We Are Roses From Our Mothers\u27 Gardens: Black Feminist Visuality in African American Women\u27s Art

ABSTRACT WE ARE ROSES FROM OUR MOTHERS’ GARDENS: BLACK FEMINIST VISUALITY IN AFRICAN AMERICAN WOMEN’S ART MAY 2017 KELLI MORGAN, B.A., WAYNE STATE UNIVERSITY M.A., UNIVERSITY OF MASSACHUSETTS AMHERST Ph.D., UNIVERISTY OF MASSACHUSETTS AMHERST Directed by: Professor Manisha Sinha We Are Roses From Our Mothers\u27 Gardens posits that in differing historical periods African American women visual artists employed various media and create from individual political thoughts, intellectual views, and aesthetic interests to emphasize the innate unification of a Black woman’s race, gender, sexuality, class, and selfhood and how this multifaceted dynamic of Black women’s identity and material reality produces a unique, multilayered form of oppression experienced only by Black women. Their diverse expressions of multilayered, figurative works acknowledge and address how the synthesis of racism, sexism, and patriarchy has been both mercurial and fixed throughout Black women’s existence in the United States. Thus, the dissertation argues that multilayered, figurative works of art by African American women artists are connected across time through Black feminist visuality, a creative imaging of Black women’s self-making, autonomy, subjectivity, and personal empowerment that allows them to transcend the distorted, mythological constructions of Black female identity concretized within western visual culture as it reveals the functions of western culture’s racist visuality and rejects its subjugation of Black women’s identity formation. Its sub-theory of visible-aggregation illustrates how Black feminist visuality exists among African American women artists as a shared self-defined standpoint of representing Black women’s identity and material reality in western visual art. Through a close reading of works by Sojourner Truth, Edmonia Lewis, Elizabeth Catlett, and Kara Walker the project demonstrates how African American women artists utilize visible-aggregation to express Black feminist visuality through multilayered, figurative art forms that exist as optical illustrations of Black feminism in the western visual realm

Is Your School Prepared for a Sexting Crisis?

Sexting is a growing challenge. Results from a survey indicated that 20% of adolescents ages 13–19 have sent or posted nude or semi-nude pictures of themselves; 71% of adolescent females and 67% of adolescent males who have sexted sent the content to a boyfriend or girlfriend; and 38% of adolescent females and 39% of adolescent males report having seen messages originally intended for someone else (National Campaign, 2008). Those messages can spread at a rapid rate, causing both legal and emotional ramifications for all students involved. Principals can help prevent sexting and mitigate its negative consequences by making staff members and students aware of the issues involved and implementing effective prevention and intervention efforts

A new sex-specific genetic marker (fshr 1834G>T) for flathead grey mullet, Mugil cephalus, in Queensland, Australia

In this study, genetic sex marker candidates from northern hemisphere Mugil cephalus were tested to see if they could be used to sex a population originating from south-east Queensland, Australia. As such, a region of the follicle stimulating hormone receptor (fshr) gene was sequenced but did not contain previously published single nucleotide polymorphisms (SNPs). However, further screening of the sequenced fshr region revealed a promising sex marker candidate for Queensland M. cephalus, fshr 1834 G>T, which was accurate in 100% of fish tested (excluding intersex fish, which had the female genotype). While all females tested were homozygous G/G, males presented as either G/T (common) or T/T (lower frequency). Subsequently, a real-time high-resolution melt was developed to facilitate rapid and accurate genotyping of M. cephalus based on the fshr 1834 G>T SNP. Initial results suggest that fshr 1834 G>T is a useful SNP that can reduce the need for more invasive sampling techniques such as gonadal biopsy, provide information relating to the sex of captive stock prior to gonadal maturation, and may prove useful in wild population surveys and stock assessment

Sexting: You Found the Sext, What to Do Next? How School Psychologists Can Assist with Policy, Prevention, and Intervention

Early Monday morning, it is brought to the school psychologist’s attention that Katie, a 15-year-old student, engaged in “sexting” over the weekend; she sent a naked picture of herself to her boyfriend. The boyfriend immediately forwarded the picture to a group of his friends. At school on Monday, many students were talking about the picture, and Katie was humiliated. The school is unaware of how many students this sext message has reached. What can the school psychologist do to intervene with the female student, her boyfriend, and his friends? What, if anything, can be done to prevent this message from being spread to other students and even other school districts? Should law enforcement be contacted? How can the school psychologist help prevent similar incidents from occurring in the future

Peeling the Paint off the Walls: Kelli Morgan on Black Performance and Racial Justice in Western Institutions

In this conversation with editors Hanna B. Hölling, Jules Pelta Feldman, and Emilie Magnin, Kelli Morgan—critical race scholar, curator, educator, and social justice activist—discusses the challenges related to Western conceptions of institutions and their underpinning values. Addressing the colonialist roots of modern museums, Morgan talks about the challenges she has faced as a Black woman in several U.S. American museums; emphasizes the importance of creating change in museum collections (rather than only in temporary exhibitions); considers alternative practices for conserving art and knowledge; and explains her efforts to address these problems in her pedagogy

Large Fatty Acid-Derived Aβ42 Oligomers Form Ring-Like Assemblies

As the primary toxic species in the etiology of Alzheimer disease (AD) are low molecular weight oligomers of Aβ, it is crucial to understand the structure of Aβ oligomers for gaining molecular insights into AD pathology. We have earlier demonstrated that in the presence of fatty acids, Aβ42 peptides assemble as 12-24mer oligomers. These Large Fatty Acid-derived Oligomers (LFAOs) exist predominantly as 12mers at low and as 24mers at high concentrations. The 12mers are more neurotoxic than the 24mers and undergo self-replication, while the latter propagate to morphologically distinct fibrils with succinct pathological consequences. In order to glean into their functional differences and similarities, we have determined their structures in greater detail by combining molecular dynamic simulations with biophysical measurements. We conjecture that the LFAO are made of Aβ units in an S-shaped conformation, with the 12mers forming a double-layered hexamer ring (6 × 2) while the structure of 24mers is a double-layered dodecamer ring (12 × 2). A closer inspection of the (6 × 2) and (12 × 2) structures reveals a concentration and pH dependent molecular reorganization in the assembly of 12 to 24mers, which seems to be the underlying mechanism for the observed biophysical and cellular properties of LFAOs

Biophysical Characteristics of Lipid-Induced Aβ Oligomers Correlate to Distinctive Phenotypes In Transgenic Mice

Alzheimer\u27s disease (AD) is a progressive neurodegenerative disorder that affects cognition and memory. Recent advances have helped identify many clinical sub-types in AD. Mounting evidence point toward structural polymorphism among fibrillar aggregates of amyloid-β (Aβ) to being responsible for the phenotypes and clinical manifestations. In the emerging paradigm of polymorphism and prion-like propagation of aggregates in AD, the role of low molecular weight soluble oligomers, which are long known to be the primary toxic agents, in effecting phenotypes remains inconspicuous. In this study, we present the characterization of three soluble oligomers of Aβ42, namely 14LPOs, 16LPOs, and GM1Os with discreet biophysical and biochemical properties generated using lysophosphatidyl glycerols and GM1 gangliosides. The results indicate that the oligomers share some biophysical similarities but display distinctive differences with GM1Os. Unlike the other two, GM1Os were observed to be complexed with the lipid upon isolation. It also differs mainly in detection by conformation-sensitive dyes and conformation-specific antibodies, temperature and enzymatic stability, and in the ability to propagate morphologically-distinct fibrils. GM1Os also show distinguishable biochemical behavior with pronounced neuronal toxicity. Furthermore, all the oligomers induce cerebral amyloid angiopathy (CAA) and plaque burden in transgenic AD mice, which seems to be a consistent feature among all lipid-derived oligomers, but 16LPOs and GM1Os displayed significantly higher effect than the others. These results establish a correlation between molecular features of Aβ42 oligomers and their distinguishable effects in transgenic AD mice attuned by lipid characteristics, and therefore help bridge the knowledge gap in understanding how oligomer conformers could elicit AD phenotypes

Treating Early-Stage CKD With New Medication Therapies:Results of a CKD Patient Survey Informing the 2020 NKF-FDA Scientific Workshop on Clinical Trial Considerations for Developing Treatments for Early Stages of Common, Chronic Kidney Diseases

RATIONALE & OBJECTIVE: With a growing number of medications and therapies available to treat chronic kidney disease (CKD), risk-versus-benefit discussions are increasingly critical. Balancing risks and benefits requires assessing patients’ understanding of these, as well as incorporating patient preferences and tolerance for side effects into shared decision making. STUDY DESIGN: A 26-question online survey was sent to people in the National Kidney Foundation patient email list and posted on associated social media pages to assess the respondents’ willingness and comfort with taking preventative medications during earlier-stage CKD to inform a December 2020 scientific workshop co-sponsored by the National Kidney Foundation and the US Food and Drug Administration on clinical trial considerations in developing treatments for individuals with early stages of CKD. SETTING & POPULATION: Online survey of CKD patients, including broad demographic data and responses to risk-benefit scenarios, with surveys emailed to 20,249 people not identified as currently receiving kidney replacement therapy. ANALYTICAL APPROACH: Survey results are presented as descriptive data. RESULTS: Of 1,029 respondents, 45 self-identified as at risk for CKD, 566 had CKD, 267 had received kidney transplants, 51 were receiving dialysis, and 100 replied other or did not answer. Respondents reported being willing to assume some risk with the goal of preventing the progression of CKD, with a greater willingness to assume risk and treatment burdens the closer they came to late-stage disease. Clinician recommendations regarding kidney therapies and clinician willingness to work with patients to address any side effects were important in respondents’ willingness to initiate and persevere with a new medication. LIMITATIONS: Approximately 10% response rate with limited data on respondents. CONCLUSIONS: Risk-versus-benefit discussions appear key to patients and their care partners making well-informed decisions about taking a new medication that may or may not help the progression of their kidney disease. Future tools and strategies are needed to facilitate informed discussions of treatment in early-stage kidney disease

Sensor-as-a-Service: Convergence of Sensor Analytic Point Solutions (SNAPS) and Pay-A-Penny-Per-Use (PAPPU) Paradigm as a Catalyst for Democratization of Healthcare in Underserved Communities

In this manuscript, we discuss relevant socioeconomic factors for developing and implementing sensor analytic point solutions (SNAPS) as point-of-care tools to serve impoverished communities. The distinct economic, environmental, cultural, and ethical paradigms that affect economically disadvantaged users add complexity to the process of technology development and deployment beyond the science and engineering issues. We begin by contextualizing the environmental burden of disease in select low-income regions around the world, including environmental hazards at work, home, and the broader community environment, where SNAPS may be helpful in the prevention and mitigation of human exposure to harmful biological vectors and chemical agents. We offer examples of SNAPS designed for economically disadvantaged users, specifically for supporting decision-making in cases of tuberculosis (TB) infection and mercury exposure. We follow-up by discussing the economic challenges that are involved in the phased implementation of diagnostic tools in low-income markets and describe a micropayment-based systems-as-a-service approach (pay-a-penny-per-use—PAPPU), which may be catalytic for the adoption of low-end, low-margin, low-research, and the development SNAPS. Finally, we provide some insights into the social and ethical considerations for the assimilation of SNAPS to improve health outcomes in marginalized communities

A Multi-City Comparison of Front and Backyard Differences in Plant Species Diversity and Nitrogen Cycling in Residential landscapes

We hypothesize that lower public visibility of residential backyards reduces households’ desire for social conformity, which alters residential land management and produces differences in ecological composition and function between front and backyards. Using lawn vegetation plots (7 cities) and soil cores (6 cities), we examine plant species richness and evenness and nitrogen cycling of lawns in Boston, Baltimore, Miami, Minneapolis-St. Paul, Phoenix, Los Angeles (LA), and Salt Lake City (SLC). Seven soil nitrogen measures were compared because different irrigation and fertilization practices may vary between front and backyards, which may alter nitrogen cycling in soils. In addition to lawn-only measurements, we collected and analyzed plant species richness for entire yards—cultivated (intentionally planted) and spontaneous (self-regenerating)—for front and backyards in just two cities: LA and SLC. Lawn plant species and soils were not different between front and backyards in our multi-city comparisons. However, entire-yard plant analyses in LA and SLC revealed that frontyards had significantly fewer species than backyards for both cultivated and spontaneous species. These results suggest that there is a need for a more rich and social-ecologically nuanced understanding of potential residential, household behaviors and their ecological consequences