The prevalence of HBV infection in the cohort of IDPs of war against terrorism in Malakand Division of Northern Pakistan

<p>Abstract</p> <p>Background</p> <p>Hepatitis B is an important public health problem in the Pakistani population and is the major cause of chronic hepatitis, cirrhosis, fibrosis and hepatocellular carcinoma. High prevalence of HBV infections has been observed especially in areas of low economic status. In spite of effective immunization programs, no significant change has been observed in the epidemiology of HBV in the rural areas of Pakistan (~67.5% of the total population) mainly due to lack of interest from government authorities and poor hygienic measures. The current study was aimed at estimating the prevalence and risk factors associated with HBV infection within internally displaced persons (IDPs) due to war against terrorism in the Malakand Division of Northern Pakistan.</p> <p>Methods</p> <p>Blood samples from 950 IDPs suspected with HBV infection (including both males and females) were collected and processed with commercial ELISA kits for HBsAg, Anti HBs, HBeAg, Anti HBe antibodies. The samples positive by ELISA were confirmed for HBV DNA by real-time PCR analysis.</p> <p>Results</p> <p>The overall prevalence of HBV observed was 21.05% of which 78.5% were males and 21.5% were females. Most confirmed HBV patients belong to the Malakand and Dir (lower) district. High-risk of infection was found in the older subjects 29.13% (46-60 years), while a lower incidence (11.97%) was observed in children aged <15 years. Lack of awareness, socioecomic conditions, sexual activities and sharing of razor blades, syringes and tattooing needles were the most common risk factors of HBV infection observed during the cohort of patients.</p> <p>Conclusion</p> <p>The present study, revealed for the first time a high degree of prevalence of HBV infection in rural areas of Northern Pakistan. The noticed prevalence is gender- and age-dependent that might be due to their high exposures to the common risk factors. To avoid the transmission of HBV infection proper awareness about the possible risk factors and extension of immunization to the rural areas are recommended.</p

Drivers of farmers’ intention to adopt integrated pest management: a case study of vegetable farmers in Pakistan

Abstract: Integrated pest management adoption is quite low around the globe, particularly in developing countries, due to different factors. Here, we examine the factors affecting the intention of Pakistani farmers to adopt integrated pest management practices in vegetable production using a structured questionnaire. We interviewed 301 vegetable growers in Multan, Pakistan. The reliability and validity of the data, along with the underlying relationship between the observed variables, were identified through exploratory factor analysis. The majority of the farmers (79.4%) relied on pesticides for pest control. More than four out of 10 of the respondents (43.8%) reported that okra received the highest application of pesticides followed by potato (24.5%) and cauliflower (17.9%). Integrated pest management was currently non‐existent among the vegetable growers of the study area. The latent factors—“knowledge of the adverse effects of pesticide,” “belief in the efficacy of non‐chemical pest control measures,” “perceived barriers to the adoption of integrated pest management,” “progressive farming approach,” and “intention to adopt integrated pest management”—were subsequently confirmed using confirmatory factor analysis. The structural equation model suggested that the intention to adopt integrated pest management is significantly affected by farmers’ knowledge of the adverse effects of pesticides (β = 0.274, z‐value = 3.082, P = 0.002). An increase in farmers’ awareness of the harmful effects of pesticides could lead to integrated pest management adoption for pest control. The scale for intention to adopt integrated pest management developed in this study can be used in future studies and provide valuable insights to the policymakers for devising integrated pest management adoption campaigns in the study area