Analytical and Synthetic Studies of Boronic Acids and Their Derivatives

The discovery in 1954 of the selective reactions of boronic acids with proximal diols, and subsequent studies of other bi-functional substrates, affording cyclic derivatives, opened a new field in studying the chemical properties of these polyfunctional compounds. A wide range of specific boronates has been prepared, and many workers have shown how useful they can be for example, as crystalline derivatives, reagents for structural analysis, intermediates in synthesis, derivatives for use in a range of separatory techniques, and reaction catalysts. Boronic acids and their derivatives are also of potential value in cancer therapy and possibly as hormone analogues

(20S)-22-Acetoxymethyl-6β-meth­oxy-3α,5-dihydro-3′H-cyclo­propa[3α,5]-5α-pregnane

In the title steroid derivative, C25H40O3, the fused cyclo­propane unit that corresponds to a part of the A ring has a β-configuration and the associated cyclo­pentane ring an envelope-shaped conformation

(20R,24R,25S)-3α,7α,12α,27-Tetra­acet­oxy-24,26-ep­oxy-5β-cholestane

In the title anhydro­scymnol tetra­acetate, C35H54O9, the fused chair conformation of the cyclo­hexane A/B ring junction is cis with a 5β-H configuration. The compound has a trimethyl­ene oxide ring at position 24,26 and four acetate groups at the 3α,7α,12α,27 positions

Spectroscopic properties and optoelectronic parameters of ternary composites incorporating poly(L-Tryptophane):P(TER-CO-TRI) and Sudan dye

In this study, the spectroscopic properties and optoelectronic parameters of a ternary composite containing poly(L-Tryptophane): P(TER-CO-TRI) and Sudan dye were thoroughly investigated. Poly(L-Tryptophane) and P (TER-CO-TRI), the electron acceptor and donor, were solution processed and doped with different ratios of Sudan dye to form ternary composite systems. The FTIR technique, UV-Vis spectroscopy, and cyclic voltammetry (CV) were utilized to study the broad properties of the samples. Results showed that with the help of dye doping, the non-dispersive refractive index and energy gap of the ternary system were increased to 2.00 and decreased to 2.11 eV, respectively. The optical band gap, refractive index, dielectric constant, and optical conductivity of the samples were elaborated. The nature of the electronic transition in the studied samples was found to be a direct allowed transition, which was derived from the application of Tauc’s equation. The combination of CV test and absorption spectroscopy was successfully used to determine the molecular energy levels, HOMO and LUMO of the polymer samples

(20S)-22-Iodo­methyl-6β-meth­oxy-3α,5-dihydro-3′H-cyclo­propa[3α,5]-5α-pregnane

In the title steroid derivative, C23H37IO, the fused cyclo­propane unit that comprises part of the A ring has a β-configuration, and the associated cyclo­pentane ring has an envelope conformation

(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis­(propano­yloxy)-5β,8β-epoxy­pregna-1,9-diene

The title compound, C28H34Cl2O7, is a derivative of the glucocorticoid steroid beclomethasone dipropionate. It features an expoxide linkage [angle at oxygen = 96.6 (2)°]. The dichlorocyclohexenone ring adopts an envelope conformation, with the C atom bearing the two Cl substituents representing the flap. The dichloro­methyl C atom deviates by 0.471 (4) Å from the plane defined by the other five atoms, whose maximum r.m.s. deviation is 0.04 Å

The role of gender mainstreaming in city-level interventions and leadership: examples from Manila, Duhok and Sanandaj. SUEUAA Thematic Paper Series, TPS 103/18

Making space for women in universities and encouraging their participation in various sectors have become some of the primary goals on many national and regional agendas in the Global South. However, feminist scholars have pointed out that gender mainstreaming failed to accomplish its goals as it primarily encouraged the integration of women in already compromised neoliberal and patriarchal structures, therefore ignoring the collective responsibilities for gender-based inequalities (Alston, 2014). Recently, there has been a shift by feminist researchers to focus on wider issues of gender and development, to account for the wide range of interrelated issues which may be at play in gender-based inequalities. In this paper, we explore the policies and actions towards gender mainstreaming (both in terms of public engagement, interventions, as well as discussions surrounding empowerment of women). By looking at three case study cities, Manila (Philippines), Duhok (Iraq) and Sanandaj (Iran), we argue that focusing on gender mainstreaming demonstrates both the ways in which women navigate infrastructures in order to make an impact on their communities, but also the areas of development that need to further tackle gender-based inequalities

17-Deoxoestrone [estra-1,3,5(10)-trien-3-ol]–methanol (3/1)

Three independent mol­ecules of the title estrone derivative and a mol­ecule of methanol comprise the asymmetric unit of the title compound [systematic name: 13-methyl-6,7,8,9,11,12,13,14,15,16-deca­hydro­cyclo­penta­[a]phenanthren-3-ol–meth­an­ol (3/1)], 3C18H24O·CH3OH. Two of the estrone mol­ecules exhibit 50:50 disorder (one displays whole-mol­ecule disorder and the other partial disorder in the fused five- and six-membered rings) so that five (partial) mol­ecular conformations are discernable. The conformation of the six-membered ring abutting the aromatic ring is close to a half-chair in all five components. The conformation of the six-membered ring fused to the five-membered ring is based on a chair with varying degrees of distortion ranging from minor to significant. Two distinct conformations are found for the five-membered ring: in four mol­ecules, the five-membered ring is twisted about the bond linking it to the six-membered ring, and in the other, the five-membered ring is an envelope with the quaternary C atom being the flap atom. The crystal packing features O—H⋯O hydrogen bonding whereby the four mol­ecules comprising the asymmetric unit are linked into a supra­molecular chain along the b axis

3-Methyl-5α-cholest-2-ene

In the title cholestane derivative, C28H48 [systematic name: (1S,2S,7R,10R,11R,14R,15R)-2,5,10,15-tetra­methyl-14-[(2R)-6-methyl­heptan-2-yl]tetra­cyclo­[8.7.0.02,7.011,15]hepta­dec-4-ene], the cyclo­hexene ring adopts a half-chair conformation. The parent 5α-cholest-2-ene and the equivalent fragment of the title compound are almost superimposable (r.m.s. deviation = 0.033 Å)

(20R,24R,25S)-3α,7α,12α,27-Tetraacetoxy-24,26-epoxy-5β-cholestane

In the title anhydro­scymnol tetra­acetate, C35H54O9, the fused chair conformation of the cyclo­hexane A/B ring junction is cis with a 5β-H configuration. The compound has a trimethyl­ene oxide ring at position 24,26 and four acetate groups at the 3α,7α,12α,27 positions