5 research outputs found
EXPRESSION OF P21 IS DEPENDENT ON OR INDEPENDENT OF P53 IN CARCINOMA EX PLEOMORPHIC ADENOMA (UNDIFFERENTIATED AND ADENOCARCINOMA TYPES)
Evaluation of preparedness of healthcare student volunteers against Middle East respiratory syndrome coronavirus (MERS-CoV) in Makkah, Saudi Arabia: a cross-sectional study
Efficacy of nanoceria for periodontal tissues alteration in glutamate-induced obese rats—multidisciplinary considerations for personalized dentistry and prevention
Review of Difficulty Indices for Removal of Impacted Third Molars and a New Classification of Difficulty Indices
Product of natural evolution (SARS, MERS, and SARS-CoV-2); deadly diseases, from SARS to SARS-CoV-2
SARS-CoV-2, the virus causing COVID-19, is a single-stranded RNA virus belonging to the order Nidovirales, family Coronaviridae, and subfamily Coronavirinae. SARS-CoV-2 entry to cellsis initiated by the binding of the viral spike protein (S) to its cellular receptor. The roles of S protein in receptor binding and membrane fusion makes it a prominent target for vaccine development. SARS-CoV-2 genome sequence analysis has shown that this virus belongs to the beta-coronavirus genus, which includes Bat SARS-like coronavirus, SARS-CoV and MERS-CoV. A vaccine should induce a balanced immune response to elicit protective immunity. In this review, we compare and contrast these three important CoV diseases and how they inform on vaccine development