Implementasi Program Pemberdayaan Ekonomi Rakyat Melalui Program Mamangun Tuntang Mahaga Lewu (Pm2l) (Studi Kasus Di Dua Desa Tertinggal Di Kalimantan Tengah)

This study aims to determine the implementation of the program of economic empowerment of the people through the program mamangun Tuntang mahaga Lewu (PM2L). Writing method used is qualitative. This method was chosen because it examines the phenomenon of something in more depth, and more able to understand the phenomenon that until now has not been known. Through this study were obtained in the implementation of key information that PM2L are several stages to go through the stage of coordination, socialization, implementation of the action, coaching, monitoring and evaluation. In general, the stages through which it has not been optimal program implementation in practice, especially in terms of stages of development

Additional file 2: of Enhancing circadian clock function in cancer cells inhibits tumor growth

Supplementary methods. (PDF 184 kb

Additional file 9: of Enhancing circadian clock function in cancer cells inhibits tumor growth

Immune cell infiltration, apoptosis and cell cycle arrest in NSG mice. Representative flow cytometry dot plots and quantification for neutrophils (F4/80 lowLy-6Ghigh, gated on CD11b+) (A), monocytes (CD11bhighLy-6Chigh, gated on F4/80+) (B), macrophages (F4/80highLy-6C- gated on CD11b+) (C), histogram and quantification for apoptosis (Annexin V) stained (red) and unstained (grey) cells (D) and dot plots and quantification of proliferation (Ki67) (E) at the indicated CTs in s.c. tumors after repeated intra-tumoral PBS or DEX injection every 2 days for 8–11 days in B16 s.c. tumors of NSG mice collected at CT14 (n = 4 mice/group, Mann-Whitney rank sum test: p > 0.05). (PDF 812 kb

JTK-Cycle analysis of 24 h rhythmicity in peripheral clock gene expression and plasma hormones.

<p>JTK-Cycle analysis of 24 h rhythmicity in peripheral clock gene expression and plasma hormones.</p

JTK-Cycle analysis of 24 h rhythmicity in clock gene expression in brain regions of interest.

<p>JTK-Cycle analysis of 24 h rhythmicity in clock gene expression in brain regions of interest.</p

Normalized clock gene expression at 6 times of day from adrenal gland (A–E) and stomach (F–J) tissue collected from groups of rats fed for 2 h daily at ZT4 (red dashed curve) or ZT16 (blue solid curve), or for 1 h at both times (green dotted curve).

<p>Normalized clock gene expression at 6 times of day from adrenal gland (A–E) and stomach (F–J) tissue collected from groups of rats fed for 2 h daily at ZT4 (red dashed curve) or ZT16 (blue solid curve), or for 1 h at both times (green dotted curve).</p

Group mean (± SEM) plasma corticosterone (A) and acyl-ghrelin (B) at 6 times of day from rats fed 2 h daily at ZT4 (red dashed curve) or ZT16 (blue solid curve), or for 1 h at both times (green dotted curve).

<p>The daily 12 h light and dark periods are indicated by the heavy yellow and black bars, respectively.</p

Group mean (± SEM) optical densities representing <i>Bmal1</i> mRNA from rats fed 2 h daily at ZT4 (red dashed curve) or ZT16 (blue solid curve), or for 1 h at both times (green dotted curve).

<p>A. Olfactory bulb, B. nucleus accumbens core, C. dorsal striatum, ventrolateral quadrant, D. nucleus accumbens shell, E. cerebellum, F. Arcuate nucleus.</p

Group mean (± SEM) optical densities representing <i>Bmal1</i> and <i>Per1</i> mRNA from the SCN (A–B) and dorsomedial hypothalamus (DMH, compact and ventral regions, C–F) in rats fed 2 h daily at ZT4 (red dashed curve) or ZT16 (blue solid curve), or for 1 h at both times (green dotted curve).

<p>Group mean (± SEM) optical densities representing <i>Bmal1</i> and <i>Per1</i> mRNA from the SCN (A–B) and dorsomedial hypothalamus (DMH, compact and ventral regions, C–F) in rats fed 2 h daily at ZT4 (red dashed curve) or ZT16 (blue solid curve), or for 1 h at both times (green dotted curve).</p