A Pregnant Adolescence with an Intact Hymen

Child sexual abuse is a public health problem due to both the act itself and its consequences, one of the most serious of which is adolescent pregnancy. Unfortunately, it is difficult to provide evidence of such sexual crimes by forensic gynecologic examinations based on only the visual inspection of genitalia. Moreover, anatomic variations of genitalia can make it quite difficult for a physician to make a diagnosis of rape. A 14-year-old pregnant girl presented at our hospital with the allegation of sexual abuse. Although her pregnancy was obvious due to shape of her abdomen, her hymen was determined to be intact after examination. She was examined in the gynecology department to check on the pregnancy and investigate her health status. Ultrasound imagining revealed that she was 4 months and 3 days pregnant. The goal of this presentation is to draw physicians’ attention to the anatomic variations of the hymen. Our findings indicate that it is not always easy to make a diagnosis of sexual intercourse; the practitioner must take a multidisciplinary approach and develop his/her genital examination knowledge and skills

Comparison of serum adiponectin and osteopontin levels along with metabolic risk factors between obese and lean women with and without PCOS

Introduction: The objective of this study was to investigate the possible relation between serum adiponectin and osteopontin levels as metabolic risk markers among women with different polycystic ovary syndrome (PCOS) phenotypes. Material and methods: In a University Hospital setting PCOS patients diagnosed according to Rotterdam Consensus Conference criteria with body mass index (BMI) between 18 and 35 were recruited. Results: Overall, 57 PCOS patients and 57 age- and BMI-matched healthy controls were included in the study. Luteinising hormone (LH) to follicle-stimulating hormone FSH ratio (LH/FSH), free androgen index (FAI), and dehydroepiandrosterone sulphate (DHEAS-S) was found to be significantly higher in women with PCOS. There was significant interaction between PCOS status and obesity for serum adiponectin levels. Although mean adiponectin and osteopontin levels were similar among cases and controls, a further two-way ANOVA comparison within lean and obese subgroups revealed adiponectin to be significantly lower in lean PCOS women than in lean controls. LH/FSH ratio and adiponectin levels were all found to differ between lean counterparts; however, they did not show any correlation with metabolic markers [cholesterol, homeostatic model assessment (HOMA) or C-reactive protein (CRP) levels] in overall lean women or in the lean PCOS subgroup. Conclusion: Serum adiponectin levels in lean PCOS women were significantly lower than those in lean controls. On the other hand, mean adiponectin and osteopontin levels were similar in PCOS cases and controls overall

DNA Repair Gene Polymorphism and the Risk of Mitral Chordae Tendineae Rupture

Polymorphisms in Lys939Gln XPC gene may diminish DNA repair capacity, eventually increasing the risk of carcinogenesis. The aim of the present study was to evaluate the significance of polymorphism Lys939Gln in XPC gene in patients with mitral chordae tendinea rupture (MCTR). Twenty-one patients with MCTR and thirty-seven age and sex matched controls were enrolled in the study. Genotyping of XPC gene Lys939Gln polymorphism was carried out using polymerase chain reaction-(PCR-) restriction fragment length polymorphism (RFLP). The frequencies of the heterozygote genotype (Lys/Gln-AC) and homozygote genotype (Gln/Gln-CC) were significantly different in MCTR as compared to control group, respectively (52.4% versus 43.2%, = 0.049; 38.15% versus 16.2%, = 0.018). Homozygote variant (Gln/Gln) genotype was significantly associated with increased risk of MCTR (OR = 2.059; 95% CI: 1.097-3.863; = 0.018). Heterozygote variant (Lys/Gln) genotype was also highly significantly associated with increased risk of MCTR (OR = 1.489; 95% CI: 1.041-2.129; = 0.049). The variant allele C was found to be significantly associated with MCTR (OR = 1.481; 95% CI: 1.101-1.992; = 0.011). This study has demonstrated the association of XPC gene Lys939Gln polymorphism with MCTR, which is significantly associated with increased risk of MCTR

Experimental and Numerical Investigation of the Effect of Different Temperature and Deformation Speeds on Mechanical Properties and Springback Behaviour in Al-Zn-Mg-Cu Alloy

WOS: 000492377900010Thanks to their low density and high strength, the 7XXX series aluminum alloys are widely used as a support/beam parts in the aerospace industry. This alloy is target in the lightening studies of the automotive industry and surveys for sheet metal are still in progress. It is a series of alloys that can be applied to the aging process and has the most effect on mechanical properties. As formability is quite weak, methods are investigated. In this study, tensile test, bending test and Erichsen tests are performed at different deformation rates and temperatures. As a result of the experiments, it has been seen that the formability increases at high temperature and low deformation rates. If paint baking time is long, there will be no loss of strength. Also, the bending process is modeled with the help of the finite element analysis programs and the springback estimations are examined. It is seen that the results of the modeling process are quite successful. The effect of the strain rate sensitivity is determined

Evaluation of Formability Under Different Deformation Modes for TWIP900 Steel

WOS: 000402040500001Automotive manufacturers always seek high strength and high formability materials for automotive bodies. Advanced high strength steels (AHSS) are excellent candidates for this purpose. These steels generally show a reasonable degree of formability, in addition to their high strength. One particular type is the twinning-induced plasticity (TWIP) steel, which is a high manganese austenite steel, and represents a second generation in AHSS. In this study, comprehensive deformation analysis of TWIP900CR steel including tensile, bending, Erichsen, and deep drawing of cylindrical cups tests is made. Finite element simulation of U and V shaped bending processes is also performed. Results indicate that the TWIP steel has good mechanical properties and high formability. However, spring-back is quite significant. The coining force should be considered in order to reduce the amount of springback. For springback prediction, it is found that the Yld2000-2d material model has better prediction capability than the Hill48 model

Comparison of performances of commercial TWIP900 and DP600 advanced high strength steels in automotive industry

WOS: 000384552000009Mechanical properties and formability of TWIP900 steel, which is a new material for automotive industry, are investigated. TWIP steels have a good combination of high strength and high formability. Therefore, they are very attractive for the automotive industry. The energy absorption capability of the steel during collisions is a significant advantage. The biggest disadvantage of this steel is the relatively high springback of stamped parts. Tensile and springback behaviors of the material are investigated and compared with DP600 steel which is widely used in automotive industry. Besides, yield surfaces and forming limit diagrams for both materials are modelled and compared with each other. Results indicate that the use of TWIP steel will contribute weight reduction significantly, but the springback issue needs to be resolved. In finite element modelling of TWIP steel, it is seen that the Swift model gives more accurate results than the Backofen and Holloman models