32 research outputs found
The synergistic action of caffeine or adenosine on glucose stimulation of liver glycogen synthase phosphatase activity
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Site-site interactions in glycogen phosphorylase b probed by ligands specific for each site
No full textStructural changes in glycogen phosphorylase induced by phosphorylation.
No full textA comparison of the refined crystal structures of dimeric glycogen phosphorylase b and a reveals structural changes that represent the first step in the activation of the enzyme. On phosphorylation of serine-14, the N-terminus of each subunit assumes an ordered helical conformation and binds to the surface of the dimer. The consequent structural changes at the N- and C-terminal regions lead to strengthened interactions between subunits and alter the binding sites for allosteric effectors and substrates
Defective Glycogenesis Contributes Toward the Inability to Suppress Hepatic Glucose Production in Response to Hyperglycemia and Hyperinsulinemia in Zucker Diabetic Fatty Rats
No full textRabbit muscle phosphorylase derivatives with oligosaccharides covalently bound to the glycogen storage site
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