51 research outputs found

    Juvenile Penalties for “Lawyering Up”: The Role of Counsel and Extralegal Case Characteristics

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    The presence of counsel for juveniles in the courtroom seems advantageous from a due process perspective, yet some studies suggest that juveniles receive harsher dispositions when represented by an attorney. This study tested whether a “counsel penalty” existed regardless of attorney type and, guided by prior sentencing literature, used a more comprehensive model to determine the influence of extralegal and contextual factors that may amplify the counsel penalty. Utilizing official data from a Northeastern state in a multilevel modeling strategy, this study found that regardless of the type of counsel retained, harsher sentences were received as compared with cases in which a juvenile was not represented by counsel even after controlling for offense type. Moreover, minority youth with public defenders and males with private counsel received harsher sentences while community characteristics did not appear to have a significant influence on sentencing decisions

    Who's Getting Cited: Representation of Women and Non-White Scholars in Major American Criminology and Criminal Justice Journals Between 1986-2005

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    This article presents findings from an ongoing study of the integration of women and non-white scholarship into the discipline of criminology and criminal justice. The most-cited women and non-white scholars in six major American journals were determined for 1986–2005 to investigate (1) if the dissemination of published research findings in criminology and criminal justice (CCJ) is affected by gender and race/ethnicity and (2) if changes in scholarly influence of women and non-white scholars in CCJ over 20 years exists. A number of explanations are suggested to account for gender and racial differentials in citation rates

    How People Disclose Themselves Differently According To The Strength Of Relationship In SNS?

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    Self-disclosure is defined as “act of revealing personal information to others” (Archer, 1980, p.183). It plays a key role in development and maintenance of relationships.Since many companies adopt social networking services for their organizational information sharing platform, it is important to identify the process of creating and maintaining social relationship in virtual spaces for successful adoption of SNS. In this research, we identify a self-disclosure as a driving factor for initiating and maintaining online social relationships.This research assumes that the self-disclose strategy adopted by participants in a communication process would be very similar between a face to face communication and a communication through SNS. In addition, this study explores that how the strength of social relationship does affects participants’ self-discloser strategy in SNS.Self-disclosure on SNS is multidimensional and it consists of five dimensions; intent to disclose, amount, the positive-negative nature, the honesty-accuracy, and general depth-control of disclosure. Our research indicates that strength of relationship affect negatively the amount of disclosure on SNS. SNS users, in other words, less reveal themselves in terms of both frequency and duration to other user in strong tie than in weak tie. We found that strength of social ties significantly influenced dimensions of self-disclosure except for the positive-negative nature of disclosure

    Decision-Making Deficits Are Associated With Learning Impairments in Female College Students at High Risk for Anorexia Nervosa: Iowa Gambling Task and Prospect Valence Learning Model

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    This study investigated deficits in decision-making ability in female college students at high risk for anorexia nervosa (AN) using the Iowa Gambling Task (IGT) and the prospect valence learning (PVL) model. Based on scores on the Korean version of the Eating Attitude Test-26 (KEAT-26), participants were assigned to either the high risk for AN group (n = 42) or the control group (n = 43). The high risk for AN group exhibited significantly lower total net scores and block net scores on the third, fourth, and fifth blocks of the IGT than the control group did. The high risk for AN group selected cards significantly more often from the disadvantageous A and B decks and less often from the advantageous D deck than the control group did. In addition, the block net scores of the high risk for AN group did not differ across the five blocks, whereas those of the control group increased as the trials progressed. There was a significant negative correlation between IGT total net score and total score on the KEAT−26. The high risk for AN group had significantly lower values than the control group on the learning and response consistency parameters of the PVL model. These results indicate that female college students at high risk for AN have deficits in decision-making ability, and that these deficits are related to difficulties in remembering experience obtained from earlier trials and applying it to later trials. These difficulties further lead them to make decisions randomly

    Suppression of lung cancer progression by biocompatible glycerol triacrylate–spermine-mediated delivery of shAkt1

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    Background: Polyethylenimine (PEI)-based nonviral gene-delivery systems are commonly employed because of their high transfection efficiency. However, the toxic nature of PEI is a significant obstacle in clinical gene therapy. In this study, we developed biocompatible glycerol triacrylate-spermine (GT-SPE) polyspermine as a nanosized gene carrier for potential lung cancer gene therapy. Methods: The GT-SPE was synthesized using the Michael addition reaction between GT and SPE. The molecular weight was characterized using gel permeability chromatography multiangle laser light scattering and the composition of the polymer was analyzed using proton nuclear magnetic resonance. Results: The GT-SPE successfully protected the DNA from nucleases. The average particle size of the GT-SPE was 121 nm with a zeta potential of +23.45 mV. The GT-SPE was found to be less toxic than PEI for various cell lines, as well as for a murine model. Finally, our results showed that the GT-SPE/small hairpin Akt1 (shAkt1) complex suppressed lung tumorigenesis in a K-ras(LA1) lung cancer mice model by inducing apoptosis through the Akt signaling pathway and cell cycle arrest. Aerosol delivered GT-SPE/shAkt1, which reduced matrix metalloproteinase-9 activity and suppressed the expression levels of proliferating cell nuclear antigen, as well as vascular endothelial growth factors and CD31, which are known proliferation and angiogenesis markers, respectively. Conclusion: Our data suggest that GT-SPE may be a candidate for short hairpin-shaped RNA-based aerosol lung cancer gene therapy

    Aerosol delivery of kinase-deficient Akt1 attenuates Clara cell injury induced by naphthalene in the lungs of dual luciferase mice

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    Conventional lung cancer therapies are associated with poor survival rates; therefore, new approaches such as gene therapy are required for treating cancer. Gene therapies for treating lung cancer patients can involve several approaches. Among these, aerosol gene delivery is a potentially more effective approach. In this study, Akt1 kinase-deficient (KD) and wild-type (WT) Akt1 were delivered to the lungs of CMV-LucR-cMyc-IRES-LucF dual reporter mice through a nose only inhalation system using glucosylated polyethylenimine and naphthalene was administrated to the mice via intraperitoneal injection. Aerosol delivery of Akt1 WT and naphthalene treatment increased protein levels of downstream substrates of Akt signaling pathway while aerosol delivery of Akt1 KD did not. Our results showed that naphthalene affected extracellular signal-regulated kinase (ERK) protein levels, ERK-related signaling, and induced Clara cell injury. However, Clara cell injury induced by naphthalene was considerably attenuated in mice exposed to Akt1 KD. Furthermore, a dual luciferase activity assay showed that aerosol delivery of Akt1 WT and naphthalene treatment enhanced cap-dependent protein translation, while reduced cap-dependent protein translation was observed after delivering Akt1 KD. These studies demonstrated that our aerosol delivery is compatible for in vivo gene delivery

    Aerosol Delivery of Small Hairpin Osteopontin Blocks Pulmonary Metastasis of Breast Cancer in Mice

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    Metastasis to the lung may be the final step in the breast cancer-related morbidity. Conventional therapies such as chemotherapy and surgery are somewhat successful, however, metastasis-related breast cancer morbidity remains high. Thus, a novel approach to prevent breast tumor metastasis is needed.Aerosol of lentivirus-based small hairpin osteopontin was delivered into mice with breast cancer twice a week for 1 or 2 months using a nose-only inhalation system. The effects of small hairpin osteopontin on breast cancer metastasis to the lung were evaluated using near infrared imaging as well as diverse molecular techniques. Aerosol-delivered small hairpin osteopontin significantly decreased the expression level of osteopontin and altered the expression of several important metastasis-related proteins in our murine breast cancer model.Aerosol-delivered small hairpin osteopontin blocked breast cancer metastasis. Our results showed that noninvasive targeting of pulmonary osteopontin or other specific genes responsible for cancer metastasis could be used as an effective therapeutic regimen for the treatment of metastatic epithelial tumors

    A management practicum in Isuzu Philippines Co.

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    The purposes of this study are to provide the student the experience from actual instructions that could be found outside of the school and a chance to display the student\u27s potentials and possibilities in real world. Also to let the student have the experience of working in a company located in the Philippines and adapting to the atmosphere and the environment to help the student have an idea of working in the country. The experiences learned during the On the Job Training will be the base for building future career, also finding the student\u27s aptitude. The student was able to achieve the purposes and the OJT tested the student\u27s capabilities successfully. The objectives of this study are to adapt in a new environment, to apply knowledge into real world, and to learn interpersonal relationship skills. There were set with the student\u27s needs, the considerations of what the student expects to learn from the OJT and understanding of the purposes of the curriculum OJT. The activities were related with the core management subjects such as Actonea, Actoneb, Manacct, Mgmtdat, etc, also Language subjects too. The student was not only assigned in the Executive office and conducted the tasks connected with assisting managers, but also practiced the other tasks under Customer Relations Group, and Finance Department. The student was able to use the knowledge to understand and do the tasks. Also the student could see the real business model and how the theories are applied in real world. The experience earned during OJT was helpful to the student to develop the communication skills, critical thinking, decision making, flexibility and adaptability

    Predictors of job satisfaction among police officers: Does personality matter?

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    The aim of this research was to enhance the theoretical foundation of job satisfaction within the field of policing. The data were collected through a self-report survey administered to a sample of sworn police officers (N = 87). The primary research question was whether personality characteristics significantly contribute to perceptions of job satisfaction beyond which could be explained through demographic and job characteristic variables. Although results of hierarchical multiple regressions revealed that overall personality measurement added to the variance accounted for in job satisfaction beyond demographic and job characteristic variables, none of the independent personality scales were significant predictors. Overall, results demonstrated that years of experience and the job characteristic factors of autonomy and feedback were the most important predictors of job satisfaction in this sample of police offers. Implications and future directions are discussed.
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