228 research outputs found
Joint IterativeTx/Rx MMSE-FDE and ISICancellation for Single-Carrier Hybrid ARQ with Chase Combining
Masking and Mixing Adversarial Training
While convolutional neural networks (CNNs) have achieved excellent
performances in various computer vision tasks, they often misclassify with
malicious samples, a.k.a. adversarial examples. Adversarial training is a
popular and straightforward technique to defend against the threat of
adversarial examples. Unfortunately, CNNs must sacrifice the accuracy of
standard samples to improve robustness against adversarial examples when
adversarial training is used. In this work, we propose Masking and Mixing
Adversarial Training (M2AT) to mitigate the trade-off between accuracy and
robustness. We focus on creating diverse adversarial examples during training.
Specifically, our approach consists of two processes: 1) masking a perturbation
with a binary mask and 2) mixing two partially perturbed images. Experimental
results on CIFAR-10 dataset demonstrate that our method achieves better
robustness against several adversarial attacks than previous methods
Data-driven Exploration of New Pressure-induced Superconductivity in PbBiTe with Two Transition Temperatures
Candidates compounds for new thermoelectric and superconducting materials,
which have narrow band gap and flat bands near band edges, were exhaustively
searched by the high-throughput first-principles calculation from an inorganic
materials database named AtomWork. We focused on PbBiTe which has the
similar electronic band structure and the same crystal structure with those of
a pressure-induced superconductor SnBi2Se4 explored by the same data-driven
approach. The PbBiTe was successfully synthesized as single crystals
using a melt and slow cooling method. The core level X-ray photoelectron
spectroscopy analysis revealed Pb2+, Bi3+ and Te2- valence states in
PbBiTe. The thermoelectric properties of the PbBiTe sample were
measured at ambient pressure and the electrical resistivity was also evaluated
under high pressure using a diamond anvil cell with boron-doped diamond
electrodes. The resistivity decreased with increase of the pressure, and two
pressure-induced superconducting transitions were discovered at 3.4 K under
13.3 GPa and at 8.4 K under 21.7 GPa. The data-driven approach shows promising
power to accelerate the discovery of new thermoelectric and superconducting
materials
Magnetocaloric and Magnetic Properties of MetaâMagnetic Heusler Alloy Ni41Co9Mn31.5Ga18.5
Ni41Co9Mn31.5Ga18.5 is a magnetic Heusler alloy, which indicates metamagnetic transition at the reverse martensite transition. In this paper, caloric measurements were performed and discussed about magnetocaloric effect. We also performed magnetization measurements around Curie temperature TC in the martensite phase and analyzed by means of the spin fluctuation theory of itinerant electron magnetism. From the differential scanning calorimetry (DSC) measurements in zero fields, the value of the latent heat λ was obtained as 2.63 kJ/kg, and in magnetic fields the value was not changed. The entropy change ÎS was â 7.0 J/(kgK) in zero fields and gradually increases with increasing magnetic fields. The relative cooling power (RCP) was 104 J/kg at 2.0 T, which was comparable with In doped Ni41Co9Mn32Ga16In2 alloy
Amino acid alterations in Gag that confer the ability to grow in simian cells on HIV-1 are located at a narrow CA region
We previously generated a prototype monkey-tropic human immunodeficiency virus type 1 (HIV-1) designated NL-DT5R. This viral clone has a small region of simian immunodeficiency virus (SIV) within Gag capsid (CA) protein and also SIV Vif protein, but displays a poor growth phenotype in simian cells. To improve the growth potential of NL-DT5R, we have constructed a series of its gag variant viruses. Out of fourteen viral clones generated, five were infectious for simian HSC-F cells, and two of the infectious variants grew similarly with NL-DT5R. Taking their genome structures into consideration, our data here clearly show that a narrow CA region within the Gag protein, i.e., the domain around cyclophilin A (CypA)-binding loop, is critical for the growth ability of HIV-1 in simian cells
Recognition of acrolein-specific epitopes by B cell receptors triggers an innate immune response
peer reviewedNatural antibodies, predominantly immunoglobulin M (IgM), play an important role in the defense against pathogens and in maintaining homeostasis against oxidized molecules known as oxidation-specific epitopes, such as those contained in oxidized low-density lipoproteins. However, owing to the complexity of the oxidized products, very few individual epitopes have been characterized in detail. In the present study, to identify endogenous sources of oxidation-specific epitopes, we stimulated mouse spleen and peritoneal cavity (PerC) cells in vitro with bovine serum albumin modified with a variety of lipid peroxidationârelated carbonyl compounds and identified the acrolein-modified bovine serum albumin as the most efficient trigger studied for the production of IgM in PerC cells. The acrolein-specific epitopes accelerated the differentiation of B-1a cells, a fetal-derived B cell lineage, to plasma cells. In addition, acrolein-modified bovine serum albumin was specifically bound to B-1a cells, suggesting the presence of an acrolein-specific IgMâB cell receptor (BCR). A hybridoma, RE-G25, producing an acrolein-specific IgM, was established from the PerC cells and was indeed identified as a population of B cells expressing a specific IgMâBCR. In addition, we analyzed the BCR repertoire of acrolein-specific B cells and identified the most frequent IgM heavy chain gene segments of the B cells. These data established the presence of innate B cells expressing the acrolein-specific BCR and suggested that in addition to our understanding of acrolein as a toxic aldehyde, it may play a role as a trigger of the innate immune response
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