The ethos in the form making of grand projects in contemporary Beijing City

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 2004.Includes bibliographical references (leaves 80-81).Capital cities embody national identity and ethos, buildings in the capital cities have the power to awe and to inspire. While possibly no capital city in the world is being renewed so intensely as Beijing, which presents both enormous potential and threat. Intrinsic to this research is a concept that the design culture of a city is formed largely by the national character, aesthetic value and culture distinctive to that city; these are the soil of design culture which merit careful observation and description. The current architecture design in Beijing is by all means exploring the modern language appropriated in Chinese idioms, especially in significant public projects which are often sponsored by the government. In these projects, the cultural and social concerns intensively emerge together. Amidst these concerns, perceptions arise from the fields of professionals, clients and the mass, the three main representatives of design culture. Each of them is valid only to an extent which presents one dimension of the ethos. By studying three cases, National Theatre, CCTV Headquarter Office and National Stadium, we will identify the current cultural character and social value that may provide the soil of design culture in Beijing. Ultimately we would speculate on the potential development of architecture design in Beijing in the new century.by Keru Feng.S.M

Vascular risk factors for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

ObjectiveIdiopathic normal-pressure hydrocephalus (iNPH) is a treatable cause of dementia; however, its etiology and pathogenesis remain poorly understood. The objective of this study was to investigate the prevalence and impact of vascular risk factors in patients with iNPH compared to a control cohort to better understand the potential mechanisms and preventive measures.MethodsWe systematically searched PubMed, Web of Science, Embase, and the Cochrane Library (from inception to December 20, 2022) for studies reporting vascular risk factors for the development of iNPH. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using random-effects models.ResultsAfter screening 1,462 articles, 11 case-control studies comprising 1,048 patients with iNPH and 79,668 cognitively unimpaired controls were included in the meta-analysis. Our data showed that hypertension (N = 991, OR = 2.30, 95% CI 1.64 to 3.23, I2= 64.0%), diabetes mellitus (DM) (N = 985, OR = 3.12, 95% CI 2.29 to 4.27, I2= 44.0%), coronary heart disease (CHD; N = 880, OR = 2.34, 95% CI 1.33 to 4.12, I2= 83.1%), and peripheral vascular disease (N = 172, OR = 2.77, 95% CI 1.50 to 5.13, I2= 0.0%) increased the risk for iNPH, while overweight was a possible factor (N = 225, OR = 2.01, 95% CI 1.34 to 3.04, I2= 0.0%) based on the sensitivity analysis. Smoking and alcohol consumption were not associated with iNPH.ConclusionsOur study suggested that hypertension, DM, CHD, peripheral vascular disease, and overweight were associated with iNPH. These factors might be involved in the pathophysiological mechanisms promoting iNPH. These findings require further investigation in future studies.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, CRD42022383004

Peripheral blood CD19 positive B lymphocytes increase after ischemic stroke and correlate with carotid atherosclerosis

IntroductionAtherosclerosis is the primary pathological basis of ischemic stroke, and dyslipidemia is one of its major etiological factors. Acute ischemic stroke patients exhibit imbalances in lymphocyte subpopulations, yet the correlation between these dynamic changes in lymphocyte subpopulations and lipid metabolism disorders, as well as carotid atherosclerosis in stroke patients remains poorly understood.MethodsWe retrospectively analyzed the demographic data, risk factors of cerebrovascular disease, laboratory examination (lymphocyte subsets, lipid indexes, etc.), clinical features and c;/]-sity from December 2017 to September 2019 and non-stroke patients with dizziness/vertigo during the same period.ResultsThe results showed that peripheral B lymphocyte proportions are elevated in acute ischemic stroke patients compared with those of the control group (13.6 ± 5.3 vs. 11.7 ± 4.4%, p = 0.006). Higher B lymphocyte proportions are associated with concurrent dyslipidemia, increased levels of vascular risk factors including triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and very-low-density lipoprotein cholesterol (VLDL-C), as well as decreased levels of the protective factor high-density lipoprotein cholesterol (HDL-C). Elevated B lymphocyte proportions are independently correlated with carotid atherosclerosis in stroke patients.DiscussionWe found CD19 positive B Lymphocytes increase after ischemic stroke and correlate with Carotid Atherosclerosis. Lymphocyte subpopulations should be highlighted in stroke patients

Experimental Study on the Influence of a Two-Dimensional Cosine Hill on Wind Turbine Wake

The accurate prediction of wind energy distribution on the terrain has been of great significance for wind farm selection. Therefore, this paper evaluated the influence of a two-dimensional hill with a relatively large slope (i.e., 0.83) on wind turbine wake. Firstly, the wakes on flat terrain and wind characteristics around a single hill were investigated by using a hot-wire anemometer. Subsequently, wake distributions combined with the hill were measured when the turbine was located 2D in front and on the hilltop. The results of the hill showed that a flow separation was formed within 6D of the leeward side (where D is the rotor diameter). The turbulence intensity increased initially and then decreased as height increased, leading to a high turbulence region 2.28 times the hill height, according to the experiment of a wind turbine combined with the hill. In conclusion, wake recovery was promoted on the windward side and 4D behind the hilltop. As the longitudinal coordinate increased, the intensity of the turbulence changed to a single peak, and the peak value was more than twice as high as on flat terrain. Based on this, it may be possible to optimize the design of wind turbines for better performance

Experimental Study on the Influence of a Two-Dimensional Cosine Hill on Wind Turbine Wake

The accurate prediction of wind energy distribution on the terrain has been of great significance for wind farm selection. Therefore, this paper evaluated the influence of a two-dimensional hill with a relatively large slope (i.e., 0.83) on wind turbine wake. Firstly, the wakes on flat terrain and wind characteristics around a single hill were investigated by using a hot-wire anemometer. Subsequently, wake distributions combined with the hill were measured when the turbine was located 2D in front and on the hilltop. The results of the hill showed that a flow separation was formed within 6D of the leeward side (where D is the rotor diameter). The turbulence intensity increased initially and then decreased as height increased, leading to a high turbulence region 2.28 times the hill height, according to the experiment of a wind turbine combined with the hill. In conclusion, wake recovery was promoted on the windward side and 4D behind the hilltop. As the longitudinal coordinate increased, the intensity of the turbulence changed to a single peak, and the peak value was more than twice as high as on flat terrain. Based on this, it may be possible to optimize the design of wind turbines for better performance

Assessing Growth and Water Productivity for Drip-Irrigated Maize under High Plant Density in Arid to Semi-Humid Climates

Determining the water productivity of maize is of great significance for ensuring food security and coping with climate change. In 2018 and 2019, we conducted field trials in arid areas (Changji), semi-arid areas (Qitai) and semi-humid areas (Xinyuan). The hybrid XY335 was selected for the experiment, the planting density was 12.0 × 104 plants ha−1, and five irrigation amounts were set. The results showed that yield, biomass, and transpiration varied substantially and significantly between experimental sites, irrigation and years. Likewise, water use efficiency (WUE) for both biomass (WUEB) and yield (WUEY) were affected by these factors, including a significant interaction. Normalized water productivity (WP*) of maize increased significantly with an increase in irrigation. The WP* for film mulched drip irrigation maize was 37.81 g m−2 d−1; it was varied significantly between sites and irrigation or their interaction. We conclude that WP* differs from the conventional parameter for water productivity but is a useful parameter for assessing the attainable rate of film-mulched drip irrigation maize growth and yield in arid areas, semi-arid areas and semi-humid areas. The parametric AquaCrop model was not accurate in simulating soil water under film mulching. However, it was suitable for the prediction of canopy coverage (CC) for most irrigation treatments

Assessing Growth and Water Productivity for Drip-Irrigated Maize under High Plant Density in Arid to Semi-Humid Climates

Determining the water productivity of maize is of great significance for ensuring food security and coping with climate change. In 2018 and 2019, we conducted field trials in arid areas (Changji), semi-arid areas (Qitai) and semi-humid areas (Xinyuan). The hybrid XY335 was selected for the experiment, the planting density was 12.0 × 104 plants ha−1, and five irrigation amounts were set. The results showed that yield, biomass, and transpiration varied substantially and significantly between experimental sites, irrigation and years. Likewise, water use efficiency (WUE) for both biomass (WUEB) and yield (WUEY) were affected by these factors, including a significant interaction. Normalized water productivity (WP*) of maize increased significantly with an increase in irrigation. The WP* for film mulched drip irrigation maize was 37.81 g m−2 d−1; it was varied significantly between sites and irrigation or their interaction. We conclude that WP* differs from the conventional parameter for water productivity but is a useful parameter for assessing the attainable rate of film-mulched drip irrigation maize growth and yield in arid areas, semi-arid areas and semi-humid areas. The parametric AquaCrop model was not accurate in simulating soil water under film mulching. However, it was suitable for the prediction of canopy coverage (CC) for most irrigation treatments

Is the inherent potential of maize roots efficient for soil phosphorus acquisition?

Sustainable agriculture requires improved phosphorus (P) management to reduce the overreliance on P fertilization. Despite intensive research of root adaptive mechanisms for improving P acquisition, the inherent potential of roots for efficient P acquisition remains unfulfilled, especially in intensive agriculture, while current P management generally focuses on agronomic and environmental concerns. Here, we investigated how levels of soil P affect the inherent potential of maize (Zea mays L.) roots to obtain P from soil. Responses of root morphology, arbuscular mycorrhizal colonization, and phosphate transporters were characterized and related to agronomic traits in pot and field experiments with soil P supply from deficiency to excess. Critical soil Olsen-P level for maize growth approximated 3.2 mg kg(-1), and the threshold indicating a significant environmental risk was about 15 mg kg(-1), which represented the lower and upper levels of soil P recommended in current P management. However, most root adaptations involved with P acquisition were triggered when soil Olsen-P was below 10 mg kg(-1), indicating a threshold for maximum root inherent potential. Therefore, to maintain efficient inherent potential of roots for P acquisition, we suggest that the target upper level of soil P in intensive agriculture should be reduced from the environmental risk threshold to the point maximizing the inherent potential of roots

Radiometric Correction of Multispectral Field Images Captured under Changing Ambient Light Conditions and Applications in Crop Monitoring

Applications of unmanned aerial vehicle (UAV) spectral systems in precision agriculture require raw image data to be converted to reflectance to produce time-consistent, atmosphere-independent images. Complex light environments, such as those caused by varying weather conditions, affect the accuracy of reflectance conversion. An experiment was conducted here to compare the accuracy of several target radiance correction methods, namely pre-calibration reference panel (pre-CRP), downwelling light sensor (DLS), and a novel method, real-time reflectance calibration reference panel (real-time CRP), in monitoring crop reflectance under variable weather conditions. Real-time CRP used simultaneous acquisition of target and CRP images and immediate correction of each image. These methods were validated with manually collected maize indictors. The results showed that real-time CRP had more robust stability and accuracy than DLS and pre-CRP under various conditions. Validation with maize data showed that the correlation between aboveground biomass and vegetation indices had the least variation under different light conditions (correlation all around 0.74), whereas leaf area index (correlation from 0.89 in sunny conditions to 0.82 in cloudy days) and canopy chlorophyll content (correlation from 0.74 in sunny conditions to 0.67 in cloudy days) had higher variation. The values of vegetation indices TVI and EVI varied little, and the model slopes of NDVI, OSAVI, MSR, RVI, NDRE, and CI with manually measured maize indicators were essentially constant under different weather conditions. These results serve as a reference for the application of UAV remote sensing technology in precision agriculture and accurate acquisition of crop phenotype data

The Effect and Mechanism of KLF7 in the TLR4/NF-κB/IL-6 Inflammatory Signal Pathway of Adipocytes

Objective. To investigate the role and possible molecular mechanism of Krüppel-like factor 7 (KLF7) in the TLR4/NF-κB/IL-6 inflammatory signaling pathway activated by free fatty acids (FFA). Methods. The mRNA and protein expression levels of KLF7 and the factors of TLR4/NF-κB/IL-6 inflammatory signal pathways were detected by qRT-PCR and Western blotting after cell culture with different concentrations of palmitic acid (PA). The expression of KLF7 or TLR4 in adipocytes was upregulated or downregulated; after that, the mRNA and protein expression levels of these key factors were detected. KLF7 expression was downregulated while PA stimulated adipocytes, and then the mRNA and protein expressions of KLF7/p65 and downstream inflammatory cytokine IL-6 were detected. The luciferase reporter assay was used to determine whether KLF7 had a transcriptional activation effect on IL-6. Results. (1) High concentration of PA can promote the expression of TLR4, KLF7, and IL-6 in adipocytes. (2) TLR4 positively regulates KLF7 expression in adipocytes. (3) KLF7 positively regulates IL-6 expression in adipocytes. (4) PA promotes IL-6 expression via KLF7 in adipocytes. (5) KLF7 has a transcriptional activation on IL-6. Conclusion. PA promotes the expression of the inflammatory cytokine IL-6 by activating the TLR4/KLF7/NF-κB inflammatory signaling pathway. In addition, KLF7 may directly bind to the IL-6 promoter region and thus activate IL-6