8 research outputs found
<i>Itai-itai</i> disease: Lessons from the investigations of environmental epidemiology conducted in the 1970’s, with special reference to the studies of the Toyama Institute of Health
No full textThe gender differences in health effects of environmental cadmium exposure and potential mechanisms
No full textOn a viewpoint of gender differences in Cd body burden and its health effects, we reviewed the population- based research including our own which conducted in Japan, Thailand, Australia, Poland, Belgium and Sweden to assess health effects of human exposure to environmental cadmium and their potential mechanisms. As a result, six risk factors in Cd health effects in women have been identified; ( 1) more serious type of renal tubular dysfunction, ( 2) difference in calcium metabolism and its regulatory hormones, ( 3) kidney sensitivity; difference in P450 phenotype, ( 4) pregnancy, ( 5) body iron store status, and ( 6) genetic factors. Further studies of Cd toxicity targeted to women would now appear necessary
