Review seminar of educational progressivism, cultural encounters and reform in Japan (I) : record of speeches

This paper is a record of the review seminar on Educational Progressivism, Cultural Encounters and Reform in Japan (Oxon: Routledge, 2017), held on 15th October 2022 at Kobe University, Japan. It consists of an opening address, a transcript of speeches and a closing address. Throughout this paper, the transcript is subject to additions and deletions based on future research presentations. The seminar was made possible after we asked Dr Patrick Shorb and Dr Karsten Kenklies, the book reviewers, to deliver a lecture and they kindly agreed. We would like to thank them both sincerely. The record was emailed to all participants, including the two speakers, for confirmation before publication. It reflects requests for correction, but the final responsibility lies with Kawaji, the editor of the record. For some Japanese terminology, the editor has added English translations and explanations, whilst the original Japanese word is in square brackets ([]). We would like to thank Dr Shorn and Dr Kenklies for their presentations and would like to take this opportunity to thank all participants

Nuclear Pore Complex Protein Mediated Nuclear Localization of Dicer Protein in Human Cells

Human DICER1 protein cleaves double-stranded RNA into small sizes, a crucial step in production of single-stranded RNAs which are mediating factors of cytoplasmic RNA interference. Here, we clearly demonstrate that human DICER1 protein localizes not only to the cytoplasm but also to the nucleoplasm. We also find that human DICER1 protein associates with the NUP153 protein, one component of the nuclear pore complex. This association is detected predominantly in the cytoplasm but is also clearly distinguishable at the nuclear periphery. Additional characterization of the NUP153-DICER1 association suggests NUP153 plays a crucial role in the nuclear localization of the DICER1 protein