A Comprehensive Review on the Therapeutic Applications and Synthetic Approaches of Buparvaquone

Buparvaquone 1a is a predominant anti-protozoal drug, it belongs to the pharmacologically active class of hydroxy-naphthoquinones. There are numerous publications on the wide therapeutic applications of 1a, but only a few approaches were reported towards its synthesis. Most of the prior arts report the synthesis from expensive raw materials with low yield, whereas only a few involves the use of readily available and less expensive raw materials with moderate to better yield. The present review work covers the developments on therapeutic applications of 1a along with the synthetic approaches disclosed till date