34 research outputs found
An approach towards iris localization for non cooperative images: A study
Iris localization is the most important part of iris recognition which involves the detection of iris boundaries in an image. A very important need of this effective security system is to overcome the rigid constraints necessitated by the practical implementation of such a system. There are a few existing techniques for iris segmentation in which iris detection using Circular Hough Transform is the most reliable and popular and it has been implemented in this project. But there is a shortcoming in this technique. It does not perform well and does not gives high accuracy with images containing noise or occlusions caused by eyelids. Such kind of images constitute non cooperative data for iris recognition. To provide acceptable measures of accuracy, it is critical for an iris recognition system to overcome various noise effects introduced in images captured under different environment such as occlusions due to eyelids. This report discusses an approach towards less constraint iris recognition using occluded images. The Circular Hough Transform is implemented for few images and a novel approach towards iris localization and eyelids detection is studied.
A Hybrid Filter for Image Enhancement
Image filtering processes are applied on images to remove the different types of noise that are either present in the image during capturing or introduced into the image during transmission. The salt & pepper (impulse) noise is the one type of noise which is occurred during transmission of the images or due to bit errors or dead pixels in the image contents. The images are blurred due to object movement or camera displacement when we capture the image. This pepper deals with removing the impulse noise and blurredness simultaneously from the images. The hybrid filter is a combination of wiener filter and median filter
Thermo-electric generation (TEG) enabled cookstoves in a rural Indian community: a longitudinal study of user behaviours and perceptions
Background: Traditional cookstoves that burn solid biomass are associated with inefficient burning, a high degree of household air pollution and high morbidity rates. A key barrier to the adoption of clean cookstoves has been the cost of fuels. Hence, a Thermo-Electric Generating (TEG) cookstove that used solid biomass fuels more efficiently and released less smoke was developed. The TEG cookstove also generates electricity to power small electric devices. Fifteen TEG cookstoves were distributed to villagers in the Indian state of Uttarakhand in 2019. / Objective: We wanted to understand whether, after two years of distribution, TEG cookstoves were still used, what and where they were used for, their perceived impacts on health, and the barriers to their use. / Methods used: We surveyed 10 of the 15 recipient households. We applied the Capability, Opportunity, Motivation-Behaviour and Behaviour Change Wheel frameworks to understand what the barriers to adoption were, and what could be done to surmount these. / Results: All respondents reported lower smoke levels and most respondents reported that the TEG cookstoves required less fuelwood than their traditional cookstoves, but none had used them in the month prior to the survey. / Discussion: For those whose TEG cookstoves were still usable and had not been made redundant by clean cookstoves, we found there to be physical opportunity barriers and psychological capability barriers. Physical opportunity barriers included a small inlet for fuel, limited versatility beyond cooking at low temperatures, and the availability of only one hob. To surmount these barriers, we recommend co-design to suit user needs and education emphasising visible benefits of avoided soot on kitchen walls, in addition to the health benefits
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
Background
Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear.
Methods
RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047.
Findings
Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61–69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1–10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688–1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4–82·5) in the no ADT group and 80·4% (76·6–83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths.
Interpretation
Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population
Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial
Background
Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain.
Methods
RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and
ClinicalTrials.gov
,
NCT00541047
.
Findings
Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60–69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0–10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612–0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6–75·7) in the short-course ADT group and 78·1% (74·2–81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths.
Interpretation
Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy.
Funding
Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society
Field Based Assessment of <i>Capsicum annuum</i> Performance with Inoculation of Rhizobacterial Consortia
Plant growth promoting rhizobacteria (PGPR) are associated with plant roots and augment plant productivity and immunity by reducing fertilizer application rates and nutrient runoff. Studies were conducted to evaluate bell pepper transplants amended with formulation of consortium of two indigenous PGPR isolates (Bacillus subtilis and Bacillus pumilus) in terms of increase in yield and disease resistance under field conditions. Transplants were planted into plots treated by NPK (nitrogen, phosphorus and potassium), fungicides, soil solarization, MeBr fumigation, PGPR and untreated soil. Treatments were assessed for incidence of soil-borne phytopathogens viz. Phytophthora capsici and Colletotrichum sp. Highly significant increases in bell pepper transplant growth occurred in response to formulations of PGPR isolates. Transplant vigor and survival in the field were also improved by PGPR treatments. Consortium of Bacillus subtilis and Bacillus pumilus reduced disease incidence of damping off by 1.81% and anthracnose by 1.75%. Numbers of colony forming units of Phytophthora capsici and Colletotrichum sp. were significantly higher in all plots than those treated with PGPR consortium. Incidence of seed rot and seedling blight on bell pepper was significantly lower in PGPR-treated plots and highest in untreated plots. Total fruit yield of bell pepper increased by 379.36% with PGPR consortium (Bacillus subtilis and Bacillus pumilus)
A RARE CASE REPORT ON TUBULAR APOCRINE ADENOMA
A RARE CASE REPORT ON TUBULAR APOCRINE ADENOMA
Tubular apocrine adenoma, the apocrine variant of papillary tubulopapillary hidradenoma is a rare well-circumscribed, intradermal benign tumor, with tubular structures showing apocrine differentiation. It usually presents as a slow growing well-circumscribed nodule. The most common site of involvement is the scalp. Although it has also been reported to occur at other sites like face, neck, axilla, trunk, upper and lower extremities. The present study describes a case of 76 years old female who presented with swelling on back. An excisional biopsy was performed which on histopathological examination show multiple irregular shaped tubular structures lined by two layers of epithelial cells focally. On histopathology case was diagnosed as Tubular Apocrine Adenoma.
Keywords : Hiradenoma, Tubualar Apocrine adenoma, syringocystadenoma papilliferum.