32 research outputs found

    Logarithmic Correction to BMSFT Entanglement Entropy

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    Using Rindler method we derive the logarithmic correction to the entanglement entropy of a two dimensional BMS-invariant field theory (BMSFT). In particular, we present a general formula for extraction of the logarithmic corrections to both the thermal and the entanglement entropies. We also present a CFT formula related to the logarithmic correction of the BTZ inner horizon entropy which results in our formula after taking appropriate limit.Comment: 15 pages, V2: Minor corrections, V3: Published versio

    An Artificial Neural Network for Movement Pattern Analysis to Estimate Blood Alcohol Content Level

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    Impairments in gait occur after alcohol consumption, and, if detected in real-time, could guide the delivery of “just-in-time” injury prevention interventions. We aimed to identify the salient features of gait that could be used for estimating blood alcohol content (BAC) level in a typical drinking environment. We recruited 10 young adults with a history of heavy drinking to test our research app. During four consecutive Fridays and Saturdays, every hour from 8 p.m. to 12 a.m., they were prompted to use the app to report alcohol consumption and complete a 5-step straight-line walking task, during which 3-axis acceleration and angular velocity data was sampled at a frequency of 100 Hz. BAC for each subject was calculated. From sensor signals, 24 features were calculated using a sliding window technique, including energy, mean, and standard deviation. Using an artificial neural network (ANN), we performed regression analysis to define a model determining association between gait features and BACs. Part (70%) of the data was then used as a training dataset, and the results tested and validated using the rest of the samples. We evaluated different training algorithms for the neural network and the result showed that a Bayesian regularization neural network (BRNN) was the most efficient and accurate. Analyses support the use of the tandem gait task paired with our approach to reliably estimate BAC based on gait features. Results from this work could be useful in designing effective prevention interventions to reduce risky behaviors during periods of alcohol consumption

    MicroRNA and Cancer Treatment: A Commentary

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    MiRNAs play an important role as oncogenes and tumor suppressors in induction and suppression of tumor effects. Also in different stages of cancer therapy. High and low expression of some miRNAs could be used as factors for prognosis patients drug resistant. Regulation of these miRNA perform by some other miRNA that can suppression or active the translation of downstream miRNA, Therefore, miRNAs play important role in the individual treatments and classification of miRNA in diagnosis and prognosis is highly valuable, also we could consider miRNA as a setting key for switching and off of genes

    A robust optimization approach for the production-routing problem with lateral transshipment and outsourcing

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    Despite the fact that there is a large body of literature on the Production Routing Problem (PRP), we were struck by the dearth of research on outsource planning and lateral transshipment. This paper presents a mixed-integer linear programming model for incorporating outsourcing, lateral transshipment, back ordering, lost sales, and time windows into production routing problems. Then a robust optimization model will be introduced to overcome the detrimental effects of demand uncertainty. Considering the scale and complexity of the suggested problem, addressing it in a reasonable time was a challenge. Therefore, three matheuristic algorithms, including Genetic Algorithm (GA), Simulated Annealing (SA), and Modified Simulated Annealing (MSA), are developed for solving large-scale problems. Eventually, computational experiments on disparate instances are performed, and the results show the effectiveness and efficiency of the proposed algorithms. In other words, our recommended algorithms outperform the CPLEX solver in terms of the quality and time of obtaining the solutions
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