Link Before You Share: Managing Privacy Policies through Blockchain

With the advent of numerous online content providers, utilities and applications, each with their own specific version of privacy policies and its associated overhead, it is becoming increasingly difficult for concerned users to manage and track the confidential information that they share with the providers. Users consent to providers to gather and share their Personally Identifiable Information (PII). We have developed a novel framework to automatically track details about how a users' PII data is stored, used and shared by the provider. We have integrated our Data Privacy ontology with the properties of blockchain, to develop an automated access control and audit mechanism that enforces users' data privacy policies when sharing their data across third parties. We have also validated this framework by implementing a working system LinkShare. In this paper, we describe our framework on detail along with the LinkShare system. Our approach can be adopted by Big Data users to automatically apply their privacy policy on data operations and track the flow of that data across various stakeholders.Comment: 10 pages, 6 figures, Published in: 4th International Workshop on Privacy and Security of Big Data (PSBD 2017) in conjunction with 2017 IEEE International Conference on Big Data (IEEE BigData 2017) December 14, 2017, Boston, MA, US

Participation of Self Help Group Tribal Women in Economic and Social Developmental Activities

A study was taken up among the tribal women in the Nilgiris district mainly to assess the extent of participation of tribal women SHG members in various developmental activities.Kotagiri and Gudalur blocks were selected based on the presence of NGOs specifically working for the tribes. Totally eight SHGs have been randomly selected for the study. This comprises four each from Todas and Kattunayakas. A sample of 10 members from each SHGs have been randomly selected. Thus the total sample size is 80. The results indicated that the overall analysis indicate that majority (55.00%) of the tribal women hadmedium level of participation followed by high and low levels

Computerized Protein Modeling and Molecular Docking Analysis of Human Proto Oncogene Tyrosine Protein Kinase YES for Discovery of Novel Lead Molecules

Human proto-oncogene tyrosine-protein kinase YES (YES) is a non receptor kinase belongs to Src family. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. In hepatocellular carcinoma and colorectal carcinoma elevated human YES activity was observed. Inhibitors of human YES reported till date are in clinical trials and associated with several side effects. The present study was mainly aimed in homology modeling of human YES and discovery of novel lead molecules that inhibit YES kinase more efficiently with fewer side effects. Virtual screening and docking techniques were applied to identify novel lead molecule of YES kinase. As there was no reported human YES crystal structural data, the three dimensional structure of human YES was constructed based on template structure (PDB ID: 2H8H) obtained through homology search using MODELLER 9V7. The model was refined, energy minimized and assessed through PROCHECK. Active site residues of human YES were identified from the homology model in complex with template ligand AZD0530 and were further confirmed using CASTp. Five published inhibitors of YES family (Dasatinib, Bosutinib, SU6656, AZD0530 and CGP77675) were identified through literature search. High throughput virtual screening method at Ligand.Info was applied for these five inhibitors to establish a library of 1932 structural analogs. LigPrep was used to generate possible conformations of each ligand molecules from structural analog library. The ligand duplicates conformers, ligands having reactive functional group and poor ADME properties were rejected from the prepared dataset. Glide 5.5 was used to generate a grid box by picking the active site residues of human YES protein. Through sequential applications of stringent mode glide docking procedures from Glide HTVS to SP to XP respectively, 13 potential inhibitors were proposed. The docking complexes of each inhibitor with human YES protein were analyzed and lead ‘1’ molecule was identified to have higher binding affinity to human YES protein (XP Gscore: -12.07 Kcal/mol) compared to existing published inhibitors and other 12 lead molecules. The lead ‘1’ - human YES docking complex was highly stabilized through hydrogen bond network with amino acid residues Thr348, Asp358, Asp414 and Phe415. Moreover, from the results obtained we could decipher that lead ‘1’ molecule can be raised into potential inhibitors after binding assays, substantiated experimental investigations and passing several phases of clinical trials

Kevin Marsh: ethical journalism (Polis summer school – guest blog)

This guest blog was written by Polis Summer School student Karuna Kumar At a time when the News of the World’s unscrupulous journalistic ethics are hitting the headlines across the globe it is difficult to stand on the other side of the table and reinstate faith in the moral ideologies of British Journalism. One man, ventured out to do just that and with much confidence and pride. Kevin Marsh, Editor of the BBC College of journalism stood before a class of around 40 students at the LSE Summer School and shared his experiences at the BBC – an organisation that stands as an inspiration for journalists around the world for the ethics and qualitative reporting it supports

Smart Atm Cardholders’ Attitude And Usage Level - A Study Of Sungai Petani Residents

Smart card technology has experienced tremendous growth on the global basis in the application of various sectors such as transportation, health, telecommunication, insurance, financial industry and etc. It has changed the way the world doing business and consumer make purchasers on a daily basis. Smart card has been designed to become the future method of payment and information storage system. It has been utilized excessively during the last couple of decades. It provides better security, intelligence, speed and convenience

Structural modelling of suspension bridges with particular reference to the humber bridge

This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The purpose of this research was to investigate the parameters that influence the structural behaviour of a specific suspension bridge, The Humber Bridge. Three finite element computer models of increasing complexity were created for the analyses. They were validated against field measurements for both static and dynamic loading, and good correlation was obtained. The programs were used to a) Assess the integrity of the bridge as a whole were three failures of certain individual elements, such as a hanger falling under vehicle impact; b) Determine the influence of the sizing of individual components, such as deck plate thickness or main cable diameter, on overall behaviour; c) ascertain the capability of the structure to cope with loading (traffic, wind orthermal), above the original design values; and d) consider the performance of the bridge had other configurations of hangers been adopted in the original design. From the results of this work, recommendations are made which could influence the future design of long-span suspension bridges

AN INVESTIGATION OF THE POSSIBILITIES OF ROOM-SCALE WIRELESS POWER TRANSFER

Inspired by original work of Nikola Tesla in resonant inductive coupling, numerous investigations are going on making wireless power transfer (WPT) application an optimum choice for various fields. By implementing the concept of non-radiative magnetically-coupled resonant circuits, it has been found that wireless power transmission is achievable at room-scale. This thesis investigates various aspects of the possibilities of room-scale wireless power transfer. Firstly, following the background of WPT systems, MATLAB-coil design, calculation of mutual inductances and Excel-calculation of WPT system performance in multi-resonator systems design tools for WPT systems are discussed for estimating the performance of numerous WPT resonator networks at room-scale. Secondly, the WPT system with two transmitters and a load receiver was simulated for measuring resonator parameters and flux-coupling coefficients between inductors using MATLAB and excel computational tools. Also, the WPT network of four-transmitter coil system was proposed to overcome the shortcomings of two-transmitter coil system xiii incapable of transmitting power efficiently at the various orientation of receiver coil. The goal of this design was to permit greater flexibility in angular position, or attitude of the receiver coil at the room space. The simulated results were found to be promising for room-scale wireless power transmission. The chapter concludes with a design validation that is efficient for a room-scale wireless power transmission. Conclusions and suggestions for future work are provided