2014-2015 Philharmonia No. 4

Concert Date & Time: February 7, 2015 at 7:30 PM | February 8, 2015 at 4:00 PM Program Märchen von der schönen Melusine (The Fair Melusina), op.32 / Felix Mendelssohn Concerto for Flute and Orchestra (2013) / Behzad Ranjbaran Harold en Italie: Symphonie en 4 Parties, op. 16 / Hector Berliozhttps://spiral.lynn.edu/conservatory_philharmonia/1014/thumbnail.jp

2011-2012 Master Class - Jeffrey Khaner (Flute)

https://spiral.lynn.edu/conservatory_masterclasses/1069/thumbnail.jp

The transcription factor Pitx2 positions the embryonic axis and regulates twinning

Embryonic polarity of invertebrates, amphibians and fish is specified largely by maternal determinants, which fixes cell fates early in development. In contrast, amniote embryos remain plastic and can form multiple individuals until gastrulation. How is their polarity determined? In the chick embryo, the earliest known factor is cVg1 (homologous to mammalian growth differentiation factor 1, GDF1), a transforming growth factor beta (TGFβ) signal expressed posteriorly before gastrulation. A molecular screen to find upstream regulators of cVg1 in normal embryos and in embryos manipulated to form twins now uncovers the transcription factor Pitx2 as a candidate. We show that Pitx2 is essential for axis formation, and that it acts as a direct regulator of cVg1 expression by binding to enhancers within neighbouring genes. Pitx2, Vg1/GDF1 and Nodal are also key actors in left–right asymmetry, suggesting that the same ancient polarity determination mechanism has been co-opted to different functions during evolution

Sonata in E-flat Major for Flute and Piano, Op. 120, No. 2 / Johannes Brahms

Sonata in E-flat major is composed by Johannes Brahms, originally for B-flat clarinet and piano, and edited by Jeffrey Khaner

Czech Flute Music: Schulhoff, Feld, Martinů, Dvořák

Performers Jeffrey Khaner, flute Charles Abramovic, piano Contents Sonata / Erwin Schulhoff -- Sonata / Jinfřich Feld -- Sonata No. 1 / Bohuslav Martinů -- Sonatatina in G / Antonín Dvořák

Czech Flute Music: Schulhoff, Feld, Martinů, Dvořák

Performers Jeffrey Khaner, flute Charles Abramovic, piano Contents Sonata / Erwin Schulhoff -- Sonata / Jinfřich Feld -- Sonata No. 1 / Bohuslav Martinů -- Sonatatina in G / Antonín Dvořák

Sonata in F minor for Flute and Piano, Op. 120, No. 1 / Johannes Brahms

Sonata in F Minor, composed by Johannes Brahms, originally for B-flat clarinet and piano, and edited by Jeffrey Khaner