Validacija hrvatske verzije upitnika o strahu od operacije u odraslih bolesnika planiranih za elektivni zahvat

The Surgical Fear Questionnaire (SFQ) is an instrument for self-assessment of surgical fear and consists of two subscales, one assessing the fear of short-term consequences (SFQ-s) and another one of long-term consequences (SFQ-l) of surgery. The aim of this study was to test the Croatian version of the SFQ with regard to its psychometric properties. This prospective cohort study included patients who presented to the Department of Surgery for elective surgery in the inpatient setting at a tertiary health care facility in Croatia between April 1 and May 31, 2019. Data on 144 patients were suitable for data analysis. Data collection was performed in the afternoon before surgery using the Personal Information Form, Numerical Rating Scale self-report instruments (NRS), SFQ and Hospital Anxiety and Depression Scale (HADS) assessing sociodemographic factors, surgical fear via NRS and SFQ, expected pain and emotional state. The Cronbach alpha value as a statistical measure for reliability of psychometric tests for the SFQ-s subscale was 0.79, for SFQ-L subscale 0.84, and for total SFQ 0.81. The exploratory factor analysis (EFA) showed a two-factor structure. Significant correlations of the SFQ with the NRS and HADS-anxiety subscale were demonstrated. Our study demonstrated the Croatian version of the SFQ to have a high level of reliability and hence can be used as a self-report instrument for surgical fear with two subscales. Convergent validity of the SFQ with other self-report instruments is shown.Surgical Fear Questionnaire (SFQ) je instrument za procjenu straha od operacije, a sastoji se od dvije podljestvice: jedna ispituje strah od kratkoročnih posljedica (SFQ-s), a druga strah od dugoročnih posljedica (SFQ-l) operativnog zahvata. Cilj ove studije bio je testirati psihometrijska svojstva hrvatske inačice SFQ. Ova prospektivna kohortna studija uključivala je bolesnike hospitalizirane na Klinici za kirurgiju zbog planiranog elektivnog operativnog zahvata u sklopu jedne zdravstvene ustanove treće razine u Hrvatskoj od 1. travnja do 31. svibnja 2019. godine; podatci 144 ispitanika pokazali su se pogodnima za analizu. Prikupljanje podataka odvijalo se tijekom poslijepodneva na dan prije operacije uz primjenu Obrasca za osobne podatke, Brojčane ljestvice (NRS), SFQ te Hospital Anxiety and Depression scale (HADS) kojima su se dobile informacije o sociodemografskim čimbenicima, strahu od operacije preko NRS i SFQ, očekivanoj boli te o emotivnom stanju. Mjerena je vrijednost Cronbach alfa kao statistička mjera za pouzdanost psihometrijskih testova; ona je za SFQ-s iznosila 0,79, za SFQ-l 0,84, a za ukupni SFQ 0,81. Eksploratorna faktorska analiza (EFA) pokazala je dvofaktornu strukturu upitnika. Dokazane su značajne korelacije SFQ-a s ljestvicama NRS i HADS-anksioznost. Naša studija pokazala je kako hrvatska inačica SFQ ima visoku razinu pouzdanosti te se stoga može rabiti kao instrument za procjenu straha od operacije s dvije podljestvice. Dokazana je konvergentna valjanost SFQ s drugim instrumentima

Lipid peroxidation in obesity: Can bariatric surgery help?

Obesity and chronic oxidative stress, often being associated with each other in a vicious circle, are important factors of chronic diseases. Although it was usually considered to accompany aging and wealth, global trends show the increase in obesity among children even in Third World countries. Being manifested by an imbalance between energy consumption and food intake, obesity is characterized by an excessive or abnormal fat accumulation, impaired redox homeostasis and metabolic changes often associated with the self- catalyzed lipid peroxidation generating 4- hydroxynonenal, pluripotent bioactive peroxidation product of polyunsaturated fatty acids. Conservative methods targeting obesity produced only modest and transient results in the treatment of morbid obesity. Therefore, in recent years, surgery, primarily bariatric, became an attractive treatment for morbid obesity. Since adipose tissue is well known as a stress organ with pronounced endocrine functions, surgery results in redox balance and metabolic improvement of the entire organism. The source of bioactive lipids and lipid- soluble antioxidants, and the complex pathophysiology of lipid peroxidation should thus be considered from the aspects of personalized and integrative biomedicine to treat obesity in an appropriate way

Validation of the Croatian Version of the Surgical Fear Questionnaire (Sfq) in Adult Patients Waiting for Elective Surgery

The Surgical Fear Questionnaire (SFQ) is an instrument for self-assessment of surgical fear and consists of two subscales, one assessing the fear of short-term consequences (SFQ-s) and another one of long-term consequences (SFQ-l) of surgery. The aim of this study was to test the Croatian version of the SFQ with regard to its psychometric properties. This prospective cohort study included patients who presented to the Department of Surgery for elective surgery in the inpatient setting at a tertiary health care facility in Croatia between April 1 and May 31, 2019. Data on 144 patients were suitable for data analysis. Data collection was performed in the afternoon before surgery using the Personal Information Form, Numerical Rating Scale self-report instruments (NRS), SFQ and Hospital Anxiety and Depression Scale (HADS) assessing sociodemographic factors, surgical fear via NRS and SFQ, expected pain and emotional state. The Cronbach alpha value as a statistical measure for reliability of psychometric tests for the SFQ-s subscale was 0.79, for SFQ-L subscale 0.84, and for total SFQ 0.81. The exploratory factor analysis (EFA) showed a two-factor structure. Significant correlations of the SFQ with the NRS and HADS-anxiety subscale were demonstrated. Our study demonstrated the Croatian version of the SFQ to have a high level of reliability and hence can be used as a self-report instrument for surgical fear with two subscales. Convergent validity of the SFQ with other self-report instruments is shown