Typhoon‐induced, highly nonlinear internal solitary waves off the east coast of Korea

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94585/1/grl22467.pd

Učinci gama-zračenja na folikule jajnika

In order to observe the morphological and endocrinological changes of the rat and mouse ovarian follicles by gamma-radiation, rats were whole-body irradiated with doses of 3.2 Gy and 8.0 Gy and mice with 2.9 Gy and 7.2 Gy. Sections of ovaria were examined by light microscopy. Concentrations of progesterone, testosterone, and estradiol in ovarian homogenate were determined by radioimmunoassay techniques. Gamma-radiation resulted in the increased percentage of atretic follicles in the groups killed on day 0, day 4, and day 8 after irradiation. The decrease in granulosa cell viability was found in animals killed on day 4 after irradiation. The finding of the high ratio of testosterone to estradiol compared to that of progesterone to testosterone suggests that aromatase activity — steroid biosynthesis from testosterone to estradiol — in granulosa cell could be affected by gamma-radiation.U radu su procjenjivane strukture i endokrinološke promjene u folikulima jajnika štakorica i mišica izazvane gama-zračenjem. Štakorice su bile izložene zračenju od 3,2 Gy ili 8,0 Gy, a mišice od 2,9 Gy ili 7,2 Gy. Životinje su usmrćene dana 0, dana 4, odnosno dana 8 nakon ozračenja. Rezovi debljine 7 µm pripremljeni su za mikroskopiranje. Koncentracije progesterona, testosterona i estradiola u homogenatu jajnika određene su specifičnim radioimunoesejem. Gama-zračenje uzrokovalo je povećanje broja atretičnih folikula u obje skupine životinja usmrćenih 4 odnosno 8 dana nakon ozračivanja. Gama-zračenje također je smanjilo životni vijek granuloza stanica u skupinama usmrćenim 4. dan nakon ozračivanja. Utvrđeno povećanje omjera testosterona prema estradiolu u usporedbi s omjerom progesterona prema testosteronu upućuje na to da gama-zračenje utječe na aktivnost aromataze u steroidnoj biosintezi testosterona u estradiol u granuloza stanicama

Internal solitons in the northeastern south China Sea. Part I: sources and deep water propagation

Author Posting. © IEEE, 2004. This article is posted here by permission of IEEE for personal use, not for redistribution. The definitive version was published in IEEE Journal of Oceanic Engineering 29 (2004): 1157-1181, doi:10.1109/JOE.2004.840839.A moored array of current, temperature, conductivity, and pressure sensors was deployed across the Chinese continental shelf and slope in support of the Asian Seas International Acoustics Experiment. The goal of the observations was to quantify the water column variability in order to understand the along- and across-shore low-frequency acoustic propagation in shallow water. The moorings were deployed from April 21–May 19, 2001 and sampled at 1–5 min intervals to capture the full range of temporal variability without aliasing the internal wave field. The dominant oceanographic signal by far was in fact the highly nonlinear internal waves (or solitons) which were generated near the Batan Islands in the Luzon Strait and propagated 485 km across deep water to the observation region. Dubbed trans-basin waves, to distinguish them from other, smaller nonlinear waves generated locally near the shelf break, these waves had amplitudes ranging from 29 to greater than 140 m and were among the largest such waves ever observed in the world’s oceans. The waves arrived at the most offshore mooring in two clusters lasting 7–8 days each separated by five days when no waves were observed.Within each cluster, two types of waves arrived which have been named type-a and type-b. The type-a waves had greater amplitude than the type-b waves and arrived with remarkable regularity at the same time each day, 24 h apart. The type-b waves were weaker than the type-a waves, arrived an hour later each day, and generally consisted of a single soliton growing out of the center of the wave packet. Comparison with modeled barotropic tides from the generation region revealed that: 1) The two clusters were generated around the time of the spring tides in the Luzon strait; and 2) The type-a waves were generated on the strong side of the diurnal inequality while the type-b waves were generated on the weaker beat. The position of the Kuroshio intrusion into the Luzon Strait may modulate the strength of the waves being produced. As the waves shoaled, the huge lead solitons first split into two solitons then merged together into a broad region of thermocline depression at depths less than 120 m. Elevation waves sprang up behind them as they continued to propagate onshore. The elevation waves also grew out of regions where the locally-generated internal tide forced the main thermocline down near the bottom. The “critical point” where the upper and lower layers were equal was a good indicator of when the depression or elevation waves would form, however this was not a static point, but rather varied in both space and time according to the presence or absence of the internal tides and the incoming trans-basin waves themselves.The planning, execution, and analysis of this work was supported by the U.S. Office of Naval Research Ocean Acoustics and Physical Oceanography Programs. Significant funding contributions were also made by the National Science Council of Taiwan

Feasibility Test of a Liquid Film Thickness Sensor on a Flexible Printed Circuit Board Using a Three-Electrode Conductance Method

Liquid film thickness measurements under temperature-varying conditions in a two-phase flow are of great importance to refining our understanding of two-phase flows. In order to overcome the limitations of the conventional electrical means of measuring the thickness of a liquid film, this study proposes a three-electrode conductance method, with the device fabricated on a flexible printed circuit board (FPCB). The three-electrode conductance method offers the advantage of applicability under conditions with varying temperatures in principle, while the FPCB has the advantage of usability on curved surfaces and in relatively high-temperature conditions in comparison with sensors based on a printed circuit board (PCB). Two types of prototype sensors were fabricated on an FPCB and the feasibility of both was confirmed in a calibration test conducted at different temperatures. With the calibrated sensor, liquid film thickness measurements were conducted via a falling liquid film flow experiment, and the working performance was tested

Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes

Particulate matter 2.5 (PM2.5), an atmospheric pollutant with an aerodynamic diameter of <2.5 μm, can cause serious human health problems, including skin damage. Since sebocytes are involved in the regulation of skin homeostasis, it is necessary to study the effects of PM2.5 on sebocytes. We examined the role of PM2.5 via the identification of differentially expressed genes, functional enrichment and canonical pathway analysis, upstream regulator analysis, and disease and biological function analysis through mRNA sequencing. Xenobiotic and lipid metabolism, inflammation, oxidative stress, and cell barrier damage-related pathways were enriched; additionally, PM2.5 altered steroid hormone biosynthesis and retinol metabolism-related pathways. Consequently, PM2.5 increased lipid synthesis, lipid peroxidation, inflammatory cytokine expression, and oxidative stress and altered the lipid composition and expression of factors that affect cell barriers. Furthermore, PM2.5 altered the activity of sterol regulatory element binding proteins, mitogen-activated protein kinases, transforming growth factor beta-SMAD, and forkhead box O3-mediated pathways. We also suggest that the alterations in retinol and estrogen metabolism by PM2.5 are related to the damage. These results were validated using the HairSkin® model. Thus, our results provide evidence of the harmful effects of PM2.5 on sebocytes as well as new targets for alleviating the skin damage it causes