Synthesis and antimicrobial activity of coumarin derivatives metal complexes: An in vitro evaluation

Complexes of 3-[ {-(3&rsquo;,4&rsquo;-di methoxy phenyl) }-prop-2-enoyl]-4-hydroxy-6-methyl-2H-chromene-2-one with Cu(II), Ni(II), Fe(II), Co(II) and Mn(II) have been synthesized and characterized using elemental analysis, IR spectra and conductivity measurements. These studies revealed that they are having octahedral geometry of the type [ML2(H2O)2]. In vitro antimicrobial activity of all synthesized compounds and standard drugs have been evaluated against four strains of bacterial culture and one fungus, which includes two gram +ve bacterial culture and two gram -ve bacterial culture. The compounds show net enhancement in activity on coordination of metals with ligand but moderate activity as compared to standard drugs.</div

Ethyl 2-(3,5-dimethyl-1,1-dioxo-2H-1&amp;#955;6,2,6-thiadiazin-4-yl)benzoate

In the title compound, C14H16N2O4S, the thiadiazine ring is in a half-boat conformation. The aromatic ring deviates from the plane of this moiety at an angle of 74.6&amp;#8197;(2)&amp;#176;. The structure displays intermolecular N&amp;#8212;H...O hydrogen bonding [N...O = 2.8157&amp;#8197;(16)&amp;#8197;&amp;#197;], creating ribbons along the [010] axis. There are also weak C&amp;#8212;H...O interactions in the crystal but no &amp;#960;&amp;#8211;&amp;#960; stacking

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present