INCREASE IN THE EFFICIENCY OF FUNCTIONING OF PROCESSING LINES BASED ON THE SYSTEM ANALYSIS OF STABILITY OF SPECIFIC OPERATIONS

To develop processing lines, it is necessary to calculate the level of integrity of technological systems and determine the stability of subsystems at a certain level of stability. The complex analysis allows us to study a change in the entropy of the system (the growth of system stability) by describing the mechanism of structural information accumulation. Identifying the ranges of variation of adjustable operating parameters using the proposed approach for energy and resource saving and predicting the stability of the line at the design stage, reducing the subjectivity of estimation of technologies and their hardware design, is original and, in this regard, relevant. The studies were conducted to justify the estimation of the stability of the technological flow as a system and its subsystems in their interconnection at a certain level of stability using the method for estimating fuzzy entropy on the basis of analysis of material and technical flows. The study objects are the integrity of technological and technical systems, the stability of processes, operations and equipment operation. As a result of the analysis of technological flows and a change in the entropy of the technical system, the mechanism of accumulation of structural information entropy has been studied. The carried out analytical and experimental studies have confirmed the possibility of predicting the stability of the operation of technical and technological systems, as well as the expediency of determining the ranges of variation in the parameters of operation of the lines, technological limits and the quality indicators of the finished and semi-finished products. Thus, this method is recommended for use in the food industry

Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: One-Year Follow-up.

Declines in stroke admission, intravenous thrombolysis, and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the impact of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), intravenous thrombolysis (IVT), and mechanical thrombectomy over a one-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, intravenous thrombolysis treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. There were 148,895 stroke admissions in the one-year immediately before compared to 138,453 admissions during the one-year pandemic, representing a 7% decline (95% confidence interval [95% CI 7.1, 6.9]; p<0.0001). ICH volumes declined from 29,585 to 28,156 (4.8%, [5.1, 4.6]; p<0.0001) and IVT volume from 24,584 to 23,077 (6.1%, [6.4, 5.8]; p<0.0001). Larger declines were observed at high volume compared to low volume centers (all p<0.0001). There was no significant change in mechanical thrombectomy volumes (0.7%, [0.6,0.9]; p=0.49). Stroke was diagnosed in 1.3% [1.31,1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82,2.97], 5,656/195,539) of all stroke hospitalizations. There was a global decline and shift to lower volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared to the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year. This study is registered under NCT04934020