Forty-Four Pass Fibre Optic Loop for Improving the Sensitivity of Surface Plasmon Resonance Sensors

A forty-four pass fibre optic surface plasmon resonance sensor that enhances detection sensitivity according to the number of passes is demonstrated for the first time. The technique employs a fibre optic recirculation loop that passes the detection spot forty- four times, thus enhancing sensitivity by a factor of forty-four. Presently, the total number of passes is limited by the onset of lasing action of the recirculation loop. This technique offers a significant sensitivity improvement for various types of plasmon resonance sensors that may be used in chemical and biomolecule detections.Comment: Submitted for publication; patent disclosure submitte

Exclusive Measurement of the Nonmesonic Weak Decay of ^{5}_{\Lambda}He Hypernucleus

We performed a coincidence measurement of two nucleons emitted from the nonmesonic weak decay (NMWD) of ^{5}_{\Lambda}He formed via the ^{6}Li(\pi^+,K^+) reaction. The energies of two nucleons and the pair number distributions in the opening angle between them were measured. In both np and nn pairs, we observed a clean back-to-back correlation coming from the two-body decay of \Lambda p --> n p and \Lambda n --> n n, respectively. The ratio of the nucleon pair numbers was N_{nn}/N_{np}=0.45 \pm 0.11(stat)\pm 0.03(syst) in the kinematic region of cos(theta_{NN}) < -0.8. Since each decay mode was exclusively detected, the measured ratio should be close to the ratio of \Gamma(\Lambda p --> np)/\Gamma(\Lambda n --> nn). The ratio is consistent with recent theoretical calculations based on the heavy meson/direct quark exchange picture.Comment: Submitted to Phys. Rev. lett., 4 pages, 3 figure

Sero- and Molecular Epidemiology of HIV-1 in Papua Province, Indonesia

Background: human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) cause serious health problems and affect the Indonesian economy. Papua province has the highest prevalence of HIV infection in the country; however, epidemiological data are limited. Therefore, in order to reveal the current situation of HIV/AIDS in Papua province, sero- and molecular epidemiological studies of HIV were conducted. Methods: serological tests were conducted on 157 healthy individuals from the general population residing in Paniai, Papua. In addition, a molecular epidemiological study was then conducted on HIV type 1 (HIV-1) genes derived from infected individuals. Peripheral blood samples from HIV-1-positive individuals and 15 additionally enrolled, previously confirmed HIV-1-positive individuals were subjected to a genotypic analysis. Results: serological tests revealed that 2 out of 157 (1.27%) healthy individuals were HIV-positive. In addition, HIV-1 subtyping revealed that subtype B and CRF01_AE were the major subtype and circulating recombinant form (CRF) of HIV-1 prevalent in the region, while subtype A1 and a recombinant form including viral gene fragments of CRF01_AE and subtype B was also detected. In addition, HIV drug resistance-associated major mutations were detected in the reverse transcriptase gene derived from infected individual on antiretroviral therapy. Conclusion: these results provide important information for clearer understanding on the current situation of HIV/AIDS in Papua province in Indonesia

Measurement of the π−\pi^- decay width of Λ5^5_\LambdaHe

We have precisely measured $\Lambda \to p\pi^-$ decay width of \5LHe and demonstrated significantly larger $\alpha$ -$\Lambda$ overlap than expected from the central repulsion $\alpha$-$\Lambda$ potential, which is derived from YNG \Lambda$-nucleon interaction.Comment: 4 pages, 3 figure

Proton asymmetry in non-mesonic weak decay of light hypernuclei

We have obtained the decay asymmetry parameters in non-mesonic weak decay of polarized Lambda-hypernuclei by measuring the proton asymmetry. The polarized Lambda-hypernuclei, 5_Lambda-He, 12_Lambda-C, and 11_Lambda-B, were produced in high statistics via the (pi^+,k^+) reaction at 1.05 GeV/c in the forward angles. Preliminary analysis shows that the decay asymmetry parameters are very small for these s-shell and p-shell hypernuclei.Comment: 4pages, 4figures, International Conference on Hypernuclear and Strange Particle Physics (HYP2003

pi^0 decay branching ratios of 5_Lambda-He and 12_Lambda-C hypernuclei

We precisely measured pi^0 branching ratios of 5_Lambda-He and 12_Lambda-C hypernuclei produced via (pi^+,k^+) reaction. Using these pi^0 branching ratios with the pi^- branching ratios and the lifetimes, we obtained the pi^0 decay widths and the non-mesonic weak decay widths at high statistics with the accuracy of ~5 % (stat) for both hypernuclei.Comment: 4pages, 4figures, International Conference on Hypernuclear and Strange Particle Physics (HYP2003

Nucleon-nucleon coincidence measurement in the non-mesonic weak decay of 5_Lambda-He and 12_Lambda-C hypernuclei

We have measured both yields of neutron-proton and neutron-neutron pairs emitted from the non-mesonic weak decay process of 5_Lambda-He and 12_Lambda-C hypernuclei produced via the (pi^+,K^+) reaction for the first time. We observed clean back-to-back correlation of the np- and nn-pairs in the coincidence spectra for both hypernuclei. The ratio of those back-to-back pair yields, Nnn / Nnp, must be close to the ratio of neutron- and proton-induced decay widths of the decay, Gn(Lambda n -> nn)/Gp(Lambda p -> np). The obtained ratios for each hypernuclei support recent calculations based on short-range interactions.Comment: 4 pages, 1 figure, International Nuclear Physics Conference (INPC 2004), Goteborg, Sweden, June 27 - July 2, 2004, to appear in Nuclear Physics

Matrin 3 and HIV Rev Regulation of mRNA

The nuclear matrix protein, MATR3, is a newly-described Rev cofactor whose mechanism of action is only starting to be revealed

Measurements of total and partial charge-changing cross sections for 200-400 MeV/nucleon 12C in water and polycarbonate

We have studied charged nuclear fragments produced by 200 - 400 MeV/nucleon carbon ions, interacting with water and polycarbonate, using a newly developed emulsion detector. Total and partial charge-changing cross sections for the production of B, Be, and Li fragments were measured and compared with both previously published measurements, and model predictions. This study is of importance for validating and improving carbon ion therapy treatment planning systems, and for estimating the radiological risks for personnel on space missions, since carbon is a significant component of the Galactic Cosmic Rays