Russians in Dairen

How Russian emigrants preserved the Russo-Japanese war monuments in Dairen. The history of the Russian community in Dairen is described

The Russians on the Philippines

Describes the Russians’ life in the Philippines. They first appeared there in the early 1920s, arriving on board the Siberian flotilla ships where temporary residence was provided. There are descriptions of various activities of the Russians in the Philippines, and biographies of well-known figures

Kinematics of Spherical Milling Cutters Forming

© 2017 The Authors. Published by Elsevier Ltd. The mathematical relations between the helical surface on the sphere, the formlining, and the process of forming the spherical cutter by the disc-shaped tool are revealed. An algorithm and a program for calculating the spherical milling parameters based on kinematics of formation were developed, taking into account the kinematics of shaping, the determination of the profile of a disk tool for processing a spherical cutter. The effect of the parameters of the helical surface on the profile of the disk tool is investigated. To be able to integrate with other systems in the program, a system of inter-program data exchange - export of table of output variables in Microsoft Excel - was implemented

Tool creation and operation system development for large engineering enterprises

On the basis of JSC "KAMAZ", the article describes a new concept of the automated tool creation and operation (TCO) system with tool identification at all stages of the life cycle with the possibility of adaptation to any machine-building enterprise. Russian machine-building companies have traditionally made over 80% of the tool themself. Therefore, the concept of TCO system is wider than adopted in the European countries Tool management (TM) concept. A general structure of the classification is developed for all kinds of tool manufacture. The system allows the assignment of a unique code to each tool. This permits to create the preconditions for the development of subsystems of its purchasing, design, production and operation. © IDOSI Publications, 2014

Programmable folding of fusion RNA \u3cem\u3ein vivo\u3c/em\u3e and \u3cem\u3ein vitro\u3c/em\u3e driven by pRNA 3WJ motif of phi29 DNA packaging motor

Misfolding and associated loss of function are common problems in constructing fusion RNA complexes due to changes in energy landscape and the nearest-neighbor principle. Here we report the incorporation and application of the pRNA-3WJ motif of the phi29 DNA packaging motor into fusion RNA with controllable and predictable folding. The motif included three discontinuous ∼18 nucleotide (nt) fragments, displayed a distinct low folding energy (Shu D et al., Nature Nanotechnology, 2011, 6:658–667), and folded spontaneously into a leading core that enabled the correct folding of other functionalities fused to the RNA complex. Three individual fragments dispersed at any location within the sequence allowed the other RNA functional modules to fold into their original structures with authentic functions, as tested by Hepatitis B virus ribozyme, siRNA, and aptamers for malachite green (MG), spinach, and streptavidin (STV). Only nine complementary nucleotides were present for any two of the three ∼18-nt fragments, but the three 9 bp branches were so powerful that they disrupted other double strands with more than 15 bp within the fusion RNA. This system enabled the production of fusion complexes harboring multiple RNA functionalities with correct folding for potential applications in biotechnology, nanomedicine and nanotechnology. We also applied this system to investigate the principles governing the folding of RNA in vivo and in vitro. Temporal production of RNA sequences during in vivo transcription caused RNA to fold into different conformations that could not be predicted with routine principles derived from in vitro studies

RNA-Based Compositions and Adjuvants for Prophylactic and Therapeutic Treatment

The present invention is directed towards an artificial RNA nano structure comprising multiple external strands of RNA, each external strand comprising about 40-50 nucleotides; one internal strand of RNA comprising more than about 50 nucleotides; the internal strands and external strands assembled to form a triangle nanostructure, a square nanostructure, or a polygon nanostructure and a pRNA three-way junction (3WJ) motif at each vertex of the nanostructure. Such nanostructure can be provided in a composition together with an adjuvant for use in inducing the production of high affinity neutralizing antibodies or inhibitory antibodies, inducing the production of cytokines, inducing an immune response in a subject, or a combination thereof

Intellectual model control data of the module integration SAP-ERP and Teamcenter PLM

Constructed model intellectual control of data module integration of information systems based on multi-agent system and knowledge base. Developed structure and functional model of the integration module SAP-ERP and TeamCenter-PLM, which allows import and convert data from files, spreadsheets, TeamCenter-PLM in the required format with the further transfer in SAP-ERP. © IDOSI Publications, 2013

Scientific - industrial aspects of integration product lifecycle management and enterprise resource planning systems

The developed module will provide a dynamic implementation of the integration information systems such as product lifecycle management (PLM), enterprise resource planning (ERP) and others of the enterprise through the use of intelligent agents and knowledge based on experience and rules. Integration module is independent of the software architecture of information systems, because it uses with the embedded integration solutions of different systems. It can work with two or more information systems using bidirectional data transmission scheme. The result will be to minimize errors by eliminating the human factor, the exclusion of manual labor and increase efficiency of decision making. © IDOSI Publications, 2013