Topographic and Clinical Characteristics of a Sample of Jordanian Students

Purpose: To screen for keratoconus (KC) and potential associated risk factors in a sample of medical students. Methods: This cross sectional study included 120 medical students studying at The University of Jordan. They were randomly selected from a total of 400 students. Participants responded by completing a self-administered questionnaire. Following initial clinical evaluation, corneal tomography images and indices were analyzed by an experienced ophthalmologist, after which the participants were classified into: normal, KC suspects and KC patients. Results: A total of 120 participants (mean age, 23.1 ±0.5 years) were included in this study, 70 (58.3%) were females and 50 (41.7%) were males. Two subjects had KC, demonstrating a prevalence of 1.7% while five (4.2%) participants showed at least two abnormal indices and were considered as KC suspects.Conclusion: the result of this study is similar to other studies conducted in the Middle East, which indicates a higher prevalence of KC than other western countries. Combined with the significantly impaired vision-related quality of life and the relatively young onset of disease, the burden of keratoconus represents a significant public health concern

Outcome of Penetrating Keratoplasty (PKP) and Redo PKP among Jordanian Population

Background: The success of penetrating keratoplasty (PKP) is determined by the duration of graft survival, which is the time to graft failure. Our study aims to identify various indications of corneal graft among our Jordanian population, their success rate as well as spotting the light on cases of re-grafting. Methods: In this study, we analyzed data for patients who had PKP as well as re-do PKP in the period from January 2014 to June 2017. For each study eye, we identified pre-operative visual acuity as well as visual acuity at six months and one year. We also focused on the specific indication for PKP, the surgical procedure and graft clarity at one year post-op. On SPSS statistical analysis software, we used repeated measure ANOVA, Pearson correlations, and Fischer’s exact test to analyze our study’s variables.Results: We included a total of 230 patients in this study with a mean age of 34.22 (±19.32). They were 112 (48.7%) males and 118 (±51.3%) females. We found a significant difference in mean age and outcome (p< 0.001), as the mean age for patients with successful PKP was 31.55 (±16.55) compared to 44.1 (±25.1) for patients with failed PKP. the success rate for patients with KC as an indication was 96.7% compared to only 58.3% for other indications. We found that failure rate in redo surgeries was significantly higher than first time surgeries.Conclusion: Among the Jordanian population, we found that Keratoconus was the main indication for PKP in our population, where we also found that it was associated with the best prognosis