Existence Theory for the Radically Symmetric Contact Lens Equation

In this paper we present a variational formulation of the problem of determining the elastic stresses in a contact lens on an eye and the induced suction pressure distribution in the tear film between the eye and the lens. This complements the force-balance derivation that we used in earlier work [K. L. Maki and D. S. Ross, J. Bio. Sys., 22 (2014), pp. 235–248]. We investigate the existence of solutions of the relevant boundary value problem for the singular, second-order Euler–Lagrange equation. We prove that, for lenses of constant thickness, solutions exist. We present an example to show that in some cases in which the lens thickness increases with distance from the lens center no solution exists

Medical Student Competency in Wound Care Guidelines

Chronic wounds that have failed to heal after 3 months of appropriate wound care affect approximately 6.5 million people in the US with a prevalence of 1% and costs estimated at $25 billion per year. Medical students currently receive limited wound care training, yet to effectively manage chronic wounds, providers must both understand the biology of healing, and also remain up-to-date with wound care guidelines published by the Agency for Healthcare Research and Quality (AHRQ). The purpose of this student-led project was to investigate medical students\u27 knowledge and comfort with wound care guidelines

Mimicry and mitonuclear discordance in nudibranchs : new insights from exon capture phylogenomics

Open access via the Wiley Jisc Agreement Funding Information Gorgon Barrow Island Net Conservation Benefits Fund The University of Western Australia Malacological Society of Australasia ACKNOWLEDGEMENTS We are grateful to our collaborators who have contributed specimens to this work, including David Mullins, Gary Cobb, Greg Rouse, Karen Cheney, Kate Dawson, Lisa Kirkendale, Terry Farr, and Terry Gosliner. We also thank Elizabeth Kools for coordinating K.K.S.L's tissue sampling at the California Academy of Sciences and for sending specimens for this work. We sincerely thank Alison Devault and Jakob Enk from Arbor Biosciences for logistical support and advice, and Greg Rouse, Joel Huey, and Josefin Stiller for feedback on data analysis. Funding for this project comes from the Gorgon Project's Barrow Island Net Conservation Benefits Fund, The University of Western Australia, and the Malacological Society of Australasia. K.K.S.L. was supported by a University Postgraduate Award for International Students (UPAIS) and an RTP International Fees Offset scholarship (RTPFI) administered by the University of Western Australia, as well as a postgraduate doctoral scholarship from the Natural Sciences and Engineering Research Council of Canada (NSERC). Here we provide permit details for newly collected specimens that do not derive from Layton et al. (2018). Specimens from Western Australia were collected under permits from the Department of Parks and Wildlife, including a regulation 17 licence to collect fauna for scientific purposes (SF010218, SF010710) and a regulation 4 exemption to collect marine invertebrates within Ningaloo Marine Park (CE005306). Specimens from Queensland were collected under permits from the Department of Agriculture, Fisheries and Forestry (Permit #: 183990). Specimens from Victoria were collected under permits from the Department of Environment, Land, Water and Planning (Permit #: 10007853). The specimen from California was collected under a permit from California Department of Fish and Wildlife (Permit #: 4564).Peer reviewedPublisher PD

A newly discovered radiation of endoparasitic gastropods and their coevolution with asteroid hosts in Antarctica

Funding Funding for this research comes from the Antarctic Circumnavigation Expedition, The University of Western Australia, and the National Science Foundation (USA) ANT-1043749. KKSL was supported by a University Postgraduate Award for International Students (UPAIS) and an RTP International Fees Offset scholarship (RTPFI) administered by The University of Western Australia, as well as a postgraduate doctoral scholarship from the Natural Sciences and Engineering Research Council of Canada (NSERC). These funding bodies did not have a role in the design of the study, the collection, analysis, and interpretation of data, or in writing the manuscript. Availability of data and materials The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request and GenBank accessions appear in the manuscript.Peer reviewedPublisher PD

Exploring Canadian Echinoderm Diversity through DNA Barcodes

Funding: This research was funded, in part, by the Natural Sciences and Engineering Research Council (NSERC) through a Discovery Grant to PDNH and a postgraduate scholarship to EAC. Sequence analysis was enabled by funding from the government of Canada through Genome Canada and the Ontario Genomics Institute in support of the International Barcode of Life Project (OGI-036). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgments We thank Bridgette Clarkston, Christina Carr, Claudia Hand, Jeremy deWaard, Jim Boutillier, Katy Hind, Robert Frank, Sandra McCubbin, Tanya Brown, Tom Sheldon, and Victoria Frank for contributing specimens and aiding in collections. Kelly Sendall kindly provided access to the echinoderm collections at the Royal British Columbia Museum while we deeply appreciate the help that Chris Mah, Melissa Frey, and Phil Lambert provided with identifications. We also thank staff at the Canadian Centre for DNA Barcoding in the CBG for their aid in sequence acquisition. Lastly, we thank O.S. Klanten and two anonymous reviewers for their helpful suggestions on earlier versions of this manuscript.Peer reviewedPublisher PD

Maternal and fetal outcomes of COVID-19, SARS, and MERS: a narrative review on the current knowledge

OBJECTIVE: Coronavirus infections, including SARS. MERS and COVID-19 have significant impact on global health as well as on pregnancies. The aim of this review was to enlighten and summarize the cumulative knowledge regarding the relationship between Coronavirus outbreaks and pregnancy. MATERIALS AND METHODS: Literature search was commenced in order to analyze the maternofetal effects of Coronavirus outbreaks. RESULTS: Fever and cough are the most common presenting symptoms of COVID-19 which mostly affects pregnant women in their 3rd trimester with a maternal mortality rate of 0-77% and fetal and neonatal mortality rates of 1.2%. Fetal demise is common in critically ill pregnant. Pregnancy seems as a worsening factor for SARS and MERS epidemics and both infections affect prominently 3rd trimester pregnancies, although abortion (57%) is a significant risk for cases of early pregnancy. Clinical course of COVID-19, SARS and MERS may be rapid and worse in pregnant women than non-pregnant individuals. Cesarean section is the choice of delivery in most reported women due to mostly obstetrical reasons, although vaginal delivery seems not a worsening factor for the disease.CONCLUSIONS: COVID-19, SARS and MERS have significant detrimental effect on pregnancy. Rapid intervention, treatment, and intensive care support are essential for infected pregnant. Timely delivery is important in order to avoid intrauterine fetal death

The effect of anatomic differences on the relationship between renal artery and diaphragmatic crus

Background: The aim of this study is to investigate the effect of anatomic differences on the relationship between renal artery and diaphragmatic crus via the touch of two structures. Materials and methods: The study included dynamic computed tomography (CT) scans of 308 patients performed mainly for characterisation of liver and renal masses. Anatomic differences including the thickness of the diaphragmatic crus, the localisation of renal artery ostium at the wall of aorta, the level of renal artery origin with respect to superior mesenteric artery were evaluated. Statistical relationships between renal artery-diaphragmatic crus contact and the anatomic differences were assessed. Results: Thickness of the diaphragmatic crus at the level of renal artery origin exhibited a statistically significant relationship to renal artery-diaphragmatic crus contact at the left (p < 0.001) and right side (p < 0.001). There was a statistically significant relationship between high renal artery origin and renal artery- -diaphragmatic crus contact at the left (p < 0.001) and right side (p = 0.01). The localisation of renal artery ostium at the wall of aorta (right side, p = 0.436, left side, p = 0.681) did not demonstrate a relationship to renal artery-diaphragmatic crus contact. Conclusions: Thickness of the diaphragmatic crus and high renal artery origin with respect to superior mesenteric artery are crucial anatomic differences determining the relationship of renal artery and diaphragmatic crus. (Folia Morphol 2018; 77, 1: 22–28)

Implementing Pharmacy Informatics in College Curricula: The AACP Technology in Pharmacy Education and Learning Special Interest Group

Many professional organizations have initiatives to increase the awareness and use of informatics in the practice of pharmacy. Within education we must respond to these initiatives and make technology integral to all aspects of the curriculum, inculcating in students the importance of technology in practice. This document proposes 5 central domains for organizing planning related to informatics and technology within pharmacy education. The document is intended to encourage discussion of informatics within pharmacy education and the implications of informatics in future pharmacy practice, and to guide colleges of pharmacy in identifying and analyzing informatics topics to be taught and methods of instruction to be used within the doctor of pharmacy curriculum