40,455 research outputs found

    Photoinjector-generation of a flat electron beam with transverse emittance ratio of 100

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    The generation of a flat electron beam directly from a photoinjector is an attractive alternative to the electron damping ring as envisioned for linear colliders. It also has potential applications to light sources such as the generation of ultra-short x-ray pulses or Smith-Purcell free electron lasers. In this Letter, we report on the experimental generation of a flat-beam with a measured transverse emittance ratio of 100±20.2100\pm 20.2 for a bunch charge of ∌0.5\sim 0.5 nC; the smaller measured normalized root-mean-square emittance is ∌0.4\sim 0.4 ÎŒ\mum and is limited by the resolution of our experimental setup. The experimental data, obtained at the Fermilab/NICADD Photoinjector Laboratory, are compared with numerical simulations and the expected scaling laws.Comment: 5 pages, 3 figure

    Non-specific cellular uptake of surface-functionalized quantum dots

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    We report a systematic empirical study of nanoparticle internalization into cells via non-specific pathways. The nanoparticles were comprised of commercial quantum dots (QDs) that were highly visible under a fluorescence confocal microscope. Surface-modified QDs with basic biologically-significant moieties, e.g. carboxyl, amino, streptavidin were used, in combination with the surface derivatization with polyethylene glycol (PEG) in a range of immortalized cell lines. Internalization rates were derived from image analysis and a detailed discussion about the effect of nanoparticle size, charge and surface groups is presented. We find that PEG-derivatization dramatically suppresses the non-specific uptake while PEG-free carboxyl and amine functional groups promote QD internalization. These uptake variations displayed a remarkable consistency across different cell types. The reported results are important for experiments concerned with cellular uptake of surface-functionalized nanomaterials, both when non-specific internalization is undesirable and also when it is intended for material to be internalized as efficiently as possible. Published article at: http://iopscience.iop.org/0957-4484/21/28/285105/Comment: 14 pages 7 figure

    A Study on the Sudden Death of Entanglement

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    The dynamics of entanglement and the phenomenon of entanglement sudden death (ESD) \cite{yu} are discussed in bipartite systems, measured by Wootters Concurrence. Our calculation shows that ESD appears whenever the system is open or closed and is dependent on the initial condition. The relation of the evolution of entanglement and energy transfer between the system and its surroundings is also studied.Comment: Comments and criticism are welcome. Accepted by Phys. Lett.

    Neutrino Oscillations and Lepton Flavor Mixing

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    In view of the recent announcement on non-zero neutrino mass from Super-Kamiokande experiment, it would be very timely to investigate all the possible scenarios on masses and mixings of light neutrinos. Recently suggested mass matrix texture for the quark CKM mixing, which can be originated from the family permutation symmetry and its suitable breakings, is assumed for the neutrino mass matrix and determined by the four combinations of solar, atmospheric and LSND neutrino data and cosmological hot dark matter bound as input constraints. The charged-lepton mass matrix is assumed to be diagonal so that the neutrino mixing matrix can be identified directly as the lepton flavor mixing matrix and no CP invariance violation originates from the leptonic sector. The results favor hierarchical patterns for the neutrino masses, which follow from the case when either solar-atmospheric data or solar-HDM constraints are used.Comment: Latex, 9 page

    On Horizontal and Vertical Separation in Hierarchical Text Classification

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    Hierarchy is a common and effective way of organizing data and representing their relationships at different levels of abstraction. However, hierarchical data dependencies cause difficulties in the estimation of "separable" models that can distinguish between the entities in the hierarchy. Extracting separable models of hierarchical entities requires us to take their relative position into account and to consider the different types of dependencies in the hierarchy. In this paper, we present an investigation of the effect of separability in text-based entity classification and argue that in hierarchical classification, a separation property should be established between entities not only in the same layer, but also in different layers. Our main findings are the followings. First, we analyse the importance of separability on the data representation in the task of classification and based on that, we introduce a "Strong Separation Principle" for optimizing expected effectiveness of classifiers decision based on separation property. Second, we present Hierarchical Significant Words Language Models (HSWLM) which capture all, and only, the essential features of hierarchical entities according to their relative position in the hierarchy resulting in horizontally and vertically separable models. Third, we validate our claims on real-world data and demonstrate that how HSWLM improves the accuracy of classification and how it provides transferable models over time. Although discussions in this paper focus on the classification problem, the models are applicable to any information access tasks on data that has, or can be mapped to, a hierarchical structure.Comment: Full paper (10 pages) accepted for publication in proceedings of ACM SIGIR International Conference on the Theory of Information Retrieval (ICTIR'16

    Exceptionally Slow Rise in Differential Reflectivity Spectra of Excitons in GaN: Effect of Excitation-induced Dephasing

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    Femtosecond pump-probe (PP) differential reflectivity spectroscopy (DRS) and four-wave mixing (FWM) experiments were performed simultaneously to study the initial temporal dynamics of the exciton line-shapes in GaN epilayers. Beats between the A-B excitons were found \textit{only for positive time delay} in both PP and FWM experiments. The rise time at negative time delay for the differential reflection spectra was much slower than the FWM signal or PP differential transmission spectroscopy (DTS) at the exciton resonance. A numerical solution of a six band semiconductor Bloch equation model including nonlinearities at the Hartree-Fock level shows that this slow rise in the DRS results from excitation induced dephasing (EID), that is, the strong density dependence of the dephasing time which changes with the laser excitation energy.Comment: 8 figure

    Ameliorating effects of Mango (Mangifera indica L.) fruit on plasma ethanol level in a mouse model assessed with 1H-NMR based metabolic profiling

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    The ameliorating effects of Mango (Mangifera indica L.) flesh and peel samples on plasma ethanol level were investigated using a mouse model. Mango fruit samples remarkably decreased mouse plasma ethanol levels and increased the activities of alcohol dehydrogenase and acetaldehyde dehydrogenase. The 1H-NMR-based metabolomic technique was employed to investigate the differences in metabolic profiles of mango fruits, and mouse plasma samples fed with mango fruit samples. The partial least squares-discriminate analysis of 1H-NMR spectral data of mouse plasma demonstrated that there were clear separations among plasma samples from mice fed with buffer, mango flesh and peel. A loading plot demonstrated that metabolites from mango fruit, such as fructose and aspartate, might stimulate alcohol degradation enzymes. This study suggests that mango flesh and peel could be used as resources for functional foods intended to decrease plasma ethanol level after ethanol uptake
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