225 research outputs found
Integral population control of a quadratic dimerization process
Moment control of a simple quadratic reaction network describing a
dimerization process is addressed. It is shown that the moment closure problem
can be circumvented without invoking any moment closure technique. Local
stabilization and convergence of the average dimer population to any desired
reference value is ensured using a pure integral control law. Explicit bounds
on the controller gain are provided and shown to be valid for any reference
value. As a byproduct, an explicit upper-bound of the variance of the monomer
species, acting on the system as unknown input due to the moment openness, is
obtained. The obtained results are illustrated by an example relying on the
simulation of a cell population using stochastic simulation algorithms.Comment: 7 pages; 3 figures; accepted at the 52nd IEEE Conference on Decision
and Contro
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