31 research outputs found

    Delivering safe and effective test-result communication, management and follow-up : a mixed-methods study protocol

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    Introduction: The failure to follow-up pathology and medical imaging test results poses patient-safety risks which threaten the effectiveness, quality and safety of patient care. The objective of this project is to: (1) improve the effectiveness and safety of test-result management through the establishment of clear governance processes of communication, responsibility and accountability; (2) harness health information technology (IT) to inform and monitor test-result management; (3) enhance the contribution of consumers to the establishment of safe and effective test-result management systems. Methods and analysis: This convergent mixed-methods project triangulates three multistage studies at seven adult hospitals and one paediatric hospital in Australia. Study 1 adopts qualitative research approaches including semistructured interviews, focus groups and ethnographic observations to gain a better understanding of test-result communication and management practices in hospitals, and to identify patient-safety risks which require quality-improvement interventions. Study 2 analyses linked sets of routinely collected healthcare data to examine critical test-result thresholds and test-result notification processes. A controlled before-and-after study across three emergency departments will measure the impact of interventions (including the use of IT) developed to improve the safety and quality of test-result communication and management processes. Study 3 adopts a consumer-driven approach, including semistructured interviews, and the convening of consumer-reference groups and community forums. The qualitative data will identify mechanisms to enhance the role of consumers in test-management governance processes, and inform the direction of the research and the interpretation of findings. Ethics and dissemination: Ethical approval has been granted by the South Eastern Sydney Local Health District Human Research Ethics Committee and Macquarie University. Findings will be disseminated in academic, industry and consumer journals, newsletters and conferences

    Cell motion predicts human epidermal stemness

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    Image-based identification of cultured stem cells and noninvasive evaluation of their proliferative capacity advance cell therapy and stem cell research. Here we demonstrate that human keratinocyte stem cells can be identified in situ by analyzing cell motion during their cultivation. Modeling experiments suggested that the clonal type of cultured human clonogenic keratinocytes can be efficiently determined by analysis of early cell movement. Image analysis experiments demonstrated that keratinocyte stem cells indeed display a unique rotational movement that can be identified as early as the two-cell stage colony. We also demonstrate that α6 integrin is required for both rotational and collective cell motion. Our experiments provide, for the first time, strong evidence that cell motion and epidermal stemness are linked. We conclude that early identification of human keratinocyte stem cells by image analysis of cell movement is a valid parameter for quality control of cultured keratinocytes for transplantation

    Delivering safe and effective test-result communication, management and follow-up: A mixed-methods study protocol

    Get PDF
    IntroductionThe failure to follow-up pathology and medical imaging test results poses patient-safety risks which threaten the effectiveness, quality and safety of patient care. The objective of this project is to: (1) improve the effectiveness and safety of test-result management through the establishment of clear governance processes of communication, responsibility and accountability; (2) harness health information technology (IT) to inform and monitor test-result management; (3) enhance the contribution of consumers to the establishment of safe and effective test-result management systems.Methods and analysisThis convergent mixed-methods project triangulates three multistage studies at seven adult hospitals and one paediatric hospital in Australia.Study 1 adopts qualitative research approaches including semistructured interviews, focus groups and ethnographic observations to gain a better understanding of test-result communication and management practices in hospitals, and to identify patient-safety risks which require quality-improvement interventions.Study 2 analyses linked sets of routinely collected healthcare data to examine critical test-result thresholds and test-result notification processes. A controlled before-and-after study across three emergency departments will measure the impact of interventions (including the use of IT) developed to improve the safety and quality of test-result communication and management processes.Study 3 adopts a consumer-driven approach, including semistructured interviews, and the convening of consumer-reference groups and community forums. The qualitative data will identify mechanisms to enhance the role of consumers in test-management governance processes, and inform the direction of the research and the interpretation of findings

    A road map for designing and implementing a biological monitoring program

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    Designing and implementing natural resource monitoring is a challenging endeavor undertaken by many agencies, NGOs, and citizen groups worldwide. Yet many monitoring programs fail to deliver useful information for a variety of administrative (staffing, documentation, and funding) or technical (sampling design and data analysis) reasons. Programs risk failure if they lack a clear motivating problem or question, explicit objectives linked to this problem or question, and a comprehensive conceptual model of the system under study. Designers must consider what “success” looks like from a resource management perspective, how desired outcomes translate to appropriate attributes to monitor, and how they will be measured. All such efforts should be filtered through the question “Why is this important?” Failing to address these considerations will produce a program that fails to deliver the desired information. We addressed these issues through creation of a “road map” for designing and implementing a monitoring program, synthesizing multiple aspects of a monitoring program into a single, overarching framework. The road map emphasizes linkages among core decisions to ensure alignment of all components, from problem framing through technical details of data collection and analysis, to program administration. Following this framework will help avoid common pitfalls, keep projects on track and budgets realistic, and aid in program evaluations. The road map has proved useful for monitoring by individuals and teams, those planning new monitoring, and those reviewing existing monitoring and for staff with a wide range of technical and scientific skills

    Grace Roots : Forty Days of Grace

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    Buku ini dibuat untuk memberikan anda kelimpahan kasih karunia Allah. Banyak orang mencoba hidup menjadi orang kristen yang baik, yang memikul kuk yang Tuhan pasang, namun mengapa mereka merasa kekosongan dan tetap dahaga? Buku ini akan memberikan penjelasan dan ilustrasi mengenai anugerah Allah.159 p. ; 21 c

    Perjanjian Baru, Kemuliaan Baru

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    Buku ini ditulis untuk membagikan dan mengimpartasikan kebenaran mengenai apa yang telah Tuhan capai untuk anda dan siapa anda di dalam DIA-kebenaran yang membebaskan anda.ix, 175 p. ; 21 c

    New Covenant, New Glory

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    Perjanjian: perjanjian yang dibuat antara dua pihak dengan tujuan membangun hubungan di antara mereka. Lantas, apa yang Tuhan tempatkan sebagai landasan hubungan kita dengan-Nya? Atas dasar apa kita diterima dan diberkati Tuhan? Banyak orang Kristen yang masih berusaha berhubungan dengan Tuhan berdasarkan perjanjian yang sudah tidak ada lagi! Namun mereka tidak perlu lagi berjuang dan bekerja di bawah kutukan. Di bawah perjanjian baru, orang-orang percaya adalah pewaris kekayaan rohani yang tak terhitung jumlahnya! Namun, jika kita tidak mengetahui warisan yang diberikan Allah, berarti meskipun kita kaya, kita akan hidup dalam kemiskinan rohani. Perjanjian Baru, Kemuliaan Baru akan membantu membebaskan Anda dari pemikiran perjanjian lama yang mencoba membuat Anda membayar atas apa yang telah diberikan secara cuma-cuma kepada Anda melalui kasih karunia. Kemuliaan perjanjian lama adalah kemuliaan yang memudar. Sebaliknya, kemuliaan perjanjian baru semakin terang. Di mana pun Anda berada dalam perjalanan kekristenan Anda, masih ada kemuliaan yang lebih besar.127 p. ; 21 c

    Grace: The Power to Reign: God's Ability in the Place of Your Inability

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    Buku ini membahas tentang kasih karunia (grace) dalam konteks kehidupan Kristen dan bagaimana kekuatan Allah bekerja di tempat kelemahan manusia. Sayangnya, informasi lebih lanjut tentang isi buku tidak tersedia.ix, 117 p. ; 23 c

    It's Not What You Eat That's Making You Sick, But What's Eating You?

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    Buku ini membahas tentang aspek psikologi di pandangan agama Kristen. Mencakup kesehatan mental dan self-actualization yang dilihat dari sudut pandang agama.160 p. ; 21 c
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