Small Footprint Multilayered Millimeter-Wave Antennas and Feeding Networks for Multi-Dimensional Scanning and High-Density Integrated Systems

This paper overviews the state-of-the-art of substrate integrated waveguide (SIW) techniques in the design and realization of innovative low-cost, low-profile and low-loss (L3) millimeter-wave antenna elements, feeding networks and arrays for various wireless applications. Novel classes of multilayered antenna structures and systems are proposed and studied to exploit the vertical dimension of planar structures to overcome certain limita-tions in standard two-dimensional (2-D) topologies. The developed structures are based on two techniques, namely multi-layer stacked structures and E-plane corners. Differ-ent E-plane structures realised with SIW waveguide are presented, thereby demonstrating the potential of the proposed techniques as in multi-polarization antenna feeding. An array of 128 elements shows low SLL and height gain with just 200g of the total weight. Two versions of 2-D scanning multi-beam are presented, which effectively combine frequency scanning with beam forming networks. Adding the benefits of wide band performance to the multilayer structure, two bi-layer structures are investigated. Different stacked antennas and arrays are demonstrated to optimise the targeted antenna performances in the smallest footprint possible. These structures meet the requirement for developing inexpensive compact millimeter-wave antennas and antenna systems. Different structures and architectures are theoretically and experimentally studied and discussed for specific space- and ground-based appli-cations. Practical issues such as high-density integration and high-volume manufacturability are also addressed

Genetic variation and possible origins of weedy rice found in California.

Control of weeds in cultivated crops is a pivotal component in successful crop production allowing higher yield and higher quality. In rice-growing regions worldwide, weedy rice (Oryza sativa f. spontanea Rosh.) is a weed related to cultivated rice which infests rice fields. With populations across the globe evolving a suite of phenotypic traits characteristic of weeds and of cultivated rice, varying hypotheses exist on the origin of weedy rice. Here, we investigated the genetic diversity and possible origin of weedy rice in California using 98 simple sequence repeat (SSR) markers and an Rc gene-specific marker. By employing phylogenetic clustering analysis, we show that four to five genetically distinct biotypes of weedy rice exist in California. Analysis of population structure and genetic distance among individuals reveals diverse evolutionary origins of California weedy rice biotypes, with ancestry derived from indica, aus, and japonica cultivated rice as well as possible contributions from weedy rice from the southern United States and wild rice. Because this diverse parentage primarily consists of weedy, wild, and cultivated rice not found in California, most existing weedy rice biotypes likely originated outside California

Vibrational exciton nanoimaging of phases and domains in porphyrin nanocrystals.

Much of the electronic transport, photophysical, or biological functions of molecular materials emerge from intermolecular interactions and associated nanoscale structure and morphology. However, competing phases, defects, and disorder give rise to confinement and many-body localization of the associated wavefunction, disturbing the performance of the material. Here, we employ vibrational excitons as a sensitive local probe of intermolecular coupling in hyperspectral infrared scattering scanning near-field optical microscopy (IR s-SNOM) with complementary small-angle X-ray scattering to map multiscale structure from molecular coupling to long-range order. In the model organic electronic material octaethyl porphyrin ruthenium(II) carbonyl (RuOEP), we observe the evolution of competing ordered and disordered phases, in nucleation, growth, and ripening of porphyrin nanocrystals. From measurement of vibrational exciton delocalization, we identify coexistence of ordered and disordered phases in RuOEP that extend down to the molecular scale. Even when reaching a high degree of macroscopic crystallinity, identify significant local disorder with correlation lengths of only a few nanometers. This minimally invasive approach of vibrational exciton nanospectroscopy and -imaging is generally applicable to provide the molecular-level insight into photoresponse and energy transport in organic photovoltaics, electronics, or proteins

Predicting Business Distress Using Neural Network in SME-Arab Region

The paper analyzes the financial and operational measures for Small and medium-sized enterprises (SME) business distress for predicting credit worthiness by using panel data of 110 observations from 22 SME companies for a period of 5 years (2009 – 2013). Panel logistic and Neural Network (NN) models are developed as alternative techniques for predicting the business distress.  The result suggests that cash cycle, net fixed assets, and leverage ratio are key factors in making credit decisions by lenders. The logistic model overall correctly classified 70 percent while NN framework outperformed the logistic model with 93 percent overall correct classification in training phase, and 83 percent in testing phase. The study opens up potential opportunities for the lending firms to adopt advanced analytical frameworks for predicting distress behavior of business firms. Keywords: SME, Business distress, Arab region, Petrochemical sub-sectors, Logit Model, Neural Network.   JEL codes: G29, G3

Use of evidence to support healthy public policy: a policy effectiveness-feasibility loop

Public policy plays a key role in improving population health and in the control of diseases, including non-communicable diseases. However, an evidence-based approach to formulating healthy public policy has been difficult to implement, partly on account of barriers that hinder integrated work between researchers and policy-makers. This paper describes a “policy effectiveness–feasibility loop” (PEFL) that brings together epidemiological modelling, local situation analysis and option appraisal to foster collaboration between researchers and policy-makers. Epidemiological modelling explores the determinants of trends in disease and the potential health benefits of modifying them. Situation analysis investigates the current conceptualization of policy, the level of policy awareness and commitment among key stakeholders, and what actually happens in practice, thereby helping to identify policy gaps. Option appraisal integrates epidemiological modelling and situation analysis to investigate the feasibility, costs and likely health benefits of various policy options. The authors illustrate how PEFL was used in a project to inform public policy for the prevention of cardiovascular diseases and diabetes in four parts of the eastern Mediterranean. They conclude that PEFL may offer a useful framework for researchers and policy-makers to successfully work together to generate evidence-based policy, and they encourage further evaluation of this approach

Aminolevulinic Acid mediated Photodynamic Therapy of Human Meningioma: an in vitro Study on Primary Cell Lines

Objective: Five-aminolevulinic acid (5-ALA)-induced porphyrins in malignant gliomas are potent photosensitizers. Promising results of ALA-PDT (photodynamic therapy) in recurrent glioblastomas have been published. Recently, 5-ALA-induced fluorescence was studied in meningioma surgery. Here, we present an experimental study of ALA-PDT in an in vitro model of primary meningioma cell lines. Methods: We processed native tumor material obtained intra-operatively within 24 h for cell culture. Epithelial membrane antigen (EMA) immunohistochemistry was performed after the first passage to confirm that cells were meningioma cells. For 5-ALA-PDT treatment, about 5000 cells per well were seeded in 20 wells of a blank 96-well plate. Each block of 4 wells was inoculated with 150 µL of 0, 25, 50 and 100 µg/mL 5-ALA solutions; one block was used as negative control without 5-ALA and without PDT. Following incubation for 3 h PDT was performed using a laser (635 nm, 18.75 J/cm2). The therapeutic response was analyzed by the water soluble tetrazolium salt (WST-1) cell viability assay 90 min after PDT. Results: 5-ALA-PDT was performed in 14 primary meningioma cell lines. EMA expression was verified in 10 primary cell cultures. The remaining 4 were EMA negative and PDT was without any effect in these cultures. All 10 EMA-positive cell lines showed a significant and dose-dependent decrease in viability rate (p < 0.001). Cell survival at 5-ALA concentrations of 12.5, 25, 50 and 100 μg/mL was 96.5% ± 7.6%, 67.9% ± 29.9%, 24.0% ± 16.7% and 13.8% ± 7.5%, respectively. For the negative controls (no 5-ALA/PDT and ALA/no PDT), the viability rates were 101.72% ± 3.5% and 100.17% ± 3.6%, respectively. The LD50 for 5-ALA was estimated between 25 and 50 µg/mL. Conclusion: This study reveals dose-dependent cytotoxic effects of 5-ALA-PDT on primary cell lines of meningiomas. Either 5-ALA or PDT alone did not affect cell survival. Further efforts are necessary to study the potential therapeutic effects of 5-ALA-PDT in vivo

Shock tube study of the ignition and combustion of aluminum

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77231/1/AIAA-1984-1201-726.pd

PCSK4 (proprotein convertase subtilisin/kexin type 4)

Review on PCSK4 (proprotein convertase subtilisin/kexin type 4), with data on DNA, on the protein encoded, and where the gene is implicated

PCSK5 (Proprotein Convertase Subtilisin/Kexin Type 5)

Review on PCSK5 (Proprotein Convertase Subtilisin/Kexin Type 5), with data on DNA, on the protein encoded, and where the gene is implicated