Composite Oncocytoma and Papillary Renal Cell Carcinoma of the Kidney Treated by Partial Nephrectomy: A Case Report

We present the case of a 73-year-old woman who presented with lethargy and a nonproductive cough. Computerised tomography of her abdomen revealed a 38-mm mass in the lower pole of her left kidney. She underwent a partial nephrectomy, with final histopathological analysis confirming the presence of a concomitant oncocytoma and papillary cell carcinoma. To our knowledge, this is the only case report in the world literature describing a papillary renal cell carcinoma within an oncocytoma treated by partial nephrectomy

An unusual case of low-grade tubulopapillary adenocarcinoma of the sinonasal tract

<p>Abstract</p> <p>Background</p> <p>Low-grade papillary adenocarcinomas of the sinonasal tract are rare neoplasms. Over recent years, little doubt remains that this tumour represents a separate entity based on morphology, ultrastructural features and behaviour. We outline a case of this rare entity displaying a not hitherto described immunophenotype.</p> <p>Case presentation</p> <p>A 32 year old man presented recurrent epistaxis was evaluated with endoscopy which revealed a well circumscribed pedunculated mass lesion in left nares. The mass was arising from the nasal septum which was excised along with the mass. The biopsy revealed low-grade, non-intestinal type sinonasal tubulopapillary adenocarcinoma.</p> <p>Conclusion</p> <p>TTF-1 immunoreactivity in absence of thyroid or pulmonary primary in the present case remains an enigma. However, this raises the possibility of the utility of this antibody to predict a better clinical outcome in the subset of low grade non-intestinal sinonasal adenocarcinoma. More cases of similar morphological appearance may need to be examined for TTF-1 immunoreactivity and clinically followed up to establish this theory.</p