1,339 research outputs found

    The civic turn of immigrant integration policies in the Scandinavian welfare states

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    This special issue addresses the question of how to understand the civic turn within immigrant integration in the West towards programs and instruments, public discourses and political intentions, which aim to condition, incentivize, and shape through socialization immigrants into ‘citizens’. Empirically, it focuses on the less studied Scandinavian cases of Sweden, Norway, and Denmark. In this introduction, we situate the contributions to this special issue within the overall debate on civic integration and convergence. We introduce the three cases, critically discuss the (liberal) convergence thesis and its descriptive and explanatory claims, and explain why studying the Scandinavian welfare states can further our understanding of the nature of the civic turn and its driving forces. Before concluding, we discuss whether civic integration policies actually work

    Dynamic composition, shaping and organization of plastid nucleoids

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    In this article recent progress on the elucidation of the dynamic composition and structure of plastid nucleoids is reviewed from a structural perspective. Plastid nucleoids are compact structures of multiple copies of different forms of ptDNA, RNA, enzymes for replication and gene expression as well as DNA binding proteins. Although early electron microscopy suggested that plastid DNA is almost free of proteins, it is now well established that the DNA in nucleoids similarly as in the nuclear chromatin is associated with basic proteins playing key roles in organization of the DNA architecture and in regulation of DNA associated enzymatic activities involved in transcription, replication, and recombination. This group of DNA binding proteins has been named plastid nucleoid associated proteins (ptNAPs). Plastid nucleoids are unique with respect to their variable number, genome copy content and dynamic distribution within different types of plastids. The mechanisms underlying the shaping and reorganization of plastid nucleoids during chloroplast development and in response to environmental conditions involve posttranslational modifications of ptNAPs, similarly to those changes known for histones in the eukaryotic chromatin, as well as changes in the repertoire of ptNAPs, as known for nucleoids of bacteria. Attachment of plastid nucleoids to membranes is proposed to be important not only for regulation of DNA availability for replication and transcription, but also for the coordination of photosynthesis and plastid gene expression

    Telemedical Maritime Assistance Service (TMAS) to Swedish merchant and passengers ships 1997–2012

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    Background: Telemedical Maritime Assistance Service (TMAS) for seafarers and traveling passengers is important and can be crucial for the optimal medical treatment on board ships. The aim of this study was to analyse and to compare the data from consultations and evacuations from merchant ships and passenger ferries for possible improvements. Materials and methods: Data for seafarers from 1997, 2002 and 2007 and for passengers on Swedish ferries for the years 2007, 2009, 2011 and 2012 from the Swedish Radio Medical were studied. Symptoms and diseases were classified according to the International Classification for Primary Care (ICPC-2). The distribution of symptoms, accidents and diseases, treatments/actions taken, evacuations and the communication forms were analysed. Results: One thousand ninety-five contacts for seafarers from merchant ships and 651 passenger patients from Swedish ferries were analysed. While the evacuations for the seafarers gradually decreased over the years from 18% in 1997 to 14% in 2007, still 39.5% of the passenger patient contacts were evacuated mainly by helicopters and 70 patients were picked up by an ambulance on the quay. Accidents were 20% for seafarers and 25% for passengers of the contacts. Evacuations for passengers were mainly in the diagnostic groups: unspecific (A), digestive (D), cardiology (K), musculoskeletal (L) and neurology (N). The use of VHF, radio communications and fax machines have been greatly reduced while the use of e-mail and satellite phone increased. Conclusions: No significant differences in reasons for contact or actions over the years have been identified. The evacuations of seafarers decreased over the years but was stable among the passenger patients (39%). The circumstances and reasons behind the evacuations should be analysed for prevention. Standard forms and digital images for documentation can facilitate knowledge exchange and further studies.

    Brain mechanisms in pain regulation

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    The subjective sensitivity to pain differs greatly between individuals and neuroimaging has contributed to the understanding of the cerebral mechanisms involved in pain regulation. The descending pain inhibitory circuitry is a well defined cerebral network that enables regulation of afferent nociceptive information. The aim of this thesis was to investigate different aspects of pain modulation in patients with Fibromyalgia (FM) as well as the impact of specific genetic variations on pain sensitivity dynamics in healthy subjects. Study I demonstrated that patients with FM had an impaired mechanism for descending pain inhibition and that this deficiency was paired with a diminished activation of the rostral anterior cingulate cortex and the brainstem, two regions that play an important role in descending pain regulation. These results advance the understanding of the pathophysiology in FM and provide new directions for the development of effective treatments. Study II investigated the possible impact of negative mood on pain processing in patients with FM and found that brain activity during experimental pain was not modulated by depressive symptoms, anxiety, or catastrophizing thoughts. The activity of the brain regions previously implicated in the pathophysiology of FM were not correlated with high ratings of negative mood which suggests that there are two segregated cerebral mechanisms dealing with pain and negative mood in FM. In study III patients with FM were treated with a Noradrenaline-Serotonin Reuptake Inhibitor (milnacipran) or placebo for 12 weeks. All patients that reported an improvement of symptoms after treatment, including both milnacipran and placebo responders, were compared and results revealed that sensitivity to pressure improved selectively in milnacipran responders. This decreased sensitivity also correlated to the improvement of ongoing clinical pain. The study suggests that the specific effect of milnacipran acts through direct antinociceptive effects and/or by the strengthening of the endogenous pain inhibitory mechanisms. In study IV the genetic influence on the descending pain inhibitory function in healthy subjects was assessed. Results demonstrate that a genetic polymorphism (COMTval158met) with influence on the function of the noradrenergic and dopaminergic systems, is related to the response dynamics of repeated pain stimulations following opioid administration. Results suggest that the initial pain response is not influenced by the COMTval158met polymorphism but when the system is challenged the difference is expressed

    Experiences of Social Isolation in Older Hospitalized Patients with COVID-19 and Their Close Relatives: A Qualitative Study

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    Background: Proximity between older patients and their close relatives is essential during hospitalisation. During the first wave of the pandemic, the Danish Patient Safety Authority restricted no hospital visitors. Aim: To explore how older patients with COVID-19 and their close relatives experienced physical separation during hospitalization. Method: A qualitative study using semi-structured interviews and thematic analysis was employed. Findings: Six interviews were conducted: three patients with a mean age of 81 years and three close relatives—two daughters and one spouse. The patients felt boredom, loneliness, and a sense of imprisonment, yet they felt safe and satisfied. Isolation was known beforehand from the media. Close relatives emphasised that information, involvement, and collaboration with hospital staff were crucial. Conclusion: Although older patients with COVID-19 and their close relatives widely accept their situation during hospitalization, they experience negative consequences from social isolation

    Bilinear forms on Grothendieck groups of triangulated categories

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    We extend the theory of bilinear forms on the Green ring of a finite group developed by Benson and Parker to the context of the Grothendieck group of a triangulated category with Auslander-Reiten triangles, taking only relations given by direct sum decompositions. We examine the non-degeneracy of the bilinear form given by dimensions of homomorphisms, and show that the form may be modified to give a Hermitian form for which the standard basis given by indecomposable objects has a dual basis given by Auslander-Reiten triangles. An application is given to the homotopy category of perfect complexes over a symmetric algebra, with a consequence analogous to a result of Erdmann and Kerner.Comment: arXiv admin note: substantial text overlap with arXiv:1301.470

    Controlling stormwater quality with filter soil-event and dry weather testing

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    The use of filter soil is increasing for control of quality of stormwater runoff prior to infiltration or discharge. This study aimed to gain knowledge about treatment efficacy of filter soils at field scale. Percolate samples from swale-trench systems with filter soil based on agricultural till with/without limestone were monitored for 15 and 9 rain events respectively. Further, two curb extensions with filter soil based on landfill soil were monitored for 10 and 8 events. Pollutant concentrations in percolate were compared to influent samples from the catchment area. Additionally one of the curb extensions was tested twice by adding high-dose synthetic influent containing runoff pollutants of concern. Despite generally low influent pollutant levels, phosphorus, copper, zinc, lead and some polyaromatic hydrocarbons exceeded guiding criteria for protection of groundwater and freshwater. Concentrations in the percolate were in most cases reduced, but phosphorus increased and despite reduced concentrations copper, lead and benzo(a)pyrene still exceeded guiding criteria. Pollutants from the synthetic influent were efficiently retained, except the pesticide MCPA. Filter soil based on landfill soil tended to perform better than agricultural till. No impact of limestone was observed. Overall the filter soils performed well in retaining pollutants, despite simultaneous processes of mobilization and immobilization
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