554 research outputs found
An algebro-geometric proof of Witten's conjecture
We present a new proof of Witten's conjecture. The proof is based on the
analysis of the relationship between intersection indices on moduli spaces of
complex curves and Hurwitz numbers enumerating ramified coverings of the
2-sphere.Comment: 12 pages, no figure
Star Formation and Tidal Encounters with the Low Surface Brightness Galaxy UGC 12695 and Companions
We present VLA H I observations of the low surface brightness galaxy UGC
12695 and its two companions, UGC 12687 and a newly discovered dwarf galaxy
2333+1234. UGC 12695 shows solid body rotation but has a very lopsided
morphology of the H I disk, with the majority of the H I lying in the southern
arm of the galaxy. The H I column density distribution of this very blue, LSB
galaxy coincides in detail with its light distribution. Comparing the H I
column density of UGC 12695 with the empirical (but not well understood) value
of Sigma_c = 10E21 atoms/cm^2 found in, i.e., Skillman's 1986 paper shows the
star formation to be a local affair, occurring only in those regions where the
column density is above this star formation threshold. The low surface
brightness nature of this galaxy could thus be attributed to an insufficient
gas surface density, inhibiting star formation on a more global scale.
Significantly, though, the Toomre criterion places a much lower critical
density on the galaxy (+/-10E20 atoms/cm^2), which is shown by the galaxy's low
SFR to not be applicable.
Within a projected distance of 300kpc/30kms of UGC 12695 lie two companion
galaxies - UGC 12687, a high surface brightness barred spiral galaxy, and
2333+1234, a dwarf galaxy discovered during this investigation. The close
proximity of the three galaxies, combined with UGC 12695's extremely blue color
and regions of localized starburst and UGC 12687's UV excess bring to mind
mutually induced star formation through tidal activity.Comment: 14 pages, 8 figures (2 color), To be published in A.J., May 2000
Порівняльно-правовий аналіз інституту шлюбного договору за законодавством Німеччини та України
Казарян К. А. Порівняльно-правовий аналіз інституту шлюбного договору за законодавством Німеччини та України / К. А. Казарян // Правове життя сучасної України : матеріали Міжнар. наук. конф. проф.-викл. та аспірант. складу (м. Одеса, 16-17 травня 2013 р.) / відп. за вип. В. М. Дрьомін ; НУ "ОЮА". Півд. регіон. центр НАПрН України. - Одеса : Фенікс, 2013. - Т. 2. - С. 628-630
The combined use of imaging approaches to assess drug release from multicomponent solid dispersions
PURPOSE: Imaging methods were used as tools to provide an understanding of phenomena that occur during dissolution experiments, and ultimately to select the best ratio of two polymers in a matrix in terms of enhancement of the dissolution rate and prevention of crystallization during dissolution. METHODS: Magnetic resonance imaging, ATR-FTIR spectroscopic imaging and Raman mapping have been used to study the release mechanism of a poorly water soluble drug, aprepitant, from multicomponent amorphous solid dispersions. Solid dispersions were prepared based on the combination of two selected polymers - Soluplus, as a solubilizer, and PVP, as a dissolution enhancer. Formulations were prepared in a ratio of Soluplus:PVP 1:10, 1:5, 1:3, and 1:1, in order to obtain favorable properties of the polymer carrier. RESULTS: The crystallization of aprepitant during dissolution has occurred to a varying degree in the polymer ratios 1:10, 1:5, and 1:3, but the increasing presence of Soluplus in the formulation delayed the onset of crystallization. The Soluplus:PVP 1:1 solid dispersion proved to be the best matrix studied, combining the abilities of both polymers in a synergistic manner. CONCLUSIONS: Aprepitant dissolution rate has been significantly enhanced. This study highlights the benefits of combining imaging methods in order to understand the release process
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