2 research outputs found
Candida spp. other than Candida albicans : A major cause of fungaemia in a tertiary care centre
This study was conducted to determine the frequency of different
Candida spp. isolated from different parts of the hospital,
associated risk factors and mortality rate. A total of 59 cases were
selected for prospective analysis over a period of one and half years.
Blood samples collected were processed by BACTEC (9240) method.
Candidaemia was diagnosed by positive blood culture at least from two
blood culture samples or from a clinically significant single blood
culture sample. Candida spp. were identified by standard techniques.
Most frequent isolates were C. tropicalis (35.6%), C. parapsilosis
(28.8%), C. glabrata (11.9%) and C. pelliculosa (11.9%). Candida
albicans was isolated only in 3.4% cases. Neonatology department
accounted for highest number of isolates (27.1%), followed by
gastrointestinal surgery (15.3%) and cardiac surgery (13.6%). Mortality
was noted in 16.9%. Probable risk factors determined were intensive
care unit stay (74.6%), antibiotic therapy (50.8%), central line
(42.4%), urinary catheter (32.2%), ventilator (23.7%), malignancy
(20.3%) and abdominal surgery (15.3%)
Chronic subdural empyema and cranial vault osteomyelitis due to Salmonella paratyphi A
Intracranial infections, especially subdural empyema, due to salmonella
are rare. Subdural empyema caused by Salmonella paratyphi A has been
documented only once earlier in the literature. Hence, we report a case
of subdural empyema and osteomyelitis of cranial vault due to S.
paratyphi A. A 42- year-old male presented with headache and purulent
discharge from right parietal burr hole wound site. Patient gave a
history of head injury two years ago. He underwent burr hole evacuation
of chronic subdural haematoma, excision of outer membrane and right
parietal craniectomy. The cultures grew S. paratyphi A. Recovery was
uneventful following surgical intervention and antibiotic therapy