2 research outputs found
The value of the Duke Activity Status Index (DASI) in predicting ischaemia in myocardial perfusion scintigraphy — a prospective study
BACKGROUND: Functional capacity assessment may be
a useful tool to stratify patients according to risk of coronary
artery disease (CAD). The Duke Activity Status Index (DASI)
is a functional assessment based on activities of daily living
and cardiovascular fitness, assessed using a self-administered
questionnaire.
MATERIAL AND METHODS: We assessed the relationship
between established clinical risk factors for CAD and the DASI
with results of myocardial perfusion scintigraphy (MPS). The
MPS results used in the analysis were the presence of reversible
ischaemia and the resting left ventricular ejection fraction (LVEF).
A DASI self-administered questionnaire was completed by 117
consecutive participants, and a patient history was taken to
ascertain established risk factors. All participants underwent
a stress test, and myocardial perfusion scintigraphy was performed. Statistical analysis consisted of logistic and linear
regression using a statistical software package.
RESULTS: The DASI was the only factor that correlated significantly
with reversible ischaemia on MPS. None of the previously
established risk factors had a significant association with reversible
ischaemia within the model. Our study found a potential
relationship between the DASI score and the left ventricular ejection
fraction (LVEF) although this was not statistically significant.
CONCLUSIONS: Our study findings suggest that the DASI may
represent a powerful tool for risk stratification prior to investigation
of CAD. A further study with a larger sample size will be
required to investigate the predictive value of the DASI and the
association with LVEF.
Nuclear Med Rev 2010; 13, 2: 59–6