Cross-component prediction in HEVC

Video coding in the YCbCr color space has been widely used, since it is efficient for compression, but it can result in color distortion due to conversion error. Meanwhile, coding in RGB color space maintains high color fidelity, having the drawback of a substantial bit-rate increase with respect to YCbCr coding. Cross-component prediction (CCP) efficiently compresses video content by decorrelating color components while keeping high color fidelity. In this scheme, the chroma residual signal is predicted from the luma residual signal inside the coding loop. This paper gives a description of the CCP scheme from several point-of-view, from theoretical background to practical implementation. The proposed CCP scheme has been evaluated in standardization communities and adopted into H.265/HEVC Range Extensions. Experimental results show significant coding performance improvements both for natural and screen content video, while the quality of all color components is maintained. The average coding gains for natural video are 17% and 5% bit-rate reduction in case of intra coding, and 11% and 4% in case of inter coding for RGB and YCbCr coding, respectively, while the average increment of encoding and decoding times in the HEVC reference software implementation are 10% and 4%, respectively

Curcumin inhibits proliferation of human lens epithelial cells: a proteomic analysis*

Objective: The incidence of after-cataracts [also known as posterior capsular opacification (PCO)] is between 30% and 50% three years following cataract surgery. Suppressing the proliferation of lens epithelial cells (LECs) is a primary goal in preventing PCO. Here, we investigated the proteomic regulation of the inhibitory effects of curcumin (Cur) on the proliferation of human lens epithelial B3 (HLE-B3) cells. Methods: Recombinant human basic fibroblast growth factor (rhbFGF) was used to induce proliferation of HLE-B3 cells, which were incubated with 20 mg/L Cur in a CO2 incubator for 24 h. Results: We found that the absorbance (A) value of rhbFGF group was significantly higher than the A value of the control group. Furthermore, the A value of the Cur group was significantly lower compared to the rhbFGF group, with an inhibition of 53.7%. Five different protein spots were obtained from proliferative HLE-B3 cells induced by rhbFGF. Eight different protein spots were obtained in HLE-B3 cells incubated with Cur. There were the common variational protein spots at mass/charge (m/z) ratios of 8 093 and 13 767 between rhbFGF group and control group as well as between the Cur group and rhbFGF group. Conclusions: These results show that Cur effectively inhibited HLE-B3 cell proliferation induced by rhbFGF. The protein spots at m/z of 8 093 and 13 767 may be the targets of Cur-induced inhibition of HLE-B3 cell proliferation. Cur may be a reliable and effective drug for prevention and treatment of polymerase chain reaction (PCR)