59 research outputs found

    Nonlinear Lattices Generated from Harmonic Lattices with Geometric Constraints

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    Geometrical constraints imposed on higher dimensional harmonic lattices generally lead to nonlinear dynamical lattice models. Helical lattices obtained by such a procedure are shown to be described by sine- plus linear-lattice equations. The interplay between sinusoidal and quadratic potential terms in such models is shown to yield localized nonlinear modes identified as intrinsic resonant modes

    Living Bacterial Sacrificial Porogens to Engineer Decellularized Porous Scaffolds

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    Decellularization and cellularization of organs have emerged as disruptive methods in tissue engineering and regenerative medicine. Porous hydrogel scaffolds have widespread applications in tissue engineering, regenerative medicine and drug discovery as viable tissue mimics. However, the existing hydrogel fabrication techniques suffer from limited control over pore interconnectivity, density and size, which leads to inefficient nutrient and oxygen transport to cells embedded in the scaffolds. Here, we demonstrated an innovative approach to develop a new platform for tissue engineered constructs using live bacteria as sacrificial porogens. E.coli were patterned and cultured in an interconnected three-dimensional (3D) hydrogel network. The growing bacteria created interconnected micropores and microchannels. Then, the scafold was decellularized, and bacteria were eliminated from the scaffold through lysing and washing steps. This 3D porous network method combined with bioprinting has the potential to be broadly applicable and compatible with tissue specific applications allowing seeding of stem cells and other cell types

    Tripod sign

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    "Tripod Sign" or "Amoss′s Sign" is a sign of meningeal irritation. Although useful in diagnosing meningitis, it is not pathognomic and may be seen in a variety of clinical conditions. Infants < 1 year of age and immunocompromised individuals may not demonstrate signs of meningeal irritation. Since elicitation of the sign requires voluntary sitting up, it is of limited use in patients with marked altered sensorium and young infants

    Hemolytic uremic syndrome associated with Plasmodium vivax malaria successfully treated with plasma exchange

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    We report a case of hemolytic uremic syndrome (HUS) in an adult patient with Plasmodium vivax malaria. The patient presented with worsening anemia, persistent thrombocytopenia and acute kidney injury. HUS was diagnosed based on the high serum lactate dehydrogenase, elevated reticulocyte count and presence of schistocytes on peripheral blood smear. Kidney biopsy showed features of thrombotic microangiopathy. Complete hematological remission was achieved after five sessions of therapeutic plasma exchange. Renal function partially recovered and stabilized at discharge. Vivax malaria, generally considered benign, may be rarely associated with HUS

    Intersection Collision Detection And Warning Protocol: Design Approach

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    Abstract -In recent years, the number of vehicles has increased dramatically. This causes a high traffic density and makes new security features a crucial point in order to keep the traffic safe. Developing automotive collision warning and avoidance systems will be very effective for reducing fatalities, injuries and associated costs. In order to develop an automotive collision warning and avoidance system, it is necessary that the vehicles should be able to exchange their dynamic information such as speed, acceleration, direction, relative position, etc. This paper presents a collision detection and warning protocol in intersection traffic controller (ITC) to improve the intelligent transportation systems (ITS) using a wireless communication technology. Each vehicle communicates with the ITC in real time to let the ITC know about its current location. The ITC includes this information in its message and warn the driver about the condition of the vehicle and the signal to avoid collision
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