On the effect of chelating agents and antioxidants on cadmium-induced organ toxicity. An overview

Cadmium (Cd) has been classified as a human carcinogen. The World Health Organization (WHO) reported that the concentration of Cd in the environment has rapidly increased in the last few years. In many epidemiological studies, the correlation between environmental exposure of humans to Cd and diseases such as stroke, ischemia, renal and hepatic dysfunction, anemia, osteoporosis and diabetes has been discussed. For the treatment of heavy metal intoxications a therapy with chelating agents has been applied. A chelating agent is a compound that binds the toxic metal ion thus promoting its excretion by the living organisms. Recently, it has been found that Cd-induced toxicity is a result of formation of reactive oxygen species (ROS). These results increased the interest towards the antioxidants as possible agents for the treatment of Cd-induced organ toxicity. Herein, we present summary and discussion of the literature data for the influence of chelating agents and antioxidants on Cd-induced pathological conditions in Cd-intoxicated animals

The response strategy of social work with displaced families and the receiving community (within the context of sustainable development)

The article deals with the issues of overcoming poverty, inequality, nutrition improvement, ensuring a healthy way of life, raising education quality, enhancing well-being, and building up a peaceful and open society for internally displaced persons (IDP) and the receiving community by means of the social response strategy. The goal of the research: theoretic substantiation of the response strategy in social work with IDP and the community in the context of the perspective of ensuring their sustainable development. The presented response strategy is for the first time theoretically substantiated and adapted to the Ukrainian realities in the conflict zone and takes into account the peculiarities of the DP and social work in the receiving borderline community and includes standard actions to react to extraordinary situations, activity directions – psychology-and-pedagogic, socio-medical, humanitarian, information-and-cultural assistance. The strategy is based on the principles of integration, multi-sidedness, multidisciplinary connection, resource-orientation, green-aware social work, the advantages theory, partnership, assistance for self-assistance, family-centrism, innovation, synergy, etc.; it takes into account the perspective ensuring of sustainable future for both the displaced families and the receiving community in general. The methods of the research: theoretical analysis, synthesis, systemizing, generalizing, comparison, documentation study, estimation of needs, and mathematic statistics methods. The obtained results of applying the mentioned theory under conditions of the military conflict in the Luhansk oblast (area) of Ukraine confirm its efficiency in qualitative and numerical terms and are supported by mathematic statistics methods

A research on transformation of social wellbeing and life attitudes in students from the occupied territories and the demarcation line at relocated higher education institutions from the east of Ukraine

We connect the urgency of the article with the preservation of the integrity of Ukraine in the conditions of military conflict. The article describes the research on transformation of the current state of social wellbeing and life attitudes in students from the occupied territories of Ukraine under conditions of relocated higher education institutions. The goal: to study the transformation in social wellbeing and life attitudes in the mentioned strata of students under conditions of operation of a relocated state higher education institution. The methods: analysis, synthesis, generalization, specification, systematizing, comparison, documentation study, interviewing, mathematics statistics methods. Scientific novelty: theoretical foundations and the essence of reintegration of such students, as well as the measures are determined that facilitate it: information and explanatory work, socio-educational, psychological, pedagogical, socio-economic, and legal ones. It is proved that national-oriented upbringing is the priority in successful reintegration on condition of solving students' problems. The results: the efficiency in the use of the mentioned measures is proved by transformational changes related to overcoming the imbalance between the social wellbeing indicators (the level of life satisfaction, interest in life, general mood) and life attitudes (focus on process, result, freedom) of such students