22,153 research outputs found
P381 MECHANO-ACTIVE CARTILAGE TISSUE ENGINEERING USING A HIGHLY ELASTIC SCAFFOLD AND BONE MARROW STEM CELLS
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Preliminary Observations on New Images of the Elysium Frozen Sea Deposits from HRSC Mars Express
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Synthetic biology for evolutionary engineering: from perturbation of genotype to acquisition of desired phenotype
With the increased attention on bio-based industry, demands for techniques that enable fast and effective strain improvement have been dramatically increased. Evolutionary engineering, which is less dependent on biological information, has been applied to strain improvement. Currently, synthetic biology has made great innovations in evolutionary engineering, particularly in the development of synthetic tools for phenotypic perturbation. Furthermore, discovering biological parts with regulatory roles and devising novel genetic circuits have promoted high-throughput screening and selection. In this review, we first briefly explain basics of synthetic biology tools for mutagenesis and screening of improved variants, and then describe how these strategies have been improved and applied to phenotypic engineering. Evolutionary engineering using advanced synthetic biology tools will enable further innovation in phenotypic engineering through the development of novel genetic parts and assembly into well-designed logic circuits that perform complex tasks.11Ysciescopu
using HYP-smeared staggered fermions in unquenched QCD
We present results for kaon mixing parameter calculated using
HYP-smeared improved staggered fermions on the MILC asqtad lattices. We use
three lattice spacings (, and fm), ten different
valence quark masses (), and several light sea-quark
masses in order to control the continuum and chiral extrapolations. We derive
the next-to-leading order staggered chiral perturbation theory (SChPT) results
necessary to fit our data, and use these results to do extrapolations based
both on SU(2) and SU(3) SChPT. The SU(2) fitting is particularly
straightforward because parameters related to taste-breaking and matching
errors appear only at next-to-next-to-leading order. We match to the continuum
renormalization scheme (NDR) using one-loop perturbation theory. Our final
result is from the SU(2) analysis, with the SU(3) result providing a (less
accurate) cross check. We find and ,
where the first error is statistical and the second systematic. The error is
dominated by the truncation error in the matching factor. Our results are
consistent with those obtained using valence domain-wall fermions on lattices
generated with asqtad or domain-wall sea quarks.Comment: 37 pages, 31 figures, most updated versio
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