Standardization of Terminology in Laboratory Medicine II

Standardization of medical terminology is essential in data transmission between health care institutes and in maximizing the benefits of information technology. The purpose of this study was to standardize medical terms for laboratory observations. During the second year of the study, a standard database of concept names for laboratory terms that covered those used in tertiary health care institutes and reference laboratories was developed. The laboratory terms in the Logical Observation Identifier Names and Codes (LOINC) database were adopted and matched with the electronic data interchange (EDI) codes in Korea. A public hearing and a workshop for clinical pathologists were held to collect the opinions of experts. The Korean standard laboratory terminology database containing six axial concept names, components, property, time aspect, system (specimen), scale type, and method type, was established for 29,340 test observations. Short names and mapping tables for EDI codes and UMLS were added. Synonym tables were prepared to help match concept names to common terms used in the fields. We herein described the Korean standard laboratory terminology database for test names, result description terms, and result units encompassing most of the laboratory tests in Korea

인체 폐종양 세포주에서 MHC 항원 표현 정도와 자연살세포(NK)의 세포 살해 효과와의 상관관계에 관한 연구

Lung carcinoma cell lines (NCI-N417, NCI-NI46, NCI-H69, PC-14) were evaluated on their expression of HLA-class I with W6/32 antibody and HLA-class II with L243 by flow cytometry. Also examined were the killing and/or cytolytic effects of allogeneic NK cells and T lymphocytes as effector cells to the lung carcinoma cell lines by chromium release assay, before and after treatments with gamma interferon. HLA class I expressions significantly increased after treatment with gamma interferon (P 0.05). The killing and/or cytolytic effects of allogeneic NK cells very significantly decreased after treatment with gamma interferon (P <0.001), while those of the T lymphocytes showed either no change or a tendancy to decrease (P > 0.05)