Structural model of factors contributing to the motivational problem of taking shortcuts at construction workplaces in the Kingdom of Saudi Arabia

An unsafe act is a type of work that involves some risk. Since more than a decade, unsafe act has accounted as a foremost cause of work-related accident, especially in the field of construction. Several attempts have been made to reduce the causes of unsafe acts; however, shortcut, which is a notable type of unsafe act, has received little attention in previous works, even though some of causal effects have been attributed to this habit. This paper aims to reveal an unexplained proportion that can be explained by different underlying causes of motivational problems to shortcuts rather than by habit. Accordingly, two structural models have been proposed based on quantitative and qualitative data from previous reviews associated with the effects on negative feeling and thinking on risk management. These models were tested using on Exploratory Factor analysis (EFA) and Confirmatory Factor Analysis (CFA) on data collected from a cross-section survey conducted at construction sites in largest cities within the Kingdom of Saudi Arabia (KSA), where large number of accidents in these cities occurred. Data of 204 respondents of the mailed questionnaires were analyzed after screening all responses. Statistical Package for Social Sciences (SPSS) (version 22) was used to test for Structural Equation Model (SEM) assumptions. The developed hypotheses were tested and model with the best fit was identified. Findings revealed that 45%–55% of the motivational problems to shortcuts were explained by the selected structural model

An Overview on Phenotypic and Genotypic Characterisation of Carbapenem-Resistant Enterobacterales

Improper use of antimicrobials has resulted in the emergence of antimicrobial resistance (AMR), including multi-drug resistance (MDR) among bacteria. Recently, a sudden increase in Carbapenem-resistant Enterobacterales (CRE) has been observed. This presents a substantial challenge in the treatment of CRE-infected individuals. Bacterial plasmids include the genes for carbapenem resistance, which can also spread to other bacteria to make them resistant. The incidence of CRE is rising significantly despite the efforts of health authorities, clinicians, and scientists. Many genotypic and phenotypic techniques are available to identify CRE. However, effective identification requires the integration of two or more methods. Whole genome sequencing (WGS), an advanced molecular approach, helps identify new strains of CRE and screening of the patient population; however, WGS is challenging to apply in clinical settings due to the complexity and high expense involved with this technique. The current review highlights the molecular mechanism of development of Carbapenem resistance, the epidemiology of CRE infections, spread of CRE, treatment options, and the phenotypic/genotypic characterisation of CRE. The potential of microorganisms to acquire resistance against Carbapenems remains high, which can lead to even more susceptible drugs such as colistin and polymyxins. Hence, the current study recommends running the antibiotic stewardship programs at an institutional level to control the use of antibiotics and to reduce the spread of CRE worldwide