Clinical Experience With a New Type of Rhino-Larynx Electronic Endoscope PENTAX VNL-1530

We observed recordings of pictures obtained from patients with diseases of the larynx by using a new type of rhino-larynx electronic endoscope, PENTAXVNL-1530 connected to a video processor, PENTAX EPM-3300 (Asahi Optical Co., Ltd.). The electronic endoscope differs from the fiberoptic endoscope in that it contains a small light-sensitive charge coupled device (CCD) chip that is attached to the tip of the endoscope. This electronic endoscope has the smallest CCD camera of 5.1 mm in diameter, in the tip portion, and can be passed through the nasal passage into the laryngeal cavity. The dynamic image provided by this system is superior to that obtained by a flexible laryngofiberscope in resolution of the detail

Squamous Cell Carcinoma With Sarcomatous Stroma of the Mesopharynx

A case of squamous cell carcinoma with sarcomatous stroma of the mesopharynx is presented. The patient was a 62-year-old man who complained of a foreign body sensation. Endoscopic examination revealed a large pedunculated mass arising from the posterior wall of the mesopharynx. The lesion was surgically resected, using a cutting snare by the endo-oral approach, and was completely removed. A diagnosis of squamous cell carcinoma with sarcomatous stroma was made histopathologically. The clinicopathological features of this case are described and compared with those of previously reported cases

Electronic Videoendoscopy of Laryngeal Lesions Using a New Type of Rhinolarynx Endoscope Portion

Patients with laryngeal lesions were observed and the lesions were recorded with an electronic videoendoscope system using the PENTAX EPM-3300 video processor and the PENTAX VNL-1330 endoscope portion. The electronic videoendoscope system differs from the conventional fiberoptic endoscope connected to a video camera in that a small monochrome charge-coupled device (CCD) chip is built in the tip of the endoscope portion. The PENTAX VNL-1330 rhinolarynx endoscope portion has a tip and insertion tube of approximately 4mm in outer diameter to allow its introduction through the nasal passages into the larynx. The dynamic color images provided by this system were superior to those obtained by a conventional rhinolarynx flexible fiberscope connected to a video camera in both quality and resolution of detail. This system should be useful in diagnosing laryngeal lesions

Verrucous Carcinoma of the Larynx Presenting as a Hairy Whitish Tumor

A patient was encountered with verrucous carcinoma of the larynx that presented as a hairy whitish tumor. There was a recurrence because simple excision with forceps by endolaryngeal microsurgery was performed in the first operation. However, in the second operation endolaryngeal microscopic laser surgery using a direct laryngoscope was performed and followed by adjuvant chemotherapy with oral UFT, a combination of uracil and tegafur in a molar ratio of 4:1. The patient’s course has been favorable to date. The case is reported in this paper and discussed from the viewpoint of diagnosis and treatment of this neoplasm

Lymphoepithelial Cyst of the Hypopharynx

A rare case of lymphoepithelial cyst formed in the piriform sinus of the hypopharynx is reported. Histopathological examination revealed a lymphoepithelial cyst. It was removed by laryngomicrosurgical technique using a side-opened direct laryngoscope. Because this cyst was wide-based on the antero-medial region in the right piriform sinus of the hypopharynx, the mucous membrane around the cyst was incised electrosurgically and then detached to facilitate removal. In this paper, we describe our surgical procedure for removing the cyst in this case and discuss the possible causes of the disease

Initial Experience of Endoscopic Phonosurgery With a Prototype of the Therapeutic Rhinolarynx Electronic Endoscope

We performed endoscopic phonosurgery in a patient with a laryngeal lesion using a prototype of the therapeutic rhino-larynx electronic endoscope connected to a video processor (Asahi Optical Co., Ltd.). This therapeutic electronic endoscope differs from the fiberoptic endoscope, because it contains an instrument channel and a miniature television camera attached to the tip of the endoscope, consisting of a small light-sensitive CCD chip. The dynamic image provided by this system is superior in resolution to that obtained by conventional flexible laryngofiberscopes. Using this therapeutic electronic endoscope and flexible forceps, we succeeded in removing a vocal fold polyp. This endoscope can be passed through the nasal passage into the laryngeal cavity. The therapeutic electronic endoscope is introduced and a clinical case is presented

Conservative Therapy for Nonspecific Granuloma of the Larynx Using a Beclomethasone Dipropionate Inhaler

Nonspecific granuloma of the larynx is a benign tumor that usually occurs on the posterior glottis. Conventional treatment for this laryngeal lesion has consisted of surgical resection. However, this lesion has a strong tendency to recur postoperatively and may require multiple repeated operative procedures. Conservative treatment, consisting mainly of beclomethasone dipropionate inhalation therapy, was instituted in 20 cases with good results. We discussed the effect of beclomethasone dipropionate on this lesion as well as the etiology of this disease

Newly Designed Specula for Laryngomicroscopy

We produced specula for laryngomicroscopy to observe blind spots in the operating field. Use of these specula has facilitated detailed observation of the lower surface of the false vocal folds, laryngeal ventricle, and subglottis, which were previously in blind spots. The specula are useful in the following ways: 1) clarifying blind spots for improved diagnosis and providing more accurate surgical margins; 2) observing the lower lips of the vocal folds in phonosurgery; and 3) Vaporizing with laser reflection. The specula are cheap and easy to use and are well worth considering for application to laryngomicroscopy

マングローブ域におけるカニ類の分布とセルロース分解能との関係

学位の種別: 課程博士審査委員会委員 : （主査）東京大学教授 佐野 光彦, 東京大学教授 河村 知彦, 東京大学准教授 岡本 研, 東京大学准教授 山川 卓, 三重大学大学院生物資源学研究科准教授 木村 妙子University of Tokyo(東京大学

Low-grade osteosarcoma is predominant in gnathic osteosarcomas: A report of seven cases of osteosarcoma of the jaw

OBJECTIVE: Primary osteosarcoma of the jaw bones is very rare, and histological features of gnathic osteosarcoma remain obscure. The purpose of this study was to describe the clinicopathological features of gnathic osteosarcoma. MATERIALS AND METHODS: Seven cases of gnathic osteosarcoma from Japan diagnosed during the period between 2000 and 2016 were examined retrospectively. The histology of the surgical pathology materials was reviewed by two pathologists. Clinical information was obtained from the hospital's information system. RESULTS: Of the seven cases, two patients had secondary osteosarcomas. As for the five cases of primary osteosarcoma, their ages ranged from 26 to 58 years (mean: 36.2, median: 28). Histologically, three cases were fibrotic tumors composed of spindle‐shaped cells with mild to moderate nuclear atypia and the collagenous stroma accompanied by woven bones or mature lamellar‐like bones. Two cases had cartilage formation. MDM2 and CDK4 expression was observed in two out of three cases on immunostaining. The histopathology of these three cases was regarded as the counterpart of low‐grade osteosarcomas, namely, parosteal osteosarcoma and low‐grade central osteosarcoma, arising in long bones. CONCLUSIONS: The surprisingly high incidence (60%, 3/5 cases) of low‐grade osteosarcoma explains the reason why gnathic osteosarcomas present a more favorable prognosis than osteosarcomas arising in long bones. Furthermore, it provides insight into the tumorigenesis mechanism of low‐grade osteosarcomas arising in the jaw and other sites