Association between admission glucose and coronary collateral flow in ST-Elevation myocardial infarction patients

13th International Congress of Update in Cardiology and Cardiovascular Surgery (UCCVS) -- MAR 23-26, 2017 -- Cesme, TURKE

Nutritional status and severity of coronary artery disease

Objective The aim of this study is to evaluate the association between Nutritional Risk Index (NRI), a simple tool to assess nutritional status, and coronary artery disease severity and complexity in patients undergoing coronary angiography. Methods This study is a retrospective analysis of 822 patients undergoing coronary angiography. Patients with previous revascularization were excluded. Gensini and SYNTAX scores were calculated according to the angiographic images to determine atherosclerosis severity. NRI was calculated as follows: NRI = [15.19 × serum albumin (g/dl)] + [41.7 × (body weight/ideal body weight)]. In patients ≥65 years of age, Geriatric NRI (GNRI) was used instead of NRI. GNRI was calculated as follows: GNRI = [14.89 × serum albumin (g/dl)] + [41.7 × (body weight/ideal body weight)]. Patients were then divided into three groups as previously reported: NRI < 92, NRI 92–98 and NRI > 98. Gensini and SYNTAX scores were compared between three groups. Results The mean age of study population was 61.9 ± 11.1 years. NRI 98 was measured in 212, 321 and 289 patients, respectively. There was no difference regarding to sex, BMI, smoking, hypertension and diabetes mellitus between three groups. Patients with NRI < 92 had the highest mean Gensini score than the patients with NRI 92–98 and NRI > 98 (38.0 ± 40.6 vs. 31.17 ± 42.4 vs. 25.8 ± 38.4, P = 0.005). Also patients with NRI < 92 had the highest mean SYNTAX score than the patients with NRI 92–98 and NRI > 98 (11.8 ± 12.9 vs. 9.3 ± 12.4 vs. 7.7 ± 11.8, P = 0.001). Also, Gensini score of ≥20 and high SYNTAX score of ≥33 were associated with lower NRI (P < 0.001 and P < 0.001, respectively). Conclusion In our study, nutritional status evaluated by the NRI was associated with more extensive and complex coronary atherosclerosis in patients undergoing coronary angiography

Evaluation of the Efficacy and Safety of Oral İbuprofen in the Treatment of Patent Ductus Arteriosus

Since indomethacin has many side effects, ibuprofen has been started to be used with beneficial results and less side effects for the closure of patent ductus arteriosus (PDA) in recent years. The frequency of PDA, and the effects and side effects of oral ibuprofen were investigated by echocardiographic evaluation, in 164 preterm neonates in Neonatology Unit of Dicle University,between April and December 2004. Oral ibufrofen was given at 10 mg/kg/day dose to infants who had significant left-right shunt on the third day of birth but those who had contraindication for ibuprofen were excluded. By daily echocardiographic evaluations in those without closure after the first dose, a second and third dose of 5 mg/kg/day were given if necessary. Ductus closure has ocured in 24 of 27 (88.8%) patients, at a mean period of 1.7±0.9 (1-4) days. Complications like hyponatremia, hypercreatininemia, thrombocytopenia, and necrotizing enterocolitis were not seen. Only in one patient intracranial hemorrhage was occured two days after the treatment. In conclusion, treatment with oral ibuprofen is an effective and safe treatment method for the closure of the PDA in preterm infants

Digoxin Toxicity in a 14 Days Old Newborn: A Case Report

Digoxin is one of the most commonly used positive inotropic agent. Digitalis toxicity may occur easily because of digoxin has a narrow therapeutic window. Digitalis toxicity may result during treatment with digoxin or from accidental overdose of digoxin. An elevated serum level of digoxin (>2ng/ml) is likely to be associated with toxicity, overdose of digoxin (>5ng/ml) may lead to life-threatening arrhythmias. A 14-days old newborn with VSD, which had been prescribed the droplet form of digoxin but given the tablet form by the drugstore, was diagnosed as digitalis toxicity and hospitalized to our clinic. His mother expressed that she had given two tablets mashed with spoon and diluted. Bradycardia and grade 3/6 pansystolic murmur was determined in physical examination. Digoxin level in serum was >5 ng/ml and there was third degree atrioventricular block in ECG findings. The case has been presented to emphasize the importance of better evaluation of digoxin indications and making families of the patients conscious of the usage of digoxin

Atipik klinik ile tespit edilen atipik yerleşimli kardiyak miksoma

Atriyal miksomalar, en sık karşılaşılan benign primer kardiyak tümörlerdir. Literatürde tanımlandığı üzere birçok komplikasyona yol açmaktadır. Çoğunlukla solda atriyumda olsa da atriyum ve interatriyal septuma bağlı olarak, herhangi bir kardiyak boşlukta ortaya çıkabilir. Bu olgu raporunda 55 yaşındaki bir kadın hastamızı sunduk. Kardiyoloji polikliniğine tek taraflı geçici görme kaybı etyolojisinin araştırılması amacıyla danışıldı. Transözofageal-ekokardiyografide kardiyak miksoma olarak şüphe edilen bu kitlelenin cerrahi esnasında sol atriyum posteriyor duvar, sol üst pulmoner ven çevresinden kaynaklandığı tespit edildi ve kitle tamamen çıkartıldı. Patolojik inceleme sonucunda tanı kardiyak miksoma olarak doğrulandı. Geçici iskemik semptomları olan ancak atriyal fibrilasyonu olmayan hastalarda sol atriyumda potansiyel kitle tanısını koymak için ekokardiyografi yapılmalıdır.Atrial myxomas are the most common benign primary cardiac tumors that can lead to many complications as defined in literature. Although the majority occur in the left atrium and attached to interatrial septum, they can arise from any cardiac chamber. Here we report the case of a 55-year-old woman whom was referred to our outpatient clinic for etiological diagnosis of unilateral transient loss of vision. Transesophageal echocardiography revealed a mass that was suspected as cardiac myxoma arising from the posterior wall of the LA in the vicinity of the left superior pulmonary vein. During the surgical procedure cardiac mass was removed totally and the pathological examination confirmed the diagnosis as cardiac myxoma. In patients with transient ischaemic symptoms but without atrial fibrillation echocardiography should be performed to diagnose of potential mass in left atrium

Serum apolipoprotein e levels are higher in individuals with atherosclerotic coronary artery disease when compared to those without: presentation of preliminary findings

13th International Congress of Update in Cardiology and Cardiovascular Surgery (UCCVS) -- MAR 23-26, 2017 -- Cesme, TURKE