Ovarian fibroma with elevated CA125 and OVA1 in postmenopausal woman

Ovarian fibroma is a sexcord stromal tumor, which accounts for 4% of all ovarian tumors. It is uncommon benign tumor of ovary. Clinically, it is asymptomatic and may typically be detected during routine gynecological examinations. It may be associated with ascitis and hydrothorax known as Meig's Syndrome. Usually these ovarian tumors are unilateral, solid, hard masses with small areas of cystic degeneration. Due to their solid structure, these benign tumors are sometimes confused with malignant ovarian neoplasm during clinical evaluation. A 59 year old postmenopausal woman presented with flank pain and new onset urinary incontinence. Ultrasound evaluation revealed a pelvic mass. Labs showed elevated tumor marker level. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Pathological examination however revealed an ovarian fibroma. During the postmenopausal years, the ovaries become atrophic. The incidence ovarian neoplasm increases with age. A suspicious or persistent complex mass and increased tumor marker like CA125 and OVA1 in post-menopausal woman requires surgical evaluation. The traditional diagnostic tools for ovarian tumors are bimanual examination, pelvic ultrasound and measuring serum biomarker like CA125 level, but these methods have low specificity and sensitivity. Now-a-days the role of some tumor marker such as OVA1in the management of ovarian tumor has been approved by FDA.

2-[1-(3-{2-[(2-Hy­droxy­benzyl­idene)amino]­phen­oxy}prop­yl)-1H-1,3-benzodiazol-2-yl]phenol

In the title compound, C29H25N3O3, the imine double bond has an E configuration. The dihedral angle between the hy­droxy­phenyl and benzene rings in the imine moiety is 26.95 (9)°, and the dihedral angle between the hy­droxy­phenyl and benzimidazole rings in the other moiety is 14.83 (9)°. These angles are probably limited to small values as a consequence of two strong intra­molecular O—H⋯N hydrogen bonds formed between the hy­droxy groups and the imine and imidazole N atoms. The aliphatic chain linking the two ring systems has a gauche conformation, as reflected in C—C—C—O torsion angle of 70.9 (2)°

Pyogenic Granuloma in Pregnancy: A Case Report

BACKGROUND AND OBJECTIVE: Pyogenic granuloma is a lesion that affects pregnant women between the third and ninth month of pregnancy. It is a benign vascular proliferative disease that often appears on the gingiva, but may also appear on the lips, skin and extramucosal tissues. The purpose of the report is to introduce a pregnant woman with pyogenic granuloma with a lesion on her face. CASE REPORT: The patient is a pregnant woman at 39 weeks of gestation without a history of a specific illness who referred to Shahid Akbarabadi Hospital in Tehran due to labor pain. A vascular nodule was visible on her face, which appeared from the first half of pregnancy and was reported to be normal in terms of paraclinical experiments. This vascular nodule improved after delivery but did not completely disappear. The patient underwent aesthetic surgery for the vascular nodule three months after delivery. The results of the pathology confirmed pyogenic granuloma. CONCLUSION: According to the results of this report, if unusual lesions are observed on the face during pregnancy, oral and dental problems should be considered and patients should be examined by the dentist