758 research outputs found

    Determination of Cutting Date and Interval on Native Grass Management of Agricultural Waterways in South Korea

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    Agricultural waterways provide a buffer zone between crop fields and adjacent rivers or streams. Waterways are important resource for agriculture water management, water quality and biodiversity conservation. The total linear distance of waterway in Korea is about 180,000 km, and about 40% are concrete and about 60% are grassed waterways. At present, the percentage of concrete waterways is increasing because of their water management efficiency. Some argue that continued expansion of concrete waterways is not sustainable because it leads to potential-degradation of the earth\u27s environment. This concern has led to renewed efforts to use grassed waterways as an alternative to concrete. In addition, grassed waterways enhance the environment-friendly image of agriculture that Korea farmers want to promote. The objective of this experiment was to determine the effect of cutting date and interval of native grasses for water management efficiency of agricultural waterway

    Effect of Different Seeding Rate on Seed Production of the Rye Variety “Gogu” in Korea

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    The rye (Secale cereale L.) has been used as an excellent green manure crop and good forage crop in Korea. The rye is usually recommended as a winter crop for forage and green manure after either maize or rice in Korea (Heo et al., 2009). But most of its seeds are being imported from foreign countries because the seed productions have difficulty with latematuring and the heavy raining season in the ripening stage in Korea. Therefore, a new rye variety “Gogu” with an earlymaturing and high performance was bred by National Institute of Crop Science (NICS), Suwon, Korea in 2004. This study was carried out to determine the effect of seeding rate on the seed yield and agronomic characteristics of the rye variety “Gogu” in the north eastern area, Youngwol, Korea

    The Korean Mistletoe (Viscum album coloratum) Extract Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity

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    This study investigates the inhibitory effects of Korean mistletoe extract (KME) on adipogenic factors in 3T3-L1 cells and obesity and nonalcoholic fatty liver disease (NAFLD) in mice fed a high-fat diet. Male C57Bl/6 mice fed a high-fat diet were treated with KME (3 g/kg/day) for 15 weeks for the antiobesity and NAFLD experiments. Body weight and daily food intake were measured regularly during the experimental period. The epididymal pad was measured and liver histology was observed. The effects of KME on thermogenesis and endurance capacity were measured. The effects of KME on adipogenic factors were examined in 3T3-L1 cells. Body and epididymal fat pad weights were reduced in KME-treated mice, and histological examination showed an amelioration of fatty liver in KME-treated mice, without an effect on food consumption. KME potently induces mitochondrial activity by activating thermogenesis and improving endurance capacity. KME also inhibited adipogenic factors in vitro. These results demonstrate the inhibitory effects of KME on obesity and NAFLD in mice fed a high-fat diet. The effects appear to be mediated through an enhanced mitochondrial activity. Therefore, KME may be an effective therapeutic candidate for treating obesity and fatty liver caused by a high-fat diet

    Coordinated Beamforming with Limited BS Cooperation for Multicell Multiuser MIMO Broadcast Channel

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    The capacity of downlink multi-input multi-output (MIMO) systems is significantly limited by inter-cell co-channel interference (CCI). Improving the erformance of cell edge users who suffers strong inter-cell CCI is still a crucial issue. In this paper, coordinated beamforming (CBF)lgorithm for multicell multiuser MIMO system is proposed to cope with the presence of intel-cell CCI. In multicell environment with MIMO channel, limited base station (BS) cooperation is considered to design optimal transmit and receive beamformers which make interference-free at the receiver. Simulation results show that the proposed algorithms can improve the capacity of cell edge user effectively as well as the overall system capacity for multiuser multicell MIMO system

    Melanocortins induce interleukin 6 gene expression and secretion through melanocortin receptors 2 and 5 in 3T3-L1 adipocytes

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    Interleukin 6 (IL6) is a pleiotropic cytokine that not only affects the immune system, but also plays an active role in many physiological events in various organs. Notably, 35% of systemic IL6 originates from adipose tissues under noninflammatory conditions. Here, we describe a previously unknown function of melanocortins in regulating Il6 gene expression and production in 3T3-L1 adipocytes through membrane receptors which are called melanocortin receptors (MCRs). Of the five MCRs that have been cloned, MC2R and MC5R are expressed during adipocyte differentiation. α-Melanocyte-stimulating hormone (α-MSH) or ACTH treatment of 3T3-L1 adipocytes induces Il6 gene expression and production in a time- and concentration-dependent manner via various signaling pathways including the protein kinase A, p38 mitogen-activated protein kinase, cJun N-terminal kinase, and IκB kinase pathways. Specific inhibition of MC2R and MC5R expression with short interfering Mc2r and Mc5r RNAs significantly attenuated the α-MSH-induced increase of intracellular cAMP and both the level of Il6 mRNA and secretion of IL6 in 3T3-L1 adipocytes. Finally, when injected into mouse tail vein, α-MSH dramatically increased the Il6 transcript levels in epididymal fat pads. These results suggest that α-MSH in addition to ACTH may function as a regulator of inflammation by regulating cytokine production

    Predicting the Interactome of Xanthomonas oryzae pathovar oryzae for target selection and DB service

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    <p>Abstract</p> <p>Background</p> <p>Protein-protein interactions (PPIs) play key roles in various cellular functions. In addition, some critical inter-species interactions such as host-pathogen interactions and pathogenicity occur through PPIs. Phytopathogenic bacteria infect hosts through attachment to host tissue, enzyme secretion, exopolysaccharides production, toxins release, iron acquisition, and effector proteins secretion. Many such mechanisms involve some kind of protein-protein interaction in hosts. Our first aim was to predict the whole protein interaction pairs (interactome) of <it>Xanthomonas oryzae </it>pathovar oryzae (Xoo) that is an important pathogenic bacterium that causes bacterial blight (BB) in rice. We developed a detection protocol to find possibly interacting proteins in its host using whole genome PPI prediction algorithms. The second aim was to build a DB server and a bioinformatic procedure for finding target proteins in Xoo for developing pesticides that block host-pathogen protein interactions within critical biochemical pathways.</p> <p>Description</p> <p>A PPI network in Xoo proteome was predicted by bioinformatics algorithms: PSIMAP, PEIMAP, and iPfam. We present the resultant species specific interaction network and host-pathogen interaction, XooNET. It is a comprehensive predicted initial PPI data for Xoo. XooNET can be used by experimentalists to pick up protein targets for blocking pathological interactions. XooNET uses most of the major types of PPI algorithms. They are: 1) Protein Structural Interactome MAP (PSIMAP), a method using structural domain of SCOP, 2) Protein Experimental Interactome MAP (PEIMAP), a common method using public resources of experimental protein interaction information such as HPRD, BIND, DIP, MINT, IntAct, and BioGrid, and 3) Domain-domain interactions, a method using Pfam domains such as iPfam. Additionally, XooNET provides information on network properties of the Xoo interactome.</p> <p>Conclusion</p> <p>XooNET is an open and free public database server for protein interaction information for Xoo. It contains 4,538 proteins and 26,932 possible interactions consisting of 18,503 (PSIMAP), 3,118 (PEIMAP), and 8,938 (iPfam) pairs. In addition, XooNET provides 3,407 possible interaction pairs between two sets of proteins; 141 Xoo proteins that are predicted as membrane proteins and rice proteomes. The resultant interacting partners of a query protein can be easily retrieved by users as well as the interaction networks in graphical web interfaces. XooNET is freely available from <url>http://bioportal.kobic.kr/XooNET/</url>.</p

    Barotrauma developed during intra-hospital transfer -A case report-

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    A 74-year-old male patient receiving ventilatory support due to aspiration pneumonia developed bilateral pneumothorax, pneumopericardium, pneumomediastinum, pneumo-retroperitoneum, and subcutaneous emphysema, after manual ventilation while being transferred from the intensive care unit (ICU) to the operating room (OR). These complications were assumed to be secondary to inappropriate manual ventilation of the intubated patient. In addition, it is likely that the possible migration of an already marginally acceptable endotracheal tube (ETT) position during transport was the cause of these complications. Finally, aggravation of a latent pneumothorax might have contributed to these complications
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