14 research outputs found

    Steroid Sensitive Pain Associated with a Retro-Orbital Mass

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    Blurred central vision; Deep right retro-orbital painA 47-year old female with a 12-day history of blurred central vision OD accompanied by pain on motion and deep right retro-orbital pain.VA: 20/400 OD, 20/30 OSNeoplastic plasma cellsCorticosteroids; Surgery; XRTMoossy, J., Wilson, C.B.: Solitary intracranial ... Arch Neurol 16: 212, Feb 1967

    Idiopathic sclerosing inflammation of the orbit: A case of steroid-responsive disease in a patient with autoimmune hemolytic anemia

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    Purpose: Idiopathic sclerosing orbital inflammation (ISOI) has been categorized by some authors as a unique clinicopathologic entity, separate from the heterogenous group of disorders known collectively as nonspecific orbital inflammation. Histologic similarity and clinical association with other fibrosclerosing conditions has been shown. The authors present a case of ISOI in conjunction with autoimmune hemolytic anemia. Methods: A 59-year-old woman with a history of hemolytic anemia had left upper lid swelling, periocular pain, proptosis, and restriction of ocular motility. Magnetic resonance imaging (MRI) showed a homogenously enhancing lateral orbital mass. Biopsy revealed dense fibrous connective tissue with a paucicellular infiltrate, consistent with ISOI, and treatment with prednisolone 60 mg/day was instituted. Results: At 4-week review, the proptosis had settled and the patient regained full range of extraocular movements. At 14 months, the response was sustained and repeat MRI showed a 70% reduction in size of the mass. Conclusions. The first known case of ISOI and hemolytic anemia is presented. Despite dense fibrosis histologically, steroid responsiveness can be encountered in cases of ISOI. An early, aggressive approach to management is recommended, and corticosteroids should be considered as a treatment option.K.J. Billing, J. Hsuan and D. Selv
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