of 330 patients, consisting of 152 hemodialysis (HD) and 178 peritoneal dialysis (PD) patients, was performed to validate the self-assessment items. Results The self-assessment for the decision aid was refined to 35 items. The structure of the final items appeared to have three dimensions of factors; health, lifestyle, and dialysis environment. The health factor consisted of 12 subscales (α = 0.724), the lifestyle factor contained 11 subscales (α = 0.624), and the dialysis environment factor was represented by 12 subscales (α = 0.694). A structural equation model analysis showed that the relationship between the decision aid factors (health, lifestyle, and dialysis environment), patients’ CKD perception, and cognition of shared decision-making differed between HD patients and PD patients. Conclusion We developed and validated self-assessment items as part of a decision aid to help patients with CKD. This attempt may assist CKD patients in making informed and shared decisions closely aligned with their values when considering dialysis modality
Mortality Burden Due to Short-term Exposure to Fine Particulate Matter in Korea
Objectives: Excess mortality associated with long-term exposure to fine particulate matter (PM2.5) has been documented. However, research on the disease burden following short-term exposure is scarce. We investigated the cause-specific mortality burden of short-term exposure to PM2.5 by considering the potential non-linear concentration–response relationship in Korea. Methods: Daily cause-specific mortality rates and PM2.5 exposure levels from 2010 to 2019 were collected for 8 Korean cities and 9 provinces. A generalized additive mixed model was employed to estimate the non-linear relationship between PM2.5 exposure and cause-specific mortality levels. We assumed no detrimental health effects of PM2.5 concentrations below 15 μg/m3. Overall deaths attributable to short-term PM2.5 exposure were estimated by summing the daily numbers of excess deaths associated with ambient PM2.5 exposure. Results: Of the 2 749 704 recorded deaths, 2 453 686 (89.2%) were non-accidental, 591 267 (21.5%) were cardiovascular, and 141 066 (5.1%) were respiratory in nature. A non-linear relationship was observed between all-cause mortality and exposure to PM2.5 at lag0, whereas linear associations were evident for cause-specific mortalities. Overall, 10 814 all-cause, 7855 non-accidental, 1642 cardiovascular, and 708 respiratory deaths were attributed to short-term exposure to PM2.5. The estimated number of all-cause excess deaths due to short-term PM2.5 exposure in 2019 was 1039 (95% confidence interval, 604 to 1472). Conclusions: Our findings indicate an association between short-term PM2.5 exposure and various mortality rates (all-cause, non-accidental, cardiovascular, and respiratory) in Korea over the period from 2010 to 2019. Consequently, action plans should be developed to reduce deaths attributable to short-term exposure to PM2.5
A Multiscale Tiered Approach to Quantify Contributions: A Case Study of PM2.5 in South Korea During 2010–2017
We estimated long-term foreign contributions to the particulate matter of 2.5 μm or less in diameter (PM2.5) concentrations in South Korea with a set of air quality simulations. The Weather Research and Forecasting (WRF)-Sparse Matrix Operator Kernel Emissions (SMOKE)-Community Multiscale Air Quality (CMAQ) modeling system was used to simulate the base and sensitivity case after a 50% reduction of foreign emissions. The effects of horizontal modeling grid resolutions (27- and 9-km) was also investigated. For this study, we chose PM2.5 in South Korea during 2010–2017 for the case study and emissions from China as a representative foreign source. The 9-km simulation results show that the 8-year average contribution of the Chinese emissions in 17 provinces ranged from 40–65%, which is ~4% lower than that from the 27-km simulation for the high-tier government segments (particularly prominent in coastal areas). However, for the same comparison for low-tier government segments (i.e., 250 prefectures), the 9-km simulation presented lowered the foreign contribution by up to 10% compared to that from the 27-km simulation. Based on our study results, we recommend using high-resolution modeling results for regional contribution analyses to develop an air quality action plan as the receptor coverage decreases
The Variability of Ozone Sensitivity to Anthropogenic Emissions with Biogenic Emissions Modeled by MEGAN and BEIS3
In this study, we examined how modeled ozone concentrations respond to changes in anthropogenic emissions when different modeled emissions of biogenic volatile organic compounds (BVOCs) are used. With biogenic emissions estimated by the Model of Emissions of Gases and Aerosols from Nature (MEGAN) and the Biogenic Emissions Inventory System Version 3 (BEIS3), the Community Multi-scale Air Quality with the High-order Direct Decouple Method (CMAQ-HDDM) simulations were conducted to acquire sensitivity coefficients. For the case study, we chose 17–26 August 2007, when the Southern Korean peninsula experienced region-wide ozone standard exceedances. The results show that modeled local sensitivities of ozone to anthropogenic emissions in certain NOx-saturated places can differ significantly depending on the method used to estimate BVOC emission, with an opposite trend of ozone changes alongside NOx reductions often shown in model runs using MEGAN and BEIS3. Findings of increased ozone concentrations with one model and decreased ozone concentrations with the other model implies that estimating BVOCs emissions is an important element in predicting variability in ozone concentration and determining the responses of ozone concentrations to emission changes, a discovery that may lead to different policy decisions related to air quality improvement. Quantitatively, areas in the 3-km modeling domain that experienced daily maximum one-hour ozone concentrations greater than 120 ppb (MDA1O3) showed differences of over 20 ppb in MDA1O3 values between model runs with MEGAN and BEIS3. For selected monitoring sites, the maximum difference in relative daily maximum eight-hour ozone concentrations (MDA8O3) response between the methods to model BVOCs was 4.2 ppb in MDA8O3 when we adopted a method similar to the Relative Reduction Factor used by the US Environmental Protection Agency (EPA)